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Radiation-Induced Arterial Disease of the Lower Limb Christophe Saliou, MD, Pierre Julia, MD, Boris Feito, MD, Jean-Marc Renaudin, MD, and Jean-Noel Fabiani, MD, Paris, France We describe a case of radiation injury to the superficial femoral and upper popliteal arteries in a 39-year-old man treated 13 years earlier for an osteosarcoma of the right femur. Following two failed attempts at transluminal angioplasty, a saphenous vein femoropopliteal bypass graft was performed successfully. A comprehensive review of the literature on radiation-induced arterial injury to the limbs is presented with a discussion of the different management options. Percu- taneous transluminal balloon angioplasty seems to have no place in the treatment of such lesions (Ann Vasc Surg 1997;11:173-177). chemotherapy (each of Oncovin 2 mg and Methotrexate Therapeutic irradiation can generate arterial lesions 12 g) over a period of 12 months. A total of 48 Grays were that are often asymptomatic. They are occasionally 2 3 4,5 administered to the right lower limb, with another 72 revealed by stenosis, thrombosis, rupture, and, 5,6 Grays of Cobalt therapy to the lesion itself during 6 infrequently, aneurysmal dilatation. These com- weeks. Follow-up was assessed by clinical surveillance, plications arise several years after radiation expo- roentgenogram and
Annals of Vascular Surgery – Springer Journals
Published: Mar 1, 1997
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