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Preparation, characterization and bioactivity assessment of chitosan-acetylated jute blended green films

Preparation, characterization and bioactivity assessment of chitosan-acetylated jute blended... Abstract In recent years, there has been a great demand for artificial materials for biomedical applications, especially to bone growth. In the present study, the in vitro bioactivity of chitosan-acetylated jute blended film was investigated through biomimitic growth of bone-like apatite layer formation in simulated body fluid (SBF) on the surface of the film. Chitosan was prepared from crab shells and the blended film was prepared by solvent casting method using 10 % formic acid aqueous solution of in-house chitosan and mercerized, acetylated jute fiber. Water absorption characteristics (swelling test) and tensile strength (Universal testing machine) of the films were determined. Thermal behavior of the films were examined by TGA analysis. The biocompatibility of the chitosan-acetylated jute (CAJ) film was indicated by the formation of hydroxy apatite (HAp) bone-like layer formed on the surface when soaked in SBF solution for 14 days. The topography of the film was characterized by scanning electron microscope (SEM) and Ca/P ratio of the apatite layer was confirmed to be 50:50 by EDX analysis. The results showed that the CAJ film will be a promising bone substituting material. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Fibers and Polymers Springer Journals

Preparation, characterization and bioactivity assessment of chitosan-acetylated jute blended green films

Fibers and Polymers , Volume 14 (9): 6 – Sep 1, 2013

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References (17)

Publisher
Springer Journals
Copyright
2013 The Korean Fiber Society and Springer Science+Business Media Dordrecht
ISSN
1229-9197
eISSN
1875-0052
DOI
10.1007/s12221-013-1454-z
Publisher site
See Article on Publisher Site

Abstract

Abstract In recent years, there has been a great demand for artificial materials for biomedical applications, especially to bone growth. In the present study, the in vitro bioactivity of chitosan-acetylated jute blended film was investigated through biomimitic growth of bone-like apatite layer formation in simulated body fluid (SBF) on the surface of the film. Chitosan was prepared from crab shells and the blended film was prepared by solvent casting method using 10 % formic acid aqueous solution of in-house chitosan and mercerized, acetylated jute fiber. Water absorption characteristics (swelling test) and tensile strength (Universal testing machine) of the films were determined. Thermal behavior of the films were examined by TGA analysis. The biocompatibility of the chitosan-acetylated jute (CAJ) film was indicated by the formation of hydroxy apatite (HAp) bone-like layer formed on the surface when soaked in SBF solution for 14 days. The topography of the film was characterized by scanning electron microscope (SEM) and Ca/P ratio of the apatite layer was confirmed to be 50:50 by EDX analysis. The results showed that the CAJ film will be a promising bone substituting material.

Journal

Fibers and PolymersSpringer Journals

Published: Sep 1, 2013

Keywords: Polymer Sciences

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