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Franco Rongioletti, Luigi Corbella, Alfredo Rebora (1988)
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C. Kennedy, C. Bajdik, R. Willemze, F. Gruijl, J. Bavinck (2003)
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C. Lim (2006)
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CJ Cockerell, F Larsen (2003)
Dermatology
Seborrheic keratosis is a benign epidermal tumor but may transform to malignant lesion in sun-exposed areas of the skin. In current study, we report here a patient who presented with multiple cutaneous horns originating from seborrheic keratosis with Bowenoid transformation on the back of the shoulder as an uncommon site. An 88-year-old Iranian woman presented with a multi-conical keratotic projection lesion (7 × 8 cm) on the back of the left shoulder. A biopsy of the lesion revealed intra-epidermal neoplasm that is composed of acanthosis, hyperkeratosis, and parakeratosis. Total thickness of epidermis is composed of atypical squamous cells with foci of individual keratinization, anaplastic cells, and frequent mitosis. Based on the clinical and pathologic findings, we diagnosed this lesion as a cutaneous horn originating from seborrheic keratosis with Bowenoid transformation. Histopathologic examination of all seborrheic keratosis cases should be considered, especially when seborrheic keratosis has atypical clinical manifestations.
Comparative Clinical Pathology – Springer Journals
Published: Mar 4, 2015
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