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References (4)
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(1991)
Leucocyte counts in peripheral blood and bone marrow as an aid to the differential diagnosis of dysmaturity and infection in newborn foals -
C. Rozman (1983)
Bone marrow biopsy.Haematologia, 16 1-4
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NC Jain (1986)
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JV Dacie, SM Lewis (1984)
Practical haematology
- Publisher
- Springer Journals
- Copyright
- Copyright © 1991 by Springer-Verlag London Limited
- Subject
- Medicine & Public Health; Pathology; Hematology; Oncology
- eISSN
- 1433-2973
- DOI
- 10.1007/BF00422880
- Publisher site
- See Article on Publisher Site
Abstract
Some acute conditions, whether naturally occurring or induced during the course of a toxicity study, lead to a series of dynamic changes in the bone marrow. These are frequently monitored by the use of the myeloid:erythroid ratio (M:E ratio). However, in the early stages of an acute reaction, the increase in numbers of primitive and early cells, stimulated by the reaction, is frequently counterbalanced by the release of mature or nearly mature cells from the marrow to their appropriate active sites, thus leaving the M:E ratio unchanged, or even apparently moving in the ‘wrong’ direction'.
Journal
Comparative Clinical Pathology – Springer Journals
Published: Sep 22, 2004