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Primary Basal Cell Carcinoma

Primary Basal Cell Carcinoma A large number of management options are available for treating basal cell carcinoma (BCC). While surgical resection is the gold standard treatment, novel approaches are constantly being developed and studied to treat tumors effectively and safely in a noninvasive way. A decade ago, several modalities such as immunotherapy and photodynamic therapy were considered investigational. Today, such drugs as imiquimod and porfimer sodium (Photofrin™) are being reported in the literature for treatment of selected BCCs. Some efforts have focused on increasing drug delivery or penetration into tumors with electrochemotherapy and cytotoxic agents. Other advances in drug therapy, such as chemoprevention with retinoids appear promising but may need further trials to gain acceptance. This review explores the potential of drug therapy for BCCs. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Cancer Springer Journals

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Publisher
Springer Journals
Copyright
Copyright © 2004 by Adis Data Information BV
Subject
Pharmacy; Pharmacy
ISSN
1175-6357
DOI
10.2165/00024669-200403030-00004
Publisher site
See Article on Publisher Site

Abstract

A large number of management options are available for treating basal cell carcinoma (BCC). While surgical resection is the gold standard treatment, novel approaches are constantly being developed and studied to treat tumors effectively and safely in a noninvasive way. A decade ago, several modalities such as immunotherapy and photodynamic therapy were considered investigational. Today, such drugs as imiquimod and porfimer sodium (Photofrin™) are being reported in the literature for treatment of selected BCCs. Some efforts have focused on increasing drug delivery or penetration into tumors with electrochemotherapy and cytotoxic agents. Other advances in drug therapy, such as chemoprevention with retinoids appear promising but may need further trials to gain acceptance. This review explores the potential of drug therapy for BCCs.

Journal

American Journal of CancerSpringer Journals

Published: Aug 10, 2012

References