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Poster 1007: Universal allergen particle generation for inhaled allergen challenges in the fraunhofer environmental challenge chamber (ECC)

Poster 1007: Universal allergen particle generation for inhaled allergen challenges in the... Hohlfeld et al. World Allergy Organization Journal 2014, 7(Suppl 1):P4 http://www.waojournal.org/content/7/S1/P4 POSTER PRESENTATION Open Access Poster 1007: Universal allergen particle generation for inhaled allergen challenges in the fraunhofer environmental challenge chamber (ECC) 1* 1 1 1 1 1 1 Jens M Hohlfeld , Katrin Lueer , Heike Biller , Horst Windt , Philipp Badorrek , Meike Mueller , Holger Ziehr , 2 1 1 Dietrich Haefner , Norbert Krug , Wolfgang Koch From 2013 WAO Symposium on Immunotherapy and Biologics Chicago, IL, USA. 13-14 December 2013 Background Results Efficacy testing of immunotherapy in field studies is often Allergen exposure was safe and significantly elicited hampered by variation of airborne allergens. Standardized symptoms of AR compared to room air exposure with a allergen exposure in challenge chamber settings might mean total nasal symptom score (TNSS) of 3.6±2.0 overcome aforementioned limitations. However, airborne (mean±SD) at the highest allergen concentration. Lactose allergens such as house dust mite (HDM) or cat allergen alone did not change TNSS (0.7±0.6) compared to pre- are not available as standardized source material with dis- challenge level. Repeated exposure to 500 SQE/m tinct particle size. Therefore, we developed a method for induced a TNSS which was notdifferent betweenthe http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png World Allergy Organization Journal Springer Journals

Poster 1007: Universal allergen particle generation for inhaled allergen challenges in the fraunhofer environmental challenge chamber (ECC)

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Poster 1007: Universal allergen particle generation for inhaled allergen challenges in the fraunhofer environmental challenge chamber (ECC)

Abstract

Hohlfeld et al. World Allergy Organization Journal 2014, 7(Suppl 1):P4 http://www.waojournal.org/content/7/S1/P4 POSTER PRESENTATION Open Access Poster 1007: Universal allergen particle generation for inhaled allergen challenges in the fraunhofer environmental challenge chamber (ECC) 1* 1 1 1 1 1 1 Jens M Hohlfeld , Katrin Lueer , Heike Biller , Horst Windt , Philipp Badorrek , Meike Mueller , Holger Ziehr , 2 1 1 Dietrich Haefner , Norbert Krug , Wolfgang Koch From 2013 WAO Symposium on...
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Publisher
Springer Journals
Copyright
Copyright © 2014 by Hohlfeld et al; licensee BioMed Central Ltd.
Subject
Medicine & Public Health; Allergology; Immunology
eISSN
1939-4551
DOI
10.1186/1939-4551-7-S1-P4
Publisher site
See Article on Publisher Site

Abstract

Hohlfeld et al. World Allergy Organization Journal 2014, 7(Suppl 1):P4 http://www.waojournal.org/content/7/S1/P4 POSTER PRESENTATION Open Access Poster 1007: Universal allergen particle generation for inhaled allergen challenges in the fraunhofer environmental challenge chamber (ECC) 1* 1 1 1 1 1 1 Jens M Hohlfeld , Katrin Lueer , Heike Biller , Horst Windt , Philipp Badorrek , Meike Mueller , Holger Ziehr , 2 1 1 Dietrich Haefner , Norbert Krug , Wolfgang Koch From 2013 WAO Symposium on Immunotherapy and Biologics Chicago, IL, USA. 13-14 December 2013 Background Results Efficacy testing of immunotherapy in field studies is often Allergen exposure was safe and significantly elicited hampered by variation of airborne allergens. Standardized symptoms of AR compared to room air exposure with a allergen exposure in challenge chamber settings might mean total nasal symptom score (TNSS) of 3.6±2.0 overcome aforementioned limitations. However, airborne (mean±SD) at the highest allergen concentration. Lactose allergens such as house dust mite (HDM) or cat allergen alone did not change TNSS (0.7±0.6) compared to pre- are not available as standardized source material with dis- challenge level. Repeated exposure to 500 SQE/m tinct particle size. Therefore, we developed a method for induced a TNSS which was notdifferent betweenthe

Journal

World Allergy Organization Journal – Springer Journals

Published: Feb 3, 2014

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