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Synthesis of New N-Acyl-1,2,3-triazole Chalcones and Determination of Their Antibacterial Activity

Synthesis of New N-Acyl-1,2,3-triazole Chalcones and Determination of Their Antibacterial Activity Previously unknown N-acyl derivatives of 1,2,3-triazole chalcones have been prepared by the acylation of the potassium salts of 4-(3-oxo-3-phenylprop-1-en-1-yl)-5-phenyl-1,2,3-triazolides with carboxylic acid chlorides. The introduction of the N-acyl residue into the heterocyclic moiety of 1-aryl-3-(1H-1,2,3-triazol-4-yl)prop-2-en-1-ones has been shown to afford compounds with antibacterial activity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Doklady Chemistry Springer Journals

Synthesis of New N-Acyl-1,2,3-triazole Chalcones and Determination of Their Antibacterial Activity

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References (9)

Publisher
Springer Journals
Copyright
Copyright © Pleiades Publishing, Ltd. 2020
ISSN
0012-5008
eISSN
1608-3113
DOI
10.1134/S0012500820360021
Publisher site
See Article on Publisher Site

Abstract

Previously unknown N-acyl derivatives of 1,2,3-triazole chalcones have been prepared by the acylation of the potassium salts of 4-(3-oxo-3-phenylprop-1-en-1-yl)-5-phenyl-1,2,3-triazolides with carboxylic acid chlorides. The introduction of the N-acyl residue into the heterocyclic moiety of 1-aryl-3-(1H-1,2,3-triazol-4-yl)prop-2-en-1-ones has been shown to afford compounds with antibacterial activity.

Journal

Doklady ChemistrySpringer Journals

Published: Jun 16, 2020

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