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Supplement 1/13 Proceedings of the Annual Meeting of the Austrian Society of Haematology and Oncology Frühjahrstagung 2013 der Österreichischen Gesellschaft für Hämatologie und Onkologie und der Arbeitsgemeinschaft hämato-onkologischer Pflegepersonen in Österreich (AHOP) Linz, 18.–20. April 2013 President : Univ.-Prof. Dr. Peter Bettelheim Secretary: OA Univ.-Doz. Dr. Karl J. Aichberger 1. Interne Abteilung Krankenhaus der Elisabethinen Linz, Austria memo · Vol. 6 · Suppl 1/13 © Springer-Verlag Wien 1 Published online: 3 April 2013 Supplement 1/13 2 Suppl 1/13 1 3 Abstracts Background: The combination of chemotherapy and anti-EGFR Young Investigators Oral monoclonal antibodies has proven clinical efficacy in NSCLC. Recent reports emphasize the important role of increased Treg lev- Presentations els for tumor immune escape in epithelial malignancies. The aim of the current study is to determine the role of Treg levels for thera- peutic response and the impact of neoadjuvant chemo-immuno- A01 therapy on the Treg compartment. Methods: We first analyzed in-vitro the effects of Treg on natu- ral killer cell-mediated cetuximab-antibody dependent cellular The impact of miR-155 on cytokine cytoxicity. 31 patients suffering from NSCLC were included in a regulation and tumor growth in neoadjuvant study protocol and received two cycles of chemo- immunotherapy (Cetuximab+Docetaxel+Cisplatin) prior to
memo - Magazine of European Medical Oncology – Springer Journals
Published: Apr 3, 2013
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