Access the full text.
Sign up today, get DeepDyve free for 14 days.
V. Korobov, T. Polyudova, L. Filatova, L. Lemkina, N. Pan’kova (2010)
Activation of autolytic activity of Staphylococcus epidermidis 33 by a low-molecular weight cationic peptide warnerinMicrobiology, 79
G. Bierbaum, H. Sahl (1985)
Induction of autolysis of staphylococci by the basic peptide antibiotics Pep 5 and nisin and their influence on the activity of autolytic enzymesArchives of Microbiology, 141
L. Formentini, M. Sánchez-Aragó, L. Sánchez-Cenizo, J. Cuezva (2012)
The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response.Molecular cell, 45 6
KARL-DIETER ENTIANt (1989)
Nisin, a peptide antibiotic: cloning and sequencing of the nisA gene and posttranslational processing of its peptide productJournal of Bacteriology, 171
F. Götz, S. Perconti, Peter Popella, R. Werner, M. Schlag (2014)
Epidermin and gallidermin: Staphylococcal lantibiotics.International journal of medical microbiology : IJMM, 304 1
T. Polyudova, L. Lemkina, G. Likhatskaya, V. Korobov (2017)
Optimization of production conditions and 3D-structure modeling of novel antibacterial peptide of lantibiotic familyApplied Biochemistry and Microbiology, 53
J. Petersen, A. Boysen, Lotte Fogh, Kathrine Tabermann, T. Kofoed, A. King, P. Schrotz-King, M. Hansen (2009)
Identification and characterization of a bioactive lantibiotic produced by Staphylococcus warneriBiological Chemistry, 390
S. Asaduzzaman, Jun-ichi Nagao, H. Iida, T. Zendo, J. Nakayama, K. Sonomoto (2009)
Nukacin ISK-1, a Bacteriostatic LantibioticAntimicrobial Agents and Chemotherapy, 53
Alexis Simons, Kamel Alhanout, R. Duval (2020)
Bacteriocins, Antimicrobial Peptides from Bacterial Origin: Overview of Their Biology and Their Impact against Multidrug-Resistant BacteriaMicroorganisms, 8
L. Kononova, L. Filatova, D. Eroshenko, V. Korobov, V. Korobov (2017)
Suppression of development of vancomycin-resistant Staphylococcus epidermidis by low-molecular-weight cationic peptides of the lantibiotic familyMicrobiology, 86
M. Yasir, Debarun Dutta, M. Willcox (2019)
Mode of action of the antimicrobial peptide Mel4 is independent of Staphylococcus aureus cell membrane permeabilityPLoS ONE, 14
M. Shimoda, K. Ohki, Y. Shimamoto, O. Kohashi (1995)
Morphology of defensin-treated Staphylococcus aureusInfection and Immunity, 63
M. Lobritz, Peter Belenky, C. Porter, Arnaud Gutierrez, Jason Yang, Eric Schwarz, D. Dwyer, Ahmad Khalil, J. Collins (2015)
Antibiotic efficacy is linked to bacterial cellular respirationProceedings of the National Academy of Sciences, 112
M. Yasir (2019)
10.1371/journal.pone.0215703PLoS One, 14
M. Wasil, B. Halliwell, M. Grootveld, C. Moorhouse, D. Hutchison, H. Baum (1987)
The specificity of thiourea, dimethylthiourea and dimethyl sulphoxide as scavengers of hydroxyl radicals. Their protection of alpha 1-antiproteinase against inactivation by hypochlorous acid.The Biochemical journal, 243 3
G. Bierbaum, H. Sahl (2009)
Lantibiotics: mode of action, biosynthesis and bioengineering.Current pharmaceutical biotechnology, 10 1
Christopher Lacriola, Shaun Falk, B. Weisblum (2012)
Screen for Agents That Induce Autolysis in Bacillus subtilisAntimicrobial Agents and Chemotherapy, 57
A. Penyige, János Matkó, János Matkó, E. Deák, A. Bodnár, G. Barabás (2002)
Depolarization of the membrane potential by β-lactams as a signal to induce autolysisBiochemical and Biophysical Research Communications, 290
M. Kemper, M. Urrutia, T. Beveridge, A. Koch, R. Doyle (1993)
Proton motive force may regulate cell wall-associated enzymes of Bacillus subtilisJournal of Bacteriology, 175
V. Korobov, A. Titova, L. Lemkina, T. Polyudova, N. Pan’kova (2005)
The dependence of the antibacterial effect of the polycationic peptide warnerin on the energy state of target cellsMicrobiology, 74
R. Bonelli, T. Schneider, H. Sahl, I. Wiedemann (2006)
Insights into In Vivo Activities of Lantibiotics from Gallidermin and Epidermin Mode-of-Action StudiesAntimicrobial Agents and Chemotherapy, 50
S. Heilbronner, B. Krismer, H. Brötz-Oesterhelt, A. Peschel (2021)
The microbiome-shaping roles of bacteriocinsNature Reviews Microbiology, 19
V. Korobov, L. Lemkina, T. Polyudova, V. Akimenko (2010)
Isolation and characterization of a new low-molecular antibacterial peptide of the lantibiotics familyMicrobiology, 79
M. Abrudan, Fokko Smakman, Ard Grimbergen, S. Westhoff, E. Miller, G. Wezel, D. Rozen (2015)
Socially mediated induction and suppression of antibiosis during bacterial coexistenceProceedings of the National Academy of Sciences, 112
D. Dwyer, Peter Belenky, Jason Yang, I. MacDonald, Jeffrey Martell, N. Takahashi, Clement Chan, M. Lobritz, D. Braff, Eric Schwarz, Jonathan Ye, Mekhala Pati, M. Vercruysse, Paul Ralifo, K. Allison, Ahmad Khalil, A. Ting, G. Walker, J. Collins (2014)
Antibiotics induce redox-related physiological alterations as part of their lethalityProceedings of the National Academy of Sciences, 111
Raja Biswas, R. Martinez, Nadine Göhring, M. Schlag, Michaele Josten, Guoqing Xia, F. Hegler, Cordula Gekeler, Anne-Kathrin Gleske, F. Götz, H. Sahl, A. Kappler, A. Peschel (2012)
Proton-Binding Capacity of Staphylococcus aureus Wall Teichoic Acid and Its Role in Controlling Autolysin ActivityPLoS ONE, 7
G. Bierbaum, C. Szekat, M. Josten, C. Heidrich, C. Kempter, G. Jung, H. Sahl (1996)
Engineering of a novel thioether bridge and role of modified residues in the lantibiotic Pep5Applied and Environmental Microbiology, 62
Elaine Meade, M. Slattery, M. Garvey (2020)
Bacteriocins, Potent Antimicrobial Peptides and the Fight against Multi Drug Resistant Species: Resistance Is Futile?Antibiotics, 9
T. Danevčič, Maja Vezjak, Maja Tabor, M. Zorec, D. Stopar (2016)
Prodigiosin Induces Autolysins in Actively Grown Bacillus subtilis CellsFrontiers in Microbiology, 7
Evidence of membranotropic activity of the lantibiotic warnerin was obtained for warnerin-sensitive bacteria Staphylococcus cohnii VKM-3165. Warnerin attack led to increased bacterial respiratory activity and accumulation of reactive oxygen species resulting in the death of staphylococci. Warnerin caused dissipation of the transmembrane potential with release of potassium ions and ATP from the cells. Dissipation of the potential resulted in activation of bacterial autolysis, which depends on the value of the electrical component of the membrane potential. ΔΨ dissipation in the presence of valinomycin, a potassium transporter, almost neutralized the activation of the peptidoglycan hydrolase complex by warnerin. Electron microscopy of bacterial internal structure and scanning of the surface of warnerin-attacked cells of S. cohnii VKM-3165 confirmed the depth and irreversibility of warnerin action.
Microbiology – Springer Journals
Published: Apr 1, 2022
Keywords: antibacterial activity; autolysis activation; lantibiotics; membranotropic activity; mechanism of action
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.