Access the full text.
Sign up today, get DeepDyve free for 14 days.
I. Almendros, J. Montserrat, Josep Ramírez, Marta Torres, Joaquín Durán-Cantolla, D. Navajas, Ramon Farré (2011)
Intermittent hypoxia enhances cancer progression in a mouse model of sleep apnoeaEuropean Respiratory Journal, 39
Xiaoti Lin, Weiyu Chen, F. Wei, Mingang Ying, Weidong Wei, Xiaoming Xie (2015)
Night-shift work increases morbidity of breast cancer and all-cause mortality: a meta-analysis of 16 prospective cohort studies.Sleep medicine, 16 11
A. Ieyasu, Y. Tajima, S. Shimba, H. Nakauchi, S. Yamazaki (2014)
Clock gene Bmal1 is dispensable for intrinsic properties of murine hematopoietic stem cellsJournal of Negative Results in Biomedicine, 13
S. Toffoli, C. Michiels (2008)
Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumoursThe FEBS Journal, 275
L. Guariniello, P. Vicari, K. Lee, A. Oliveira, S. Tufik (2012)
Bone marrow and peripheral white blood cells number is affected by sleep deprivation in a murine experimental modelJournal of Cellular Physiology, 227
Ali Mteyrek, E. Filipski, C. Guettier, A. Okyar, F. Lévi (2016)
Clock gene Per2 as a controller of liver carcinogenesisOncotarget, 7
Ayaka Iwamoto, Misato Kawai, M. Furuse, S. Yasuo (2014)
Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N miceChronobiology International, 31
Deepti Nair, Shelley Zhang, V. Ramesh, F. Hakim, Navita Kaushal, Yang Wang, D. Gozal (2011)
Sleep fragmentation induces cognitive deficits via nicotinamide adenine dinucleotide phosphate oxidase-dependent pathways in mouse.American journal of respiratory and critical care medicine, 184 11
S. Crotti, A. Lissoni, D. Tubiolo, S. Azzari, P. Tarsia, L. Caspani, L. Gattinoni (2012)
Artificial lung as an alternative to mechanical ventilation in COPD exacerbationEuropean Respiratory Journal, 39
F. Nieto, P. Peppard, T. Young, L. Finn, K. Hla, R. Farré (2012)
Sleep-disordered breathing and cancer mortality: results from the Wisconsin Sleep Cohort Study.American journal of respiratory and critical care medicine, 186 2
E. Filipski, F. Lévi (2009)
Circadian Disruption in Experimental Cancer ProcessesIntegrative Cancer Therapies, 8
Seohui Lee, B. Kim, Ji Kim, Kook-Lae Lee, D. Koo, H. Nam, J. Im, J. Kim, S. Koh (2017)
Obstructive sleep apnea is associated with an increased risk of colorectal neoplasia.Gastrointestinal endoscopy, 85 3
A. Ahluwalia, Tarnawski As (2012)
Critical role of hypoxia sensor--HIF-1α in VEGF gene activation. Implications for angiogenesis and tissue injury healing.Current medicinal chemistry, 19 1
A. Khalyfa, I. Almendros, Alex Gileles-Hillel, Mahzad Akbarpour, W. Trzepizur, B. Mokhlesi, Lei Huang, J. Andrade, R. Farré, D. Gozal (2016)
Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentationOncotarget, 7
A. Federico, F. Morgillo, C. Tuccillo, F. Ciardiello, C. Loguercio (2007)
Chronic inflammation and oxidative stress in human carcinogenesisInternational Journal of Cancer, 121
(2014)
Sleep apnea awakens cancer: a unifying immunological hypothesis
I. Almendros, Yang Wang, L. Becker, Frances Lennon, Jiamao Zheng, Brittney Coats, Kelly Schoenfelt, A. Carreras, F. Hakim, Shelley Zhang, R. Farré, D. Gozal (2014)
Intermittent hypoxia-induced changes in tumor-associated macrophages and tumor malignancy in a mouse model of sleep apnea.American journal of respiratory and critical care medicine, 189 5
M. Martínez-García, F. Campos-Rodriguez, I. Almendros, R. Farré (2015)
Relationship Between Sleep Apnea and Cancer.Archivos de bronconeumologia, 51 9
I. Moreno-Indias, M. Torres, L. Sánchez-Alcoholado, F. Cardona, I. Almendros, D. Gozal, J. Montserrat, M. Queipo-Ortuño, R. Farré (2016)
Normoxic Recovery Mimicking Treatment of Sleep Apnea Does Not Reverse Intermittent Hypoxia-Induced Bacterial Dysbiosis and Low-Grade Endotoxemia in Mice.Sleep, 39 10
Jussara Maragno-Correa, C. Patti, K. Zanin, R. Wuo-Silva, F. Ruiz, A. Zager, A. Sá-Nunes, S. Tufik, M. Andersen, R. Frussa‐Filho (2013)
Sleep Deprivation Increases Mortality in Female Mice Bearing Ehrlich Ascitic TumorNeuroimmunomodulation, 20
B. Lorenzo, Laís Marchioro, C. Greco, D. Suchecki (2015)
Sleep-deprivation reduces NK cell number and function mediated by β-adrenergic signallingPsychoneuroendocrinology, 57
Mahzad Akbarpour, A. Khalyfa, Z. Qiao, Alex Gileles-Hillel, I. Almendros, R. Farré, D. Gozal (2017)
Altered CD8+ T‐Cell Lymphocyte Function and TC1 Cell Stemness Contribute to Enhanced Malignant Tumor Properties in Murine Models of Sleep ApneaSleep, 40
R. Owens, K. Gold, D. Gozal, P. Peppard, J. Jun, A. Dannenberg, S. Lippman, A. Malhotra (2016)
Sleep and Breathing … and Cancer?Cancer Prevention Research, 9
I. Almendros, Yang Wang, D. Gozal (2014)
The polymorphic and contradictory aspects of intermittent hypoxia.American journal of physiology. Lung cellular and molecular physiology, 307 2
M. Coelho, Cátia Soares-Silva, D. Brandão, F. Marino, M. Cosentino, L. Ribeiro (2017)
β-Adrenergic modulation of cancer cell proliferation: available evidence and clinical perspectivesJournal of Cancer Research and Clinical Oncology, 143
W. Childers, Christopher Hollenbeak, P. Cheriyath (2015)
β-Blockers Reduce Breast Cancer Recurrence and Breast Cancer Death: A Meta-Analysis.Clinical breast cancer, 15 6
(2016)
Obstructive Sleep Apnea and Pathological Characteristics of Resected Pancreatic Ductal AdenocarcinomaPLoS ONE, 11
I. Almendros, Alex Gileles-Hillel, A. Khalyfa, Yang Wang, Shelley Zhang, A. Carreras, R. Farré, D. Gozal (2015)
Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: effect of tumor microenvironment.Cancer letters, 361 2
F. Campos-Rodriguez, M. Martínez-García, Montserrat Martínez, J. Durán-Cantolla, M. Peña, M. Masdeu, Mónica González, F. Campo, Inmaculada Gallego, J. Marin, F. Barbé, J. Montserrat, R. Farré (2013)
Association between obstructive sleep apnea and cancer incidence in a large multicenter Spanish cohort.American journal of respiratory and critical care medicine, 187 1
E. Haus, M. Smolensky (2013)
Shift work and cancer risk: potential mechanistic roles of circadian disruption, light at night, and sleep deprivation.Sleep medicine reviews, 17 4
B. Ruffell, Nesrine Affara, L. Coussens (2012)
Differential macrophage programming in the tumor microenvironment.Trends in immunology, 33 3
G. Sethi, M. Shanmugam, Lalitha Ramachandran, A. Kumar, V. Tergaonkar (2012)
Multifaceted link between cancer and inflammation.Bioscience reports, 32 1
T. Papagiannakopoulos, Matthew Bauer, S. Davidson, Megan Heimann, Lakshmi Subbaraj, A. Bhutkar, Jordan Bartlebaugh, M. Heiden, T. Jacks (2016)
Circadian Rhythm Disruption Promotes Lung Tumorigenesis.Cell metabolism, 24 2
G. Semenza (2012)
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.Trends in pharmacological sciences, 33 4
V. Poroyko, A. Carreras, A. Khalyfa, A. Khalyfa, V. Leone, E. Peris, I. Almendros, Alex Gileles-Hillel, Zhuanhong Qiao, Nathaniel Hubert, R. Farré, E. Chang, D. Gozal (2016)
Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in MiceScientific Reports, 6
Dapang Rao, Yu, Yu Bai, Xiangyi Zheng, Liping Xie
Oncotargets and Therapy Dovepress Dovepress Does Night-shift Work Increase the Risk of Prostate Cancer? a Systematic Review and Meta-analysis
R. Colucci, S. Moretti (2016)
The role of stress and beta-adrenergic system in melanoma: current knowledge and possible therapeutic optionsJournal of Cancer Research and Clinical Oncology, 142
D. Golombek, L. Casiraghi, P. Agostino, N. Paladino, José Duhart, S. Plano, J. Chiesa (2013)
The times they’re a-changing: Effects of circadian desynchronization on physiology and diseaseJournal of Physiology-Paris, 107
I. Almendros, A. Khalyfa, W. Trzepizur, Alex Gileles-Hillel, Lei Huang, Mahzad Akbarpour, J. Andrade, R. Farré, D. Gozal (2016)
Tumor Cell Malignant Properties Are Enhanced by Circulating Exosomes in Sleep Apnea.Chest, 150 5
L. Lungato, Amanda Nogueira‐Pedro, Carolina Dias, E. Paredes-Gamero, S. Tufik, V. D’Almeida (2016)
Effects of Sleep Deprivation on Mice Bone Marrow and Spleen B LymphopoiesisJournal of Cellular Physiology, 231
M. Magnone, Sonja Langmesser, A. Bezdek, T. Tallone, S. Rusconi, U. Albrecht (2015)
The Mammalian Circadian Clock Gene Per2 Modulates Cell Death in Response to Oxidative StressFrontiers in Neurology, 5
(2011)
Molecular Pathways: Beta-Adrenergic Signaling in CancerClinical Cancer Research, 18
Jie Cao, Jing Feng, Lian Li, Bao-yuan Chen (2015)
Obstructive sleep apnea promotes cancer development and progression: a concise reviewSleep and Breathing, 19
M. Zielinski, J. Davis, J. Fadel, S. Youngstedt (2012)
Influence of chronic moderate sleep restriction and exercise on inflammation and carcinogenesis in miceBrain, Behavior, and Immunity, 26
D. Gozal, S. Ham, B. Mokhlesi (2016)
SLEEP-DISORDERED BREATHING Sleep Apnea and Cancer : Analysis of a Nationwide Population Sample
S. Hill, T. Frasch, S. Xiang, Lin Yuan, T. Duplessis, L. Mao (2009)
Molecular Mechanisms of Melatonin Anticancer EffectsIntegrative Cancer Therapies, 8
E. Rofstad, Jon-Vidar Gaustad, T. Egeland, B. Mathiesen, Kanthi Galappathi (2010)
Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic disseminationInternational Journal of Cancer, 127
Ruohui He, Yijing He, Yongjun Tang, Honghao Zhou, H. McLeod, Jie Liu (2016)
The potential anticancer effect of beta-blockers and the genetic variations involved in the interindividual difference.Pharmacogenomics, 17 1
D. Gozal, Ramon Farré, Ramon Farré, F. Nieto (2015)
Putative Links Between Sleep Apnea and Cancer: From Hypotheses to Evolving Evidence.Chest, 148 5
V. Ramesh, Deepti Nair, Shelley Zhang, F. Hakim, Navita Kaushal, F. Kayali, Yang Wang, Richard Li, A. Carreras, D. Gozal (2012)
Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathwayJournal of Neuroinflammation, 9
M. Martínez-García, Francisco Campos-Rodríguez, I. Almendros, R. Farré (2015)
Relación entre apnea del sueño y cáncerArchivos De Bronconeumologia, 51
F. Hakim, D. Gozal, L. Kheirandish-Gozal (2012)
Sympathetic and Catecholaminergic Alterations in Sleep Apnea with Particular Emphasis on ChildrenFrontiers in Neurology, 3
D. Gozal, Alex Gileles-Hillel, R. Cortese, Yan Li, I. Almendros, Zhuanhong Qiao, A. Khalyfa, J. Andrade, A. Khalyfa (2017)
Visceral White Adipose Tissue after Chronic Intermittent and Sustained Hypoxia in MiceAmerican Journal of Respiratory Cell and Molecular Biology, 56
I. Almendros, J. Montserrat, M. Torres, M. Bonsignore, L. Chimenti, D. Navajas, R. Farré (2012)
Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea.Sleep medicine, 13 10
S. Méndez-Ferrer, A. Chow, M. Merad, P. Frenette (2009)
Circadian rhythms influence hematopoietic stem cellsCurrent Opinion in Hematology, 16
F. Hakim, Yang Wang, Shelley Zhang, Jiamao Zheng, E. Yolcu, A. Carreras, A. Khalyfa, H. Shirwan, I. Almendros, D. Gozal (2014)
Fragmented sleep accelerates tumor growth and progression through recruitment of tumor-associated macrophages and TLR4 signaling.Cancer research, 74 5
Samantha Greer, J. Metcalf, Yi Wang, M. Ohh (2012)
The updated biology of hypoxia‐inducible factorThe EMBO Journal, 31
B. Abrams (2007)
Cancer and sleep apnea--the hypoxia connection.Medical hypotheses, 68 1
Xiao Wang, Alin Ji, Yi Zhu, Zhen Liang, Jian Wu, Shi-qi Li, Shuai Meng, Xiangyi Zheng, Liping Xie (2015)
A meta-analysis including dose-response relationship between night shift work and the risk of colorectal cancerOncotarget, 6
P. Wood, Xiaoming Yang, W. Hrushesky (2009)
Clock Genes and CancerIntegrative Cancer Therapies, 8
Jiamao Zheng, I. Almendros, Yang Wang, Shelley Zhang, A. Carreras, Zhuanhong Qiao, D. Gozal (2015)
Reduced NADPH oxidase type 2 activity mediates sleep fragmentation-induced effects on TC1 tumors in miceOncoImmunology, 4
I. Moreno-Indias, M. Torres, J. Montserrat, L. Sánchez-Alcoholado, F. Cardona, F. Tinahones, D. Gozal, Valery Poroyko, D. Navajas, M. Queipo-Ortuño, R. Farré (2014)
Intermittent hypoxia alters gut microbiota diversity in a mouse model of sleep apnoeaEuropean Respiratory Journal, 45
K. Dycke, W. Rodenburg, C. Oostrom, L. Kerkhof, J. Pennings, T. Roenneberg, H. Steeg, G. Horst (2015)
Chronically Alternating Light Cycles Increase Breast Cancer Risk in MiceCurrent Biology, 25
Asya Rolls, Asya Rolls, W. Pang, I. Ibarra, D. Colas, P. Bonnavion, B. Korin, Craig Heller, I. Weissman, Luis Lecea (2015)
Sleep disruption impairs hematopoietic stem cell transplantation in miceNature communications, 6
I. Almendros, J. Montserrat, M. Torres, M. Dalmases, M. Cabañas, F. Campos-Rodriguez, D. Navajas, R. Farré (2013)
Intermittent hypoxia increases melanoma metastasis to the lung in a mouse model of sleep apneaRespiratory Physiology & Neurobiology, 186
N. Marshall, Keith Wong, Stewart Cullen, M. Knuiman, R. Grunstein (2014)
Sleep apnea and 20-year follow-up for all-cause mortality, stroke, and cancer incidence and mortality in the Busselton Health Study cohort.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 10 4
Sleep-disordered breathing (SDB) has been linked to wide range of adverse physiologic and pathologic features, from cognitive impairments to increased risk of cancer. In this current review, we will discuss some of the emerging evidence connecting sleep disruption with cancer, by exploring different models of sleep disorders and how they appear to affect cancer. Then, we will summarize our current understanding of the underlying mechanisms, and finally, we will discuss the impact of sleep on one of the frequent and advanced cancer therapies, namely bone marrow transplantation (BMT). Experiments in animal models provide supportive findings, whereby each of the major components of SDB has begun to unravel their potential and complex effects on cancer biology, most likely via alterations in oxidative stress, angiogenesis, immune function, and sympathetic outflow. Future research is undoubtedly needed to better understand the pathophysiologic mechanisms of SDB-related effects on cancer in general, and more specifically on cancer prevention, treatment (chemotherapy, radiation, BMT), and outcomes.
Current Sleep Medicine Reports – Springer Journals
Published: Apr 27, 2017
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.