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Nucl Med Mol Imaging (2014) 48:130–136 DOI 10.1007/s13139-013-0248-y ORIGINAL ARTICLE The Role of F-FDG PET/CT in Assessing Therapy Response in Cervix Cancer after Concurrent Chemoradiation Therapy Jiyoun Choi & Hyun Jeong Kim & Yong Hyu Jeong & Jae-Hoon Lee & Arthur Cho & Mijin Yun & Jong Doo Lee & Yong Bae Kim & Young Tae Kim & Won Jun Kang Received: 1 July 2013 /Revised: 16 October 2013 /Accepted: 22 October 2013 /Published online: 15 November 2013 Korean Society of Nuclear Medicine 2013 Abstract Results Of 136 patients, 124 showed complete response on Purpose To determine whether persisting cervical further follow-up studies and 12 were confirmed to have fluorodeoxyglucose (FDG) uptake after concurrent chemora- residual tumor. The post-treatment SUVmax and pre-/post- diotherapy (CCRT) for cervical cancer can reflect residual treatment SUVmean of complete responders were significant- malignancy. ly lower than those of patients with residual tumor: 2.5±0.8 Methods F-FDG PET/CT was performed before and after and 7.2±4.2/1.9±0.7 for complete responders and 5.7±2.6 CCRT in 136 patients with cervical cancer. The maximum and 12.8±6.9/3.7±0.7 for patients with residual tumor (p < and mean standardized uptake values (SUVmax and 0.05). The pre-treatment SUVmax and pre-/post-treatment SUVmean) were recorded from PET/CT
Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Nov 15, 2013
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