Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

The Role of Macrolides in Chronic Rhinosinusitis (CRSsNP and CRSwNP)

The Role of Macrolides in Chronic Rhinosinusitis (CRSsNP and CRSwNP) Curr Allergy Asthma Rep (2017) 17: 30 DOI 10.1007/s11882-017-0696-z RHINOSINUSITIS (J MULLOL, SECTION EDITOR) The Role of Macrolides in Chronic Rhinosinusitis (CRSsNP and CRSwNP) 1 2,3 4 Gretchen M. Oakley & Richard J. Harvey & Valerie J. Lund Published online: 20 April 2017 Springer Science+Business Media New York 2017 . . . Abstract Keywords Macrolide Chronic rhinosinusitis Sinusitis Purpose of Review We assess the literature on the pharmaco- Non-eosinophilic Medical management kinetics, indications, important considerations, and effective- ness of long-term, low-dose macrolide antibiotics in chronic rhinosinusitis (CRS). Introduction Recent Findings The key to effective implementation of macrolide therapy in CRS is appropriate patient selection. Macrolide antibiotics have gained initial popularity for their Macrolides have demonstrated the most benefit in Th1- role in the treatment of chronic rhinosinusitis (CRS), based on mediated non-eosinophilic CRS when used for durations of their success in a subtype of lower airway inflammation. at least 3 months. Erythromycin was the first in the macrolide family, discovered Summary Macrolide antibiotics have demonstrated great ben- in a soil sample in the Philippines in the 1950s, and since then efit when used for their anti-inflammatory or immunomodu- synthetic variations have been developed with better gut ab- latory properties, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Allergy and Asthma Reports Springer Journals

The Role of Macrolides in Chronic Rhinosinusitis (CRSsNP and CRSwNP)

Download PDF
10 pages

Loading next page...
 
/lp/springer-journals/the-role-of-macrolides-in-chronic-rhinosinusitis-crssnp-and-crswnp-4sDRD9vsul

References (85)

Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer Science+Business Media New York
Subject
Medicine & Public Health; Allergology
ISSN
1529-7322
eISSN
1534-6315
DOI
10.1007/s11882-017-0696-z
pmid
28429305
Publisher site
See Article on Publisher Site

Abstract

Curr Allergy Asthma Rep (2017) 17: 30 DOI 10.1007/s11882-017-0696-z RHINOSINUSITIS (J MULLOL, SECTION EDITOR) The Role of Macrolides in Chronic Rhinosinusitis (CRSsNP and CRSwNP) 1 2,3 4 Gretchen M. Oakley & Richard J. Harvey & Valerie J. Lund Published online: 20 April 2017 Springer Science+Business Media New York 2017 . . . Abstract Keywords Macrolide Chronic rhinosinusitis Sinusitis Purpose of Review We assess the literature on the pharmaco- Non-eosinophilic Medical management kinetics, indications, important considerations, and effective- ness of long-term, low-dose macrolide antibiotics in chronic rhinosinusitis (CRS). Introduction Recent Findings The key to effective implementation of macrolide therapy in CRS is appropriate patient selection. Macrolide antibiotics have gained initial popularity for their Macrolides have demonstrated the most benefit in Th1- role in the treatment of chronic rhinosinusitis (CRS), based on mediated non-eosinophilic CRS when used for durations of their success in a subtype of lower airway inflammation. at least 3 months. Erythromycin was the first in the macrolide family, discovered Summary Macrolide antibiotics have demonstrated great ben- in a soil sample in the Philippines in the 1950s, and since then efit when used for their anti-inflammatory or immunomodu- synthetic variations have been developed with better gut ab- latory properties,

Journal

Current Allergy and Asthma Reports – Springer Journals

Published: Apr 20, 2017

There are no references for this article.