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Oncol Ther (2017) 5:31–40 DOI 10.1007/s40487-016-0037-8 ORIGINAL RESEARCH The Cost Impact of Lenalidomide for Newly Diagnosed Multiple Myeloma in the EU5 . . . Steve Schey Luis Felipe Casado Montero Chloe Stengel-Tosetti Craig J. Gibson Sujith Dhanasiri Received: October 24, 2016 / Published online: January 3, 2017 The Author(s) 2016. This article is published with open access at Springerlink.com on treatment duration and time to progression ABSTRACT (TTP) (taken from trial data). We compared a Introduction: Lenalidomide is an active agent baseline scenario (of current lenalidomide that was approved for use in the EU in 2015 as a uptake) with two alternative future scenarios. first-line therapy for previously untreated, Future Scenario A used an increased uptake of non-transplant eligible multiple myeloma first-line lenalidomide: up to 50% in Year 5. patients. Our objective was to assess the cost Future Scenario B was similar to the baseline, impact of lenalidomide when selected as a but included a 20% increased uptake of the first-line treatment for transplant-ineligible triple therapy regimen, carfilzomib, patients in France, Germany, Italy, Spain, and lenalidomide, and dexamethasone (KRd) at the United Kingdom (EU5). second line. Methods: We developed a cost-impact model of Results: Compared to alternative first-line care
Oncology and Therapy – Springer Journals
Published: Jan 3, 2017
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