Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

The validation and application of the technicon H*1 for the complete automated evaluation of laboratory animal haematology

The validation and application of the technicon H*1 for the complete automated evaluation of... The Technicon H*1 has been used in human medicine for many years. Recently, Technicon have modified the instrument's software to allow the evaluation of rodent and dog blood samples. This article presents the results of the validation studies we performed with the Technicon H*1 for use with animal blood and describes aspects of precision, accuracy, sample storage and the ability to detect abnormal haematology profiles. Our conclusions indicate that the Technicon H*1 is a reliable instrument capable of producing a complete blood count together with an accurate white cell differential count for both rodent and dog samples. The parameters it now makes available have improved our diagnostic efficiency, both in terms of turnaround time for results and the early identification of an adverse drug reaction in our animal toxicology studies. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Comparative Clinical Pathology Springer Journals

The validation and application of the technicon H*1 for the complete automated evaluation of laboratory animal haematology

Davies, D.; Fisher, G.
Comparative Clinical Pathology , Volume 1 (2) – Sep 22, 2004
Download PDF
15 pages

Loading next page...
 
/lp/springer-journals/the-validation-and-application-of-the-technicon-h-1-for-the-complete-gGnsytd2vl

References (1)

Publisher
Springer Journals
Copyright
Copyright © 1991 by Springer-Verlag London Limited
Subject
Medicine & Public Health; Pathology; Hematology; Oncology
eISSN
1433-2973
DOI
10.1007/BF00422879
Publisher site
See Article on Publisher Site

Abstract

The Technicon H*1 has been used in human medicine for many years. Recently, Technicon have modified the instrument's software to allow the evaluation of rodent and dog blood samples. This article presents the results of the validation studies we performed with the Technicon H*1 for use with animal blood and describes aspects of precision, accuracy, sample storage and the ability to detect abnormal haematology profiles. Our conclusions indicate that the Technicon H*1 is a reliable instrument capable of producing a complete blood count together with an accurate white cell differential count for both rodent and dog samples. The parameters it now makes available have improved our diagnostic efficiency, both in terms of turnaround time for results and the early identification of an adverse drug reaction in our animal toxicology studies.

Journal

Comparative Clinical Pathology – Springer Journals

Published: Sep 22, 2004

There are no references for this article.