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Statistical atlas of acute stroke from magnetic resonance diffusion-weighted-images of the brain

Statistical atlas of acute stroke from magnetic resonance diffusion-weighted-images of the brain This study presents a method for computing a probabilistic atlas that describes the spatial distributions of acute infarcts of the brain. The data consisted of diffusion-weighted-images (DWI) and high-resolution T1-weighted MR images rep resenting ww studies from 22 subjects. All DWI data sets contained high-intensity lesions on B-1000 maps, known from clinical history to be related to acute stroke. To compute the atlas, manually segmented infarcts on original DWI were spatially transformed and registered to a common coordinate system. This coordinate system allowed combining all lesions into a statistical atlas in the model space. As a result, the computed probabilistic map showed mild left-sided predominance of brain infarcts, which likely represents asymmetry in eloquence of brain regions. In our opinion, the statistical atlas of acute brain infarcts can facilitate computer-based detection of stroke in large image data sets. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neuroinformatics Springer Journals

Statistical atlas of acute stroke from magnetic resonance diffusion-weighted-images of the brain

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Publisher
Springer Journals
Copyright
Copyright © 2006 by Humana Press Inc.
Subject
Chemistry; Biotechnology; Engineering, general; Neurology
ISSN
1539-2791
eISSN
1559-0089
DOI
10.1385/NI:4:3:235
pmid
16943629
Publisher site
See Article on Publisher Site

Abstract

This study presents a method for computing a probabilistic atlas that describes the spatial distributions of acute infarcts of the brain. The data consisted of diffusion-weighted-images (DWI) and high-resolution T1-weighted MR images rep resenting ww studies from 22 subjects. All DWI data sets contained high-intensity lesions on B-1000 maps, known from clinical history to be related to acute stroke. To compute the atlas, manually segmented infarcts on original DWI were spatially transformed and registered to a common coordinate system. This coordinate system allowed combining all lesions into a statistical atlas in the model space. As a result, the computed probabilistic map showed mild left-sided predominance of brain infarcts, which likely represents asymmetry in eloquence of brain regions. In our opinion, the statistical atlas of acute brain infarcts can facilitate computer-based detection of stroke in large image data sets.

Journal

NeuroinformaticsSpringer Journals

Published: Apr 11, 2007

References