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Temporal Regulation by Innate Type 2 Cytokines in Food Allergies

Temporal Regulation by Innate Type 2 Cytokines in Food Allergies Curr Allergy Asthma Rep (2016) 16: 75 DOI 10.1007/s11882-016-0656-z ALLERGIES AND THE ENVIRONMENT (M HERNANDEZ, SECTION EDITOR) Temporal Regulation by Innate Type 2 Cytokines in Food Allergies 1 1 2,3 Michelle T. Graham & Sandra Andorf & Jonathan M. Spergel & 4,5 1 Talal A. Chatila & Kari C. Nadeau Published online: 22 October 2016 Springer Science+Business Media New York 2016 Abstract also review existing evidence of the contribution of other Purpose of Review Food allergies (FAs) are a growing epi- atopic diseases to FA pathogenesis and whether FA symptoms demic in western countries with poorly defined etiology. overlap with other atopic diseases. Defined as an adverse immune response to common food allergens, FAs present heterogeneously as a single- or multi- . . . . organ response that ranges in severity from localized hives Keywords TSLP IL-33 IL-25 Food allergies and angioedema to systemic anaphylaxis. IgE-mediated ILC2s Recent Findings Current research focusing on epithelial- derived cytokines contends that temporal regulation by these factors impact initial sensitization and persistence of FA re- sponses upon repeated food allergen exposure. Mechanistic Introduction understanding of FA draws insight from a myriad of atopic conditions studied in humans and modeled in mice. The epithelium http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Allergy and Asthma Reports Springer Journals

Temporal Regulation by Innate Type 2 Cytokines in Food Allergies

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References (68)

Publisher
Springer Journals
Copyright
Copyright © 2016 by Springer Science+Business Media New York
Subject
Medicine & Public Health; Allergology
ISSN
1529-7322
eISSN
1534-6315
DOI
10.1007/s11882-016-0656-z
pmid
27771884
Publisher site
See Article on Publisher Site

Abstract

Curr Allergy Asthma Rep (2016) 16: 75 DOI 10.1007/s11882-016-0656-z ALLERGIES AND THE ENVIRONMENT (M HERNANDEZ, SECTION EDITOR) Temporal Regulation by Innate Type 2 Cytokines in Food Allergies 1 1 2,3 Michelle T. Graham & Sandra Andorf & Jonathan M. Spergel & 4,5 1 Talal A. Chatila & Kari C. Nadeau Published online: 22 October 2016 Springer Science+Business Media New York 2016 Abstract also review existing evidence of the contribution of other Purpose of Review Food allergies (FAs) are a growing epi- atopic diseases to FA pathogenesis and whether FA symptoms demic in western countries with poorly defined etiology. overlap with other atopic diseases. Defined as an adverse immune response to common food allergens, FAs present heterogeneously as a single- or multi- . . . . organ response that ranges in severity from localized hives Keywords TSLP IL-33 IL-25 Food allergies and angioedema to systemic anaphylaxis. IgE-mediated ILC2s Recent Findings Current research focusing on epithelial- derived cytokines contends that temporal regulation by these factors impact initial sensitization and persistence of FA re- sponses upon repeated food allergen exposure. Mechanistic Introduction understanding of FA draws insight from a myriad of atopic conditions studied in humans and modeled in mice. The epithelium

Journal

Current Allergy and Asthma Reports – Springer Journals

Published: Oct 22, 2016

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