Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Three-dimensional matrixes of natural and synthetic origin for cell biotechnology

Three-dimensional matrixes of natural and synthetic origin for cell biotechnology The review describes the classification, analysis, characteristics, and prospects of the application of various types of matrixes, of natural or synthetic origin, for cell biotechnology. Particular attention is paid to three-dimensional structures designed on the basis of extracellular matrix (ECM) components with multipotent mesenchymal stromal cells (MMSCs). In particular, the authors previously obtained cell populations with a phenotype similar to MMSCs from farm animal bone marrow (BM) and adipose tissues (AT). A comparative analysis of the properties and features of the derived cellular populations was performed. It was established that MMSCs isolated from BM and AT were capable of forming fatty, bone, and muscle tissue cells when cultured in induction media in vitro. Therefore, the production of farm animal muscle tissue analogs by myogenesis via three-dimensional MMSC cultivation on a porous matrix is a promising research direction for the needs of regenerative medicine, veterinary medicine, and cell and food biotechnology. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Biochemistry and Microbiology Springer Journals

Three-dimensional matrixes of natural and synthetic origin for cell biotechnology

Loading next page...
 
/lp/springer-journals/three-dimensional-matrixes-of-natural-and-synthetic-origin-for-cell-s2TKKELRkJ

References (68)

Publisher
Springer Journals
Copyright
Copyright © 2015 by Pleiades Publishing, Inc.
Subject
Life Sciences; Biochemistry, general; Microbiology; Medical Microbiology
ISSN
0003-6838
eISSN
1608-3024
DOI
10.1134/S0003683815090082
Publisher site
See Article on Publisher Site

Abstract

The review describes the classification, analysis, characteristics, and prospects of the application of various types of matrixes, of natural or synthetic origin, for cell biotechnology. Particular attention is paid to three-dimensional structures designed on the basis of extracellular matrix (ECM) components with multipotent mesenchymal stromal cells (MMSCs). In particular, the authors previously obtained cell populations with a phenotype similar to MMSCs from farm animal bone marrow (BM) and adipose tissues (AT). A comparative analysis of the properties and features of the derived cellular populations was performed. It was established that MMSCs isolated from BM and AT were capable of forming fatty, bone, and muscle tissue cells when cultured in induction media in vitro. Therefore, the production of farm animal muscle tissue analogs by myogenesis via three-dimensional MMSC cultivation on a porous matrix is a promising research direction for the needs of regenerative medicine, veterinary medicine, and cell and food biotechnology.

Journal

Applied Biochemistry and MicrobiologySpringer Journals

Published: Oct 31, 2015

There are no references for this article.