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Radiologic and Pathologic Correlation of Invasive Lobular Carcinoma of the Breast

Radiologic and Pathologic Correlation of Invasive Lobular Carcinoma of the Breast Purpose of ReviewThe primary goal of this review is to give an update on the radiologic and pathologic features of invasive lobular carcinoma (ILC), with an emphasis on recent studies related to the diagnosis of ILC. We review the imaging features of ILC and also discuss recommendations for avoiding potential pitfalls that can result in a delayed diagnosis. The histologic features of ILC and the role of multidisciplinary radiographic-pathologic correlation in aiding a timely diagnosis of ILC are also discussed.Recent FindingsThere have been recent technologic advancements in breast imaging, including digital breast tomosynthesis, molecular breast imaging, and contrast-enhanced digital mammography, all of which have been shown to outperform conventional digital mammography in the diagnosis of ILC.SummaryThe imaging features of ILC can be subtle due to its lack of significant desmoplastic response, thus making it challenging to diagnose. This underscores the importance of careful radiologic-pathologic correlation and appropriate management of suspicious imaging findings and suspicious clinical findings even in the absence of a correlating imaging abnormality. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Breast Cancer Reports Springer Journals

Radiologic and Pathologic Correlation of Invasive Lobular Carcinoma of the Breast

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References (33)

Publisher
Springer Journals
Copyright
Copyright © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021
ISSN
1943-4588
eISSN
1943-4596
DOI
10.1007/s12609-021-00434-y
Publisher site
See Article on Publisher Site

Abstract

Purpose of ReviewThe primary goal of this review is to give an update on the radiologic and pathologic features of invasive lobular carcinoma (ILC), with an emphasis on recent studies related to the diagnosis of ILC. We review the imaging features of ILC and also discuss recommendations for avoiding potential pitfalls that can result in a delayed diagnosis. The histologic features of ILC and the role of multidisciplinary radiographic-pathologic correlation in aiding a timely diagnosis of ILC are also discussed.Recent FindingsThere have been recent technologic advancements in breast imaging, including digital breast tomosynthesis, molecular breast imaging, and contrast-enhanced digital mammography, all of which have been shown to outperform conventional digital mammography in the diagnosis of ILC.SummaryThe imaging features of ILC can be subtle due to its lack of significant desmoplastic response, thus making it challenging to diagnose. This underscores the importance of careful radiologic-pathologic correlation and appropriate management of suspicious imaging findings and suspicious clinical findings even in the absence of a correlating imaging abnormality.

Journal

Current Breast Cancer ReportsSpringer Journals

Published: Dec 1, 2021

Keywords: Invasive lobular carcinoma; Lobular carcinoma in situ; Radiographic-pathologic correlation

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