Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

The current TNM classification of breast carcinomas: Controversial issues in early breast cancer

The current TNM classification of breast carcinomas: Controversial issues in early breast cancer The TNM is the most widely used staging system for malignant disease. Its seventh edition has been updated in several respects, but there still remain controversial issues requiring further improvement. The current review highlights the items related to early breast cancer. It deals separately with contradictions found in the online resources, those related to the different categories, the stages, grade and finally it places the TNM in the milieu of biological markers often used to tailor individual patient treatment. Although TNM has lost its nearly unique role in assessing patient risk and in selecting systemic therapy for breast cancer, it is still of importance in reflecting the anatomic extent of disease in a categorical way, selecting surgical treatment and comparing similar tumours of different extent. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png memo - Magazine of European Medical Oncology Springer Journals

The current TNM classification of breast carcinomas: Controversial issues in early breast cancer

Download PDF
5 pages

Loading next page...
 
/lp/springer-journals/the-current-tnm-classification-of-breast-carcinomas-controversial-3UPVxjsU81
Publisher
Springer Journals
Copyright
Copyright © 2011 by Springer-Verlag
Subject
Medicine & Public Health; Medicine/Public Health, general; Oncology
ISSN
1865-5041
eISSN
1865-5076
DOI
10.1007/s12254-011-0280-5
Publisher site
See Article on Publisher Site

Abstract

The TNM is the most widely used staging system for malignant disease. Its seventh edition has been updated in several respects, but there still remain controversial issues requiring further improvement. The current review highlights the items related to early breast cancer. It deals separately with contradictions found in the online resources, those related to the different categories, the stages, grade and finally it places the TNM in the milieu of biological markers often used to tailor individual patient treatment. Although TNM has lost its nearly unique role in assessing patient risk and in selecting systemic therapy for breast cancer, it is still of importance in reflecting the anatomic extent of disease in a categorical way, selecting surgical treatment and comparing similar tumours of different extent.

Journal

memo - Magazine of European Medical Oncology – Springer Journals

Published: Oct 13, 2011

References

  • UICC TNM classification of malignant tumours
  • AJCC Cancer Staging Handbook: from the AJCC Cancer Staging Manual
  • AJCC Cancer Staging Manual
  • TNM supplement: a commentary on uniform use
  • Solid papillary carcinoma of the breast. A form of intraductal carcinoma with endocrine differentiation frequently associated with mucinous carcinoma
    Maluf, HM; Koerner, FC
  • Intracystic papillary carcinomas of the breast: a reevaluation using a panel of myoepithelial cell markers
    Collins, LC; Carlo, VP; Hwang, H
  • Papillary lesions of the breast: selected diagnostic and management issues
    Collins, LC; Schnitt, SJ
  • Biopsy interpretation of the breast
    Schnitt, SJ; Collins, LC
  • Rosen's breast pathology
    Rosen, PP
  • Intracystic (encysted) papillary carcinoma of the breast: a clinical, pathological, and immunohistochemical study
    Leal, C; Costa, I; Fonseca, D
  • Clinical relevance of the distribution of the lesions in 500 consecutive breast cancer cases documented in large-format histologic sections
    Tot, T
  • Practical breast pathology
    Tot, T; Tabár, L; Dean, P
  • Modeling the effect of tumor size in early breast cancer
    Verschraegen, C; Vinh-Hung, V; Cserni, G
  • Breast cancer – The art and science of early detection with mammography: perception, interpretation, histopathologic correlation
    Tabar, L; Tot, T; Dean, PB
  • Metastatic capacity of multifocal breast carcinomas: extensive tumors versus tumors of limited extent
    Tot, T
  • Multicentric and multifocal versus unifocal breast cancer: is the tumor-node-metastasis classification justified?
    Weissenbacher, TM; Zschage, M; Janni, W
  • Improved axillary staging of breast cancer with sentinel lymphadenectomy
    Giuliano, AE; Dale, PS; Turner, RR
  • Pathological work-up of sentinel lymph nodes in breast cancer. Review of current data to be considered for the formulation of guidelines
    Cserni, G; Amendoeira, I; Apostolikas, N
  • Pathological evaluation of sentinel lymph nodes
    Cserni, G
  • Comparative evaluation of an extensive histopathologic examination and real-time reverse-transcription-polymerase chain reaction assay for mammaglobin and cytokeratin 19 on axillary sentinel lymph nodes of breast carcinoma patients
    Viale, G; Dell'Orto, P; Biasi, MO
  • Intra-operative rapid diagnostic method based on CK19 mRNA expression for the detection of lymph node metastases in breast cancer
    Visser, M; Jiwa, M; Horstman, A
  • Lymph node micrometastases from breast carcinoma: reviewing the dilemma
    Dowlatshahi, K; Fan, M; Snider, HC
  • The number of positive nodes and the ratio of positive to excised nodes are significant predictors of survival in women with micrometastatic node-positive breast cancer
    Truong, PT; Vinh-Hung, V; Cserni, G
  • Minimal axillary lymph node involvement in breast cancer has different prognostic implications according to the staging procedure
    Montagna, E; Viale, G; Rotmensz, N
  • Pathological prognostic factors in breast cancer. IV: Should you be a typer or a grader? A comparative study of two histological prognostic features in operable breast carcinoma
    Pereira, H; Pinder, SE; Sibbering, DM
  • World Health Organization classification of tumours
    Tavassoli, FA; Devilee, P
  • Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999
    Fitzgibbons, PL; Page, DL; Weaver, D
  • Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009
    Goldhirsch, A; Ingle, JN; Gelber, RD
  • Rethinking TNM: breast cancer TNM classification for treatment decision-making and research
    Veronesi, U; Viale, G; Rotmensz, N
  • Breast cancer classification: time for a change
    Veronesi, U; Zurrida, S; Goldhirsch, A