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Cristian Saborido, M. Mossio, Á. Moreno (2011)
Biological Organization and Cross-Generation FunctionsThe British Journal for the Philosophy of Science, 62
Nicholas Binney (2018)
The function of the heart is not obvious.Studies in history and philosophy of biological and biomedical sciences, 68-69
Justin Garson (2017)
Against Organizational FunctionsPhilosophy of Science, 84
Marc Artiga, Manolo Martínez (2015)
The Organizational Account of Function is an Etiological Account of FunctionActa Biotheoretica, 64
U. Alon (2007)
Network motifs: theory and experimental approachesNature Reviews Genetics, 8
A. Grandpierre, M. Kafatos (2012)
Biological Autonomy
Pavel Zhuravlev, G. Papoian (2010)
Protein functional landscapes, dynamics, allostery: a tortuous path towards a universal theoretical frameworkQuarterly Reviews of Biophysics, 43
K. Ruiz-Mirazo, F. Mavelli (2008)
On the way towards 'basic autonomous agents': Stochastic simulations of minimal lipid-peptide cellsBio Systems, 91 2
Argyris Arnellos, Á. Moreno (2012)
HOW FUNCTIONAL DIFFERENTIATION ORIGINATED IN PREBIOTIC EVOLUTION, 20
Leonardo Bich, M. Mossio, K. Ruiz-Mirazo, Á. Moreno (2016)
Biological regulation: controlling the system from withinBiology & Philosophy, 31
Johannes Jaeger, J. Reinitz (2006)
On the dynamic nature of positional information.BioEssays : news and reviews in molecular, cellular and developmental biology, 28 11
A. Goldstein (2011)
A Defense of Achinstein's Pragmatism about Explanation
U. Alon (2019)
An introduction to systems biology : design principles of biological circuits
P. Atkins (1984)
The Second Law
Sandra Mitchell (2009)
Unsimple Truths: Science, Complexity, and Policy
Cristian Saborido, Á. Moreno (2015)
Biological pathology from an organizational perspectiveTheoretical Medicine and Bioethics, 36
M. Mossio, Cristian Saborido, Á. Moreno (2009)
An Organizational Account of Biological FunctionsThe British Journal for the Philosophy of Science, 60
K. Ruiz-Mirazo, Á. Moreno (2012)
Autonomy in evolution: from minimal to complex lifeSynthese, 185
G. Müller (2007)
Evo–devo: extending the evolutionary synthesisNature Reviews Genetics, 8
Maël Montévil, M. Mossio (2015)
Biological organisation as closure of constraints.Journal of theoretical biology, 372
SA Kauffman (2000)
Investigations
K. Ruiz-Mirazo, Á. Moreno (2004)
Basic Autonomy as a Fundamental Step in the Synthesis of LifeArtificial Life, 10
D. Rigden (2009)
From Protein Structure to Function with Bioinformatics
M. Mossio, Cristian Saborido (2016)
Functions, Organization and Etiology: A Reply to Artiga and MartinezActa Biotheoretica, 64
F. Varela (1979)
Principles of biological autonomy
Marc Artiga (2011)
Re-organizing organizational accounts of functionAppl. Ontology, 6
G. Bowman, V. Pande (2010)
Protein folded states are kinetic hubsProceedings of the National Academy of Sciences, 107
Á. Moreno (2000)
Closure, Identity, and the Emergence of Formal CausationAnnals of the New York Academy of Sciences, 901
Justin Garson (2016)
A Critical Overview of Biological Functions
W. Wimsatt (2007)
Re-Engineering Philosophy for Limited Beings: Piecewise Approximations to Reality
Gregory Morgan (2011)
Philosophy of science matters : the philosophy of Peter Achinstein
J. Griesemer (2015)
The enduring value of Gánti's chemoton model and life criteria: Heuristic pursuit of exact theoretical biology.Journal of theoretical biology, 381
P. Achinstein (1984)
The Pragmatic Character of ExplanationPSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association, 1984
Alberto Pérez, Arijit Roy, Koushik Kasavajhala, A. Wagaman, Ken Dill, J. MacCallum (2014)
Extracting representative structures from protein conformational ensemblesProteins: Structure, 82
Mark Wilson (2006)
Wandering significance : an essay on conceptual behavior
We critique the organizational account of biological functions by showing how its basis in the closure of constraints fails to be objective. While the account treats constraints as objective features of physical systems, the number and relationship of potential constraints are subject to potentially arbitrary redescription by investigators. For example, we show that self-maintaining systems such as candle flames can realize closure on a more thorough analysis of the case, contradicting the claim that these “simple” systems lack functional organization. This also raises problems for Moreno and Mossio’s associated theory of biological autonomy, which asserts that living beings are distinguished by their possession of a closed system of constraints that channel and regulate their metabolic processes.
Acta Biotheoretica – Springer Journals
Published: Jun 13, 2020
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