Access the full text.
Sign up today, get DeepDyve free for 14 days.
H. Wanebo, M. Ghebremichael, B. Burtness, S. Spencer, J. Ridge, A. Forastiere (2007)
Phase II evaluation of cetuximab (C225) combined with induction paclitaxel and carboplatin followed by C225, paclitaxel, carboplatin, and radiation for stage III/IV operable squamous cancer of the head and neck (ECOG, E2303)Journal of Clinical Oncology, 25
B. Glisson, B. Murphy, G. Frenette, F. Khuri, A. Forastiere (2002)
Phase II Trial of docetaxel and cisplatin combination chemotherapy in patients with squamous cell carcinoma of the head and neck.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 20 6
J. Beitler, J. Cooper (2009)
Seduction by induction?Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27 1
B. Burtness, M. Goldwasser, W. Flood, B. Mattar, A. Forastiere (2005)
Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 34
E. Cohen, D. Davis, T. Karrison, T. Seiwert, Stuart Wong, S. Nattam, M. Kozloff, Joseph Clark, D. Yan, Wen Liu, C. Pierce, J. Dancey, K. Stenson, E. Blair, A. Dekker, E. Vokes (2009)
Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study.The Lancet. Oncology, 10 3
B. Jeremic, Y. Shibamoto, B. Miličić, N. Nikolić, A. Dagović, J. Aleksandrovic, Z. Vaskoviĉ, L. Tadić (2000)
Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 18 7
G. Fountzilas, G. Stathopoulos, C. Nicolaides, A. Kalogera-Fountzila, H. Kalofonos, A. Nikolaou, C. Bacoyiannis, E. Samantas, C. Papadimitriou, P. Kosmidis, J. Daniilidis, N. Pavlidis (1999)
Paclitaxel and gemcitabine in advanced non-nasopharyngeal head and neck cancer: a phase II study conducted by the Hellenic Cooperative Oncology Group.Annals of oncology : official journal of the European Society for Medical Oncology, 10 4
G. Wolf, S. Fisher, W. Hong, Robert Hillman, M. Spaulding, G. Laramore, James Endicott, K. Mcclatchey, W. Henderson (1991)
Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer.The New England journal of medicine, 324 24
D. Shank A.A. Forastiere (1998)
Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck: An Eastern Cooperative Oncology Group Trial (PA390)Cancer, 82
J. Vermorken, É. Remenár, C. Herpen, T. Gorlia, R. Mesía, M. Degardin, J. Stewart, S. Jelić, J. Betka, J. Preiss, D. Weyngaert, A. Awada, D. Cupissol, H. Kienzer, A. Rey, Isabelle Desaunois, J. Bernier, J. Lefebvre (2007)
Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer.The New England journal of medicine, 357 17
A. Chan, B. Ma, Y. Lo, S. Leung, W. Kwan, E. Hui, T. Mok, M. Kam, L. Chan, S. Chiu, K. Yu, K. Cheung, K. Lai, M. Lai, F. Mo, W. Yeo, A. King, P. Johnson, P. Teo, B. Zee (2004)
Phase II study of neoadjuvant carboplatin and paclitaxel followed by radiotherapy and concurrent cisplatin in patients with locoregionally advanced nasopharyngeal carcinoma: therapeutic monitoring with plasma Epstein-Barr virus DNA.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22 15
G. Calais, M. Alfonsi, E. Bardet, C. Sire, T. Germain, P. Bergerot, B. Rhein, J. Tortochaux, P. Oudinot, P. Bertrand (2000)
Cancers de l'oropharynx de stades III et IV : résultats d'une étude randomisée du Gortec comparant radiothérapie exclusive et radiothérapie avec chimiothérapie concomitanteBulletin Du Cancer, 87
Ridge JA Adelstein DJ (2008)
Washington, D
D. Adelstein, J. Ridge, M. Gillison, A. Chaturvedi, P. Gravitt, W. Westra, A. Psyrri, W. Kast, L. Koutsky, A. Giuliano, S. Krosnick, A. Trotti, D. Schuller, A. Forastiere, C. Ullmann, H. Lee (2009)
HEAD AND NECK SQUAMOUS CELL CANCER AND THE HUMAN PAPILLOMAVIRUS: SUMMARY OF A NATIONAL CANCER INSTITUTE STATE OF THE SCIENCE MEETING,
S. Staar, V. Rudat, H. Stuetzer, A. Dietz, P. Volling, M. Schroeder, M. Flentje, H. Eckel, R. Mueller (2001)
Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy--results of a multicentric randomized German trial in advanced head-and-neck cancer.International journal of radiation oncology, biology, physics, 50 5
N. Dubrawsky (1989)
Cancer statisticsCA: A Cancer Journal for Clinicians, 39
J. Bernier, Christian Domenge, M. Ozsahin, K. Matuszewska, J. Lefebvre, R. Greiner, J. Giralt, P. Maingon, F. Rolland, M. Bolla, F. Cognetti, J. Bourhis, A. Kirkpatrick, M. Glabbeke (2004)
Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer.The New England journal of medicine, 350 19
A. Paccagnella, A. Orlando, C. Marchiori, Zorat Pl, G. Cavaniglia, V. Sileni, A. Jirillo, L. Tomio, G. Fila, A. Fede, L. Endrizzi, M. Bari, E. Sampognaro, M. Balli, A. Gava, G. Pappagallo, M. Fiorention (1994)
Phase III trial of initial chemotherapy in stage III or IV head and neck cancers: a study by the Gruppo di Studio sui Tumori della Testa e del Collo.Journal of the National Cancer Institute, 86 4
G. Calais, M. Alfonsi, É. Bardet, C. Sire, T. Germain, P. Bergerot, B. Rhein, J. Tortochaux, P. Oudinot, P. Bertrand (2000)
[Stage III and IV cancers of the oropharynx: results of a randomized study of Gortec comparing radiotherapy alone with concomitant chemotherapy].Bulletin du cancer, 87 Spec No
A. Forastiere, A. Trotti, D. Pfister, J. Grandis (2006)
Head and neck cancer: recent advances and new standards of care.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 17
P. Zorat, A. Paccagnella, G. Cavaniglia, L. Loreggian, A. Gava, C. Mione, Fanny Boldrin, C. Marchiori, F. Lunghi, A. Fede, A. Bordin, M. Mosto, V. Sileni, A. Orlando, A. Jirillo, L. Tomio, G. Pappagallo, M. Ghi (2004)
Randomized phase III trial of neoadjuvant chemotherapy in head and neck cancer: 10-year follow-up.Journal of the National Cancer Institute, 96 22
M. Kies, A. Garden, C. Holsinger, V. Papadimitrakopoulou, A. El-Naggar, K. Gillaspy, J. Lewin, Charles Lu, S. Villalobos, B. Glisson (2006)
Induction chemotherapy (CT) with weekly paclitaxel, carboplatin, and cetuximab for squamous cell carcinoma of the head and neck (HN).Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 18_suppl
R. Hitt, D. Castellano, M. Hidalgo, R. García-Carbonero, M. Peña, A. Brandáriz, J. Millán, J. Vincent, H. Cortés-Funes (1998)
Phase II trial of cisplatin and gemcitabine in advanced squamous-cell carcinoma of the head and neck.Annals of oncology : official journal of the European Society for Medical Oncology, 9 12
M. Gillison, W. Koch, R. Capone, M. Spafford, W. Westra, Li Wu, Marianna Zahurak, R. Daniel, M. Viglione, D. Symer, K. Shah, D. Sidransky (2000)
Evidence for a causal association between human papillomavirus and a subset of head and neck cancers.Journal of the National Cancer Institute, 92 9
J. Bernier, J. Cooper, T. Pajak, M. Glabbeke, J. Bourhis, A. Forastiere, E. Ozsahin, J. Jacobs, J. Jassem, K. Ang, J. Lefebvre (2005)
Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)Head & Neck, 27
G. Noël, J. Mazeron (2002)
Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy-results of a multicentric randomized German trial in advanced head-and-neck cancerCancer Radiotherapie, 6
M. Huncharek, B. Kupelnick (2002)
Combined Chemoradiation Versus Radiation Therapy Alone in Locally Advanced Nasopharyngeal Carcinoma: Results of a Meta-analysis of 1,528 Patients From Six Randomized TrialsAmerican Journal of Clinical Oncology, 25
W. Hong, Steven Schaefer, B. Issell, Charles Cummings, D. Luedke, R. Bromer, S. Fofonoff, Joan D'Aoust, S. Shapshay, J. Welch, E. Levin, Miriam Vincent, Charles Vaughan, S. Strong (1983)
A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neckCancer, 52
M. Hambek M. Baghi (2006)
A phase II trial of docetaxel, cisplatin and 5-fluorouracil in patients with recurrent squamous cell carcinoma of the head and neck (SCCHN)Anticancer Res, 26
D. Shin, B. Glisson, F. Khuri, L. Ginsberg, V. Papadimitrakopoulou, J. Lee, K. Lawhorn, A. Gillenwater, K. Ang, G. Clayman, D. Callender, W. Hong, S. Lippman (1998)
Phase II trial of paclitaxel, ifosfamide, and cisplatin in patients with recurrent head and neck squamous cell carcinoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 16 4
K. Lindel, K. Beer, J. Laissue, R. Greiner, D. Aebersold (2001)
Human papillomavirus positive squamous cell carcinoma of the oropharynxCancer, 92
F. Kamangar, G. Dores, W. Anderson (2006)
Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 14
D. Adelstein, Yi Li, G. Adams, H. Wagner, J. Kish, J. Ensley, D. Schuller, A. Forastiere (2003)
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 21 1
M. Maor A.A. Forastiere (2006)
Long-term results of intergroup RTOG 91-11: A phase III trial to preserve the larynx-induction cisplatin/5-FU and radiation therapyJ Clin Oncol, 24
C. Fakhry, W. Westra, Sigui Li, A. Cmelak, J. Ridge, H. Pinto, A. Forastiere, M. Gillison (2008)
Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial.Journal of the National Cancer Institute, 100 4
Induction chemotherapy : promises and limitations
M. Posner, Diane Hershock, C. Blajman, E. Mickiewicz, E. Winquist, V. Gorbounova, S. Tjulandin, Dong Shin, K. Cullen, Thomas Ervin, Barbara Murphy, Luis Raez, Roger Cohen, M. Spaulding, R. Tishler, B. Roth, Rosana Viroglio, V. Venkatesan, I. Romanov, S. Agarwala, K. Harter, M. Dugan, A. Cmelak, Arnold Markoe, Paul Read, L. Steinbrenner, A. Colevas, C. Norris, R. Haddad (2007)
Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer.The New England journal of medicine, 357 17
J. Pignon, A. Maître, E. Maillard, J. Bourhis (2009)
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 92 1
F. Denis, P. Garaud, É. Bardet, M. Alfonsi, C. Sire, T. Germain, P. Bergerot, B. Rhein, J. Tortochaux, G. Calais (2004)
Final results of the 94-01 French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22 1
W.M. Koch M.L. Gillison (2000)
Evidence for a causal association between human papillomavirus and a subset of head and neck cancersJ Natl Cancer Inst, 92
J. Cooper, T. Pajak, A. Forastiere, J. Jacobs, B. Campbell, S. Saxman, J. Kish, Harold Kim, A. Cmelak, M. Rotman, M. Machtay, J. Ensley, K. Chao, C. Schultz, N. Lee, K. Fu (2004)
Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck.The New England journal of medicine, 350 19
P. Huguenin, K. Beer, A. Allal, K. Rufibach, Corinne Friedli, Jacques Davis, B. Pestalozzi, S. Schmid, A. Thöni, M. Ozsahin, J. Bernier, M. Töpfer, R. Kann, U. Meier, P. Thum, S. Bieri, M. Notter, N. Lombriser, C. Glanzmann (2004)
Concomitant cisplatin significantly improves locoregional control in advanced head and neck cancers treated with hyperfractionated radiotherapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22 23
E. Cohen, F. Rosen, W. Stadler, W. Recant, K. Stenson, D. Huo, E. Vokes (2003)
Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 21 10
A. Pacagnella P.L. Zorat (2004)
Randomized phase III trial of neoadjuvant chemotherapy in head and neck cancer: 10-year follow-upJ Natl Cancer Inst, 96
Y. Pointreau, P. Garaud, S. Chapet, C. Sire, C. Tuchais, J. Tortochaux, S. Faivre, S. Guerrif, M. Alfonsi, G. Calais (2009)
Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation.Journal of the National Cancer Institute, 101 7
M. al-Sarraf, B. Metch, J. Kish, J. Ensley, J. Rinehart, D. Schuller, C. Coltman (1987)
Platinum analogs in recurrent and advanced head and neck cancer: a Southwest Oncology Group and Wayne State University Study.Cancer treatment reports, 71 7-8
B. Murphy (2005)
Topoisomerases in the treatment of metastatic or recurrent squamous carcinoma of the head and neckExpert Opinion on Pharmacotherapy, 6
J. Cooper, T. Pajak, A. Forastiere, J. Jacobs, B. Campbell, S. Saxman, J. Kish, A. Cmelak, H. Kim, K. Fu (2006)
25 : Long-Term Survival Results of a Phase III Intergroup Trial (RTOG 95-01) of Surgery Followed by Radiotherapy vs. Radiochemotherapy for Resectable High Risk Squamous Cell Carcinoma of the Head And NeckInternational Journal of Radiation Oncology Biology Physics, 66
A. Jemal, R. Siegel, Elizabeth Ward, Taylor Murray, Jiaquan Xu, M. Thun (2007)
Cancer Statistics, 2007CA: A Cancer Journal for Clinicians, 57
G. Catimel, J. Vermorken, M. Clavel, P. Mulder, I. Judson, C. Sessa, M. Piccart, U. Bruntsch, J. Verweij, J. Wanders, H. Franklin, S. Kaye (1994)
A phase II study of Gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neckAnnals of Oncology, 5
D. Brizel, M. Albers, S. Fisher, R. Scher, W. Richtsmeier, V. Hárs, S. George, A. Huang, L. Prosnitz (1998)
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.The New England journal of medicine, 338 25
C. Tourneau, E. Chen (2008)
Molecularly targeted agents in the treatment of recurrent or metastatic squamous cell carcinomas of the head and neck.Hematology/oncology clinics of North America, 22 6
J. Bonner, P. Harari, J. Giralt, N. Azarnia, D. Shin, R. Cohen, Christopher Jones, R. Sur, D. Raben, J. Jassem, R. Ove, M. Kies, J. Baselga, H. Youssoufian, N. Amellal, E. Rowinsky, E. Rowinsky, K. Ang (2006)
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck.The New England journal of medicine, 354 6
A. Forastiere, M. Maor, R. Weber, T. Pajak, B. Glisson, A. Trotti, J. Ridge, J. Ensley, C. Chao, John Cooper (2006)
Long-term results of Intergroup RTOG 91-11: A phase III trial to preserve the larynx-Induction cisplatin/5-FU and radiation therapy versus concurrent cisplatin and radiation therapy versus radiation therapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 18_suppl
A. Orlando A. Paccagnella (1994)
Phase III trial of initial chemotherapy in stage III or IV head and neck cancers: a study by the Gruppo di Studio sui Tumori della Testa e del ColloJ Natl Cancer Inst, 86
M. al-Sarraf, M. LeBlanc, P. Giri, K. Fu, J. Cooper, T. Vuong, A. Forastiere, G. Adams, W. Sakr, D. Schuller, J. Ensley (1998)
Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 16 4
G. Anaya-Saavedra, V. Ramírez-Amador, M. Irigoyen-Camacho, C. Garcia-Cuellar, M. Guido-Jiménez, R. Méndez-Martínez, A. García-Carrancá (2008)
High association of human papillomavirus infection with oral cancer: a case-control study.Archives of medical research, 39 2
D.J. Haraf T.Y. Seiwert (2006)
A phase I study of bevacizumab (B) with fluorouracil (F) and hydroxyurea (H) with concomitant radiotherapy (X) (B-FHX) for poor prognosis head and neck cancer (HNC)Proc Am Soc Clin Oncol., 24
R. Wittes, K. Heller, V. Randolph, J. Howard, A. Vallejo, H. Farr, C. Harrold, F. Gerold, J. Shah, R. Spiro, E. Strong (1979)
cis-Dichlorodiammineplatinum(II)-based chemotherapy as initial treatment of advanced head and neck cancer.Cancer treatment reports, 63 9-10
R. Herbst, M. Arquette, D. Shin, K. Dicke, E. Vokes, N. Azarnia, W. Hong, M. Kies (2005)
Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 24
J. Moon F.P. Worden (2006)
A phase II evaluation of a 3-hour infusion of paclitaxel, cisplatin, and 5-fluorouracil in patients with advanced or recurrent squamous cell carcinoma of the head and neck: Southwest Oncology Group study 0007Cancer, 107
A. Forastiere, B. Metch, D. Schuller, J. Ensley, L. Hutchins, P. Triozzi, J. Kish, S. McClure, E. VonFeldt, S. Williamson (1992)
Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 10 8
G. Catimel, J. Vermorken, M. Clavel, P. Mulder, I. Judson, C. Sessa, M. Piccart, U. Bruntsch, J. Verweij, J. Wanders (1994)
A phase II study of Gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group.Annals of oncology : official journal of the European Society for Medical Oncology, 5 6
R. Hitt, A. Jimeno, M. Rodríguez-Pinilla, J. Rodríguez-Peralto, J. Millán, A. López-Martín, A. Brandáriz, C. Peña, H. Cortés-Funes (2004)
Phase II trial of cisplatin and capecitabine in patients with squamous cell carcinoma of the head and neck, and correlative study of angiogenic factorsBritish Journal of Cancer, 91
B. Baujat, H. Audry, J. Bourhis, A. Chan, H. Onat, D. Chua, D. Kwong, M. al-Sarraf, K. Chi, M. Hareyama, S. Leung, K. Thephamongkhol, J. Pignon (2006)
Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients.International journal of radiation oncology, biology, physics, 64 1
H. Pinto, Charlotte Jacobs (1991)
Chemotherapy for recurrent and metastatic head and neck cancer.Hematology/oncology clinics of North America, 5 4
T. Seiwert, D. Haraf, E. Cohen, K. Stenson, A. Mauer, A. Dekker, C. Bajda, R. Weichselbaum, H Chen, E. Vokes (2006)
A phase I study of bevacizumab (B) with fluorouracil (F) and hydroxyurea (H) with concomitant radiotherapy (X) (B-FHX) for poor prognosis head and neck cancer (HNC).Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 18_suppl
A. Argiris, M. Gibson, D. Heron, Ryan Smith, R. Ferris, S. Lai, Seungwon Kim, B. Branstetter, Jonas Johnson, J. Grandis (2008)
Phase II trial of neoadjuvant docetaxel (T), cisplatin (P), and cetuximab (E) followed by concurrent radiation (X), P, and E in locally advanced head and neck cancer (HNC)Journal of Clinical Oncology, 26
J. Lefebvre, D. Chevalier, B. Luboinski, A. Kirkpatrick, L. Collette, T. Sahmoud (1996)
Larynx preservation in pyriform sinus cancer: preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative Group.Journal of the National Cancer Institute, 88 13
J. Baselga, J. Trigo, J. Bourhis, J. Tortochaux, H. Cortés-Funes, R. Hitt, P. Gascón, N. Amellal, A. Harstrick, A. Eckardt (2005)
Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 24
P. Garaud null Pointreau (2009)
Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservationJ Natl Cancer Inst, 101
Christian Domenge, C. Hill, J. Lefebvre, D. Raucourt, B. Rhein, P. Wibault, P. Marandas, B. Coche-Déquéant, M. Stromboni-Luboinski, H. Sancho-garnier, B. Luboinski (2000)
Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinomaBritish Journal of Cancer, 83
E. Remenar J.B. Vermorken (2007)
Cisplatin, fluorouracil, and cetuximab in unresectable head and neck cancerN Engl J Med, 357
D. Chevalier J.L. Lefebvre (1996)
Larynx preservation in pyriform sinus cancer: Preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative GroupJ Natl Cancer Inst, 88
D. Soulières, N. Senzer, E. Vokes, M. Hidalgo, S. Agarwala, L. Siu (2004)
Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22 1
K.T. Beer K. Lindel (2001)
Human papillomavirus positive quamous cell carcinoma of the oropharynx: a radiosensitive subgroup of head and neck carcinomaCancer, 92
D. Rosenthal, David Istenmaa, E. Glatstein (1994)
A review of neoadjuvant chemotherapy for head and neck cancer: partially shrunken tumors may be both leaner and meaner.International journal of radiation oncology, biology, physics, 28 1
H. Tideman (1999)
Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck An Eastern Cooperative Oncology Group Trial (PA390)International Journal of Oral and Maxillofacial Surgery, 28
D. Rischin, J. Corry, Jennifer Smith, J. Stewart, P. Hughes, L. Peters (2002)
Excellent disease control and survival in patients with advanced nasopharyngeal cancer treated with chemoradiation.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 20 7
Charlotte Jacobs, Gary Lyman, E. Vélez‐garcía, K. Sridhar, W. Knight, H. Hochster, Lawrence Goodnough, Joanne Mortimer, L. Einhorn, L. Schacter (1992)
A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 10 2
L. Licitra, L. Locati, P. Bossi (2008)
Optimizing approaches to head and neck cancer. Metastatic head and neck cancer: new options.Annals of oncology : official journal of the European Society for Medical Oncology, 19 Suppl 7
(1991)
The Department of Veterans Affairs Laryngeal Cancer Study GroupN Engl J Med, 324
Y. Onozawa S. Zenda (2007)
Single-agent docetaxel in patients with platinumrefractory metastatic or recurrent squamous cell carcinoma of the head and neck (SCCHN)Jpn J Clin Oncol, 37
T.G. Karrison E.E. Cohen (2009)
A phase I study of erlotinib and bevacizumab for recurrent or metastatic squamous cell carcinoma of the head and neck (HNC)Lancet Oncol, 10
J. Pignon, J. Bourhis, Christian Domenge, L. Designé, O. Group (2000)
Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual dataThe Lancet, 355
D. Genet, D. Cupissol, G. Calais, P. Bontemps, H. Bourgeois, J. Dutin, M. Philippi, B. Bendahmane, M. Mallard-Carre, N. Tubiana-Mathieu (2004)
Docetaxel Plus 5-Fluorouracil in Locally Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck: A Phase II Multicenter StudyAmerican Journal of Clinical Oncology, 27
A. Forastiere, H. Goepfert, M. Maor, T. Pajak, R. Weber, W. Morrison, B. Glisson, A. Trotti, J. Ridge, C. Chao, G. Peters, Ding‐Jen Lee, A. Leaf, J. Ensley, J. Cooper (2003)
Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer.The New England journal of medicine, 349 22
J.B. Vermorken M. Clavel (1994)
Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head and Neck Cancer Cooperative GroupAnn Oncol, 5
M. Gibson, Yi Li, B. Murphy, M. Hussain, R. Deconti, J. Ensley, A. Forastiere (2005)
Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): an intergroup trial of the Eastern Cooperative Oncology Group.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 15
X. Pivot, E. Raymond, B. Laguerre, M. Degardin, L. Cals, J. Armand, J. Lefebvre, D. Gédouin, V. Ripoche, L. Kayitalire, C. Niyikiza, R. Johnson, J. Latz, M. Schneider (2001)
Pemetrexed disodium in recurrent locally advanced or metastatic squamous cell carcinoma of the head and neckBritish Journal of Cancer, 85
E. Guardiola, F. Peyrade, L. Chaigneau, D. Cupissol, X. Tchiknavorian, E. Bompas, A. Madroszyk, P. Ronchin, M. Schneider, J. Bleuze, J. Blay, X. Pivot (2004)
Results of a randomised phase II study comparing docetaxel with methotrexate in patients with recurrent head and neck cancer.European journal of cancer, 40 14
J. Labourey, D. Cupissol, G. Calais, J. Tourani, F. Kohser, C. Borel, J. Eymard, N. Germann, N. Tubiana-Mathieu (2007)
Docetaxel Plus Gemcitabine in Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head And Neck: A Phase II Multicenter StudyAmerican Journal of Clinical Oncology, 30
S. Zenda, Y. Onozawa, N. Boku, Y. Iida, M. Ebihara, T. Onitsuka (2007)
Single-agent docetaxel in patients with platinum-refractory metastatic or recurrent squamous cell carcinoma of the head and neck (SCCHN).Japanese journal of clinical oncology, 37 7
J. Vermorken, J. Trigo, R. Hitt, P. Koralewski, E. Díaz-Rubio, F. Rolland, R. Knecht, N. Amellal, A. Schueler, J. Baselga (2007)
Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 25 16
J. Bentzen, H. Hansen (2007)
Phase II analysis of paclitaxel and capecitabine in the treatment of recurrent or disseminated squamous cell carcinoma of the head and neck regionHead & Neck, 29
J. Lefebvre, D. Chevalier, B. Luboinski, L. Traissac, G. Andry, D. Raucourt, L. Collette, J. Bernier (2004)
Is laryngeal preservation (LP) with induction chemotherapy (ICT) safe in the treatment of hypopharyngeal SCC? Final results of the phase III EORTC 24891 trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22 14_suppl
E. Vokes, E. Cohen, A. Mauer, T. Karrison, Stuart Wong, L. Skoog-Sluman, M. Kozloff, J. Dancey, A. Dekker (2005)
A phase I study of erlotinib and bevacizumab for recurrent or metastatic squamous cell carcinoma of the head and neck (HNC)Journal of Clinical Oncology, 23
W.H. Westra C. Fakhry (2008)
Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trialJ Natl Cancer Inst, 100
E. Vokes, R. Weichselbaum, S. Lippman, Waun Hong (1993)
Head and Neck CancerThe New England journal of medicine, 328 3
Abstract Head and neck squamous cell cancer (HNSCC) is most commonly a tobacco-related disease, affecting nearly 600,000 people worldwide each year. For decades, HNSCC has been treated successfully with multimodality treatments including, surgery, radiation, and chemotherapy, though the ‘perfect’ treatment paradigm remains elusive. This review will discuss a number of clinical trials, comparing various combinations of chemotherapy and the settings in which they are most successful. Promising research and recent data on the combination of cytotoxic chemotherapy with new biological agents indicate chemotherapy plays a critical role in treatment of HNSCC and will only continue to improve.
Indian Journal of Surgical Oncology – Springer Journals
Published: Apr 1, 2010
Keywords: surgical oncology; oncology; surgery
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.