Access the full text.
Sign up today, get DeepDyve free for 14 days.
(2015)
Diagnostic efficacy of 68gallium-PSMA- PET compared to conventional imaging in lymph node staging of of 130 consecutive patients with intermediate to high-risk prostate cancer
A. Afshar-Oromieh, Eleni Avtzi, F. Giesel, T. Holland-Letz, H. Linhart, M. Eder, M. Eisenhut, S. Boxler, B. Hadaschik, C. Kratochwil, W. Weichert, K. Kopka, J. Debus, U. Haberkorn (2014)
The diagnostic value of PET/CT imaging with the 68Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancerEuropean Journal of Nuclear Medicine and Molecular Imaging, 42
M. Eiber, G. Weirich, K. Holzapfel, M. Souvatzoglou, B. Haller, I. Rauscher, A. Beer, H. Wester, J. Gschwend, M. Schwaiger, T. Maurer (2016)
Simultaneous 68Ga-PSMA HBED-CC PET/MRI Improves the Localization of Primary Prostate Cancer.European urology, 70 5
A. Ghosh, W. Heston (2004)
Tumor target prostate specific membrane antigen (PSMA) and its regulation in prostate cancerJournal of Cellular Biochemistry, 91
F. Sterzing, C. Kratochwil, H. Fiedler, S. Katayama, G. Habl, K. Kopka, A. Afshar-Oromieh, J. Debus, U. Haberkorn, F. Giesel (2015)
68Ga-PSMA-11 PET/CT: a new technique with high potential for the radiotherapeutic management of prostate cancer patientsEuropean Journal of Nuclear Medicine and Molecular Imaging, 43
Maudy Gayet, Anouk Aa, H. Beerlage, B. Schrier, P. Mulders, H. Wijkstra (2016)
The value of magnetic resonance imaging and ultrasonography (MRI/US)-fusion biopsy platforms in prostate cancer detection
A. Afshar-Oromieh, C. Zechmann, A. Malcher, M. Eder, M. Eisenhut, H. Linhart, T. Holland-Letz, B. Hadaschik, F. Giesel, J. Debus, U. Haberkorn (2013)
Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancerEuropean Journal of Nuclear Medicine and Molecular Imaging, 41
M. Beresford, D. Gillatt, Richard Benson, T. Ajithkumar (2010)
A systematic review of the role of imaging before salvage radiotherapy for post-prostatectomy biochemical recurrence.Clinical oncology (Royal College of Radiologists (Great Britain)), 22 1
B. Krause, M. Souvatzoglou, M. Tuncel, K. Herrmann, A. Buck, C. Praus, T. Schuster, H. Geinitz, U. Treiber, M. Schwaiger (2007)
The detection rate of [11C]Choline-PET/CT depends on the serum PSA-value in patients with biochemical recurrence of prostate cancerEuropean Journal of Nuclear Medicine and Molecular Imaging, 35
L. Kabasakal, Mohammad Abuqbeitah, Aslan Aygün, Nami Yeyin, M. Ocak, E. Demirci, Türkay Toklu (2015)
Pre-therapeutic dosimetry of normal organs and tissues of 177Lu-PSMA-617 prostate-specific membrane antigen (PSMA) inhibitor in patients with castration-resistant prostate cancerEuropean Journal of Nuclear Medicine and Molecular Imaging, 42
H. Jadvar (2012)
Molecular imaging of prostate cancer: PET radiotracers.AJR. American journal of roentgenology, 199 2
R. Siegel, K. Miller, A. Jemal (2015)
Cancer statistics, 2015CA: A Cancer Journal for Clinicians, 65
R. Baum, H. Kulkarni, C. Schuchardt, Aviral Singh, M. Wirtz, S. Wiessalla, M. Schottelius, D. Mueller, I. Klette, H. Wester (2016)
177Lu-Labeled Prostate-Specific Membrane Antigen Radioligand Therapy of Metastatic Castration-Resistant Prostate Cancer: Safety and EfficacyThe Journal of Nuclear Medicine, 57
Magne Dimmen, L. Vlatkovic, K. Hole, J. Nesland, B. Brennhovd, K. Axcrona (2012)
Transperineal prostate biopsy detects significant cancer in patients with elevated prostate‐specific antigen (PSA) levels and previous negative transrectal biopsiesBJU International, 110
T. Maurer, J. Gschwend, I. Rauscher, M. Souvatzoglou, B. Haller, G. Weirich, H. Wester, M. Heck, H. Kübler, A. Beer, M. Schwaiger, M. Eiber (2016)
Diagnostic Efficacy of (68)Gallium-PSMA Positron Emission Tomography Compared to Conventional Imaging for Lymph Node Staging of 130 Consecutive Patients with Intermediate to High Risk Prostate Cancer.The Journal of urology, 195 5
T. Krohn, F. Verburg, T. Pufe, W. Neuhuber, A. Vogg, A. Heinzel, F. Mottaghy, F. Behrendt (2015)
[68Ga]PSMA-HBED uptake mimicking lymph node metastasis in coeliac ganglia: an important pitfall in clinical practiceEuropean Journal of Nuclear Medicine and Molecular Imaging, 42
M. Valentinuzzi (2010)
SAFETY AND EFFICACY
S. Perner, M. Hofer, R. Kim, R. Shah, Haojie Li, P. Möller, R. Hautmann, J. Gschwend, R. Kuefer, M. Rubin (2007)
Prostate-specific membrane antigen expression as a predictor of prostate cancer progression.Human pathology, 38 5
(2015)
Evaluation of hybrid 68 Ga-PSMA ligand PET/CT in 248 patients with biochemical recurrence after radical prostatectomy
L. Schimmöller, M. Quentin, C. Arsov, A. Hiester, C. Buchbender, R. Rabenalt, P. Albers, G. Antoch, D. Blondin (2014)
MR-sequences for prostate cancer diagnostics: validation based on the PI-RADS scoring system and targeted MR-guided in-bore biopsyEuropean Radiology, 24
D. Pfister, M. Bolla, A. Briganti, P. Carroll, C. Cozzarini, S. Joniau, H. Poppel, M. Roach, A. Stephenson, T. Wiegel, M. Zelefsky
Platinum Priority – Collaborative Review – Prostate Cancer Early Salvage Radiotherapy following Radical Prostatectomy
M. Eiber, T. Maurer, M. Souvatzoglou, A. Beer, A. Ruffani, B. Haller, F. Graner, H. Kübler, Uwe Haberhorn, M. Eisenhut, H. Wester, J. Gschwend, M. Schwaiger (2015)
Evaluation of Hybrid 68Ga-PSMA Ligand PET/CT in 248 Patients with Biochemical Recurrence After Radical ProstatectomyThe Journal of Nuclear Medicine, 56
F. Ceci, C. Uprimny, B. Nilica, L. Geraldo, D. Kendler, A. Kroiss, J. Bektic, W. Horninger, P. Lukas, C. Decristoforo, P. Castellucci, S. Fanti, I. Virgolini (2015)
68Ga-PSMA PET/CT for restaging recurrent prostate cancer: which factors are associated with PET/CT detection rate?European Journal of Nuclear Medicine and Molecular Imaging, 42
W. Wang, F. Távora, Rajni Sharma, M. Eisenberger, G. Netto (2009)
PSMA expression in Schwannoma: a potential clinical mimicker of metastatic prostate carcinoma.Urologic oncology, 27 5
Sam Chang, D. O’Keefe, D. Bacich, Victor Reuter, Warren Heston, P. Gaudin (1999)
Prostate-specific membrane antigen is produced in tumor-associated neovasculature.Clinical cancer research : an official journal of the American Association for Cancer Research, 5 10
A. Afshar-Oromieh, A. Malcher, M. Eder, M. Eisenhut, H. Linhart, B. Hadaschik, T. Holland-Letz, F. Giesel, C. Kratochwil, S. Haufe, U. Haberkorn, C. Zechmann (2013)
Reply to Reske et al.: PET imaging with a [68Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesionsEuropean Journal of Nuclear Medicine and Molecular Imaging, 40
M. Samplaski, W. Heston, P. Elson, C. Magi-Galluzzi, D. Hansel (2011)
Folate hydrolase (prostate-specific antigen) 1 expression in bladder cancer subtypes and associated tumor neovasculatureModern Pathology, 24
David Silver, Inmaculada Pellicer, W. Fair, W. Heston, C. Cordon-Cardo (1997)
Prostate-specific membrane antigen expression in normal and malignant human tissues.Clinical cancer research : an official journal of the American Association for Cancer Research, 3 1
The detection of lesions in the context of biochemical recurrence of prostate cancer is a major challenge for all imaging modalities. Recently, the prostate-specific membrane antigen (PSMA) is recognized as a novel target for the PET–CT (positron emission tomography–computed tomography) imaging of prostate cancer with the tracer 68Ga-PSMA (68Gallium-labelled PSMA), mainly in the detection of relapses and metastasis. PSMA PET–CT imaging shows high tracer uptake at the sites of primary tumor and lymph node, and bone metastasis in direct correlation with aggressiveness and Gleason scores. PSMA PET–CT seems to be a highly accurate imaging tool for restaging of prostate cancer patients with biochemical recurrence, and it proved to be clearly superior in detecting prostate cancer lesions at low PSA levels when compared to other methods.
Current Radiology Reports – Springer Journals
Published: Oct 28, 2016
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.