Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Synthesis of Deuterated or Tritiated Glycine and Its Methyl Ester

Synthesis of Deuterated or Tritiated Glycine and Its Methyl Ester ISSN 0012-5008, Doklady Chemistry, 2018, Vol. 483, Part 1, pp. 266–267. © Pleiades Publishing, Ltd., 2018. Original Russian Text © V.P. Shevchenko, L.A. Andreeva, I.Yu. Nagaev, N.F. Myasoedov, 2018, published in Doklady Akademii Nauk, 2018, Vol. 483, No. 2. CHEMISTRY Synthesis of Deuterated or Tritiated Glycine and Its Methyl Ester a, a a a V. P. Shevchenko *, L. A. Andreeva , I. Yu. Nagaev , and Academician N. F. Myasoedov Received April 23, 2018 Abstract—Heating glycine (Gly) and methyl glycinate (GlyOCH ) supported on 5% Pd/C or 5% Pt/C in a deuterium or tritium gas atmosphere gave the isotope-labeled products. The experiments were carried out at 180°C for 10 min. The deuterium atom inclusion under these conditions averaged up to 1.8 atoms per mole- cule for Gly and up to 1.0 atom per molecule for GlyOCH . The reaction with tritium gas gave labeled prod- ucts with a specific radioactivity of 27–31 Ci/mmol for Gly and 18 Ci/mmol for GlyOCH . DOI: 10.1134/S0012500818110071 Usually, glyprolines are deuterated and tritiated increased, the yield of Gly decreased from 30% using precursors that contain commercial dehydro- (5 min) to 15% (10 min), 10% (15 min), and 0% (30 min). proline [1–3]. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Doklady Chemistry Springer Journals

Synthesis of Deuterated or Tritiated Glycine and Its Methyl Ester

Download PDF
2 pages

Loading next page...
 
/lp/springer-journals/synthesis-of-deuterated-or-tritiated-glycine-and-its-methyl-ester-Sc4aVXAI9S

References (0)

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Springer Journals
Copyright
Copyright © 2018 by Pleiades Publishing, Inc.
Subject
Chemistry; Chemistry/Food Science, general; Industrial Chemistry/Chemical Engineering
ISSN
0012-5008
eISSN
1608-3113
DOI
10.1134/S0012500818110071
Publisher site
See Article on Publisher Site

Abstract

ISSN 0012-5008, Doklady Chemistry, 2018, Vol. 483, Part 1, pp. 266–267. © Pleiades Publishing, Ltd., 2018. Original Russian Text © V.P. Shevchenko, L.A. Andreeva, I.Yu. Nagaev, N.F. Myasoedov, 2018, published in Doklady Akademii Nauk, 2018, Vol. 483, No. 2. CHEMISTRY Synthesis of Deuterated or Tritiated Glycine and Its Methyl Ester a, a a a V. P. Shevchenko *, L. A. Andreeva , I. Yu. Nagaev , and Academician N. F. Myasoedov Received April 23, 2018 Abstract—Heating glycine (Gly) and methyl glycinate (GlyOCH ) supported on 5% Pd/C or 5% Pt/C in a deuterium or tritium gas atmosphere gave the isotope-labeled products. The experiments were carried out at 180°C for 10 min. The deuterium atom inclusion under these conditions averaged up to 1.8 atoms per mole- cule for Gly and up to 1.0 atom per molecule for GlyOCH . The reaction with tritium gas gave labeled prod- ucts with a specific radioactivity of 27–31 Ci/mmol for Gly and 18 Ci/mmol for GlyOCH . DOI: 10.1134/S0012500818110071 Usually, glyprolines are deuterated and tritiated increased, the yield of Gly decreased from 30% using precursors that contain commercial dehydro- (5 min) to 15% (10 min), 10% (15 min), and 0% (30 min). proline [1–3].

Journal

Doklady Chemistry – Springer Journals

Published: Dec 13, 2018

There are no references for this article.