Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

P31 - Natural history of wheat allergy in Greek children

P31 - Natural history of wheat allergy in Greek children Giavi et al. Clinical and Translational Allergy 2014, 4(Suppl 1):P86 http://www.ctajournal.com/content/4/S1/P86 POSTER PRESENTATION Open Access P31 - Natural history of wheat allergy in Greek children Stavroula Giavi, Paraskevi Korovessi , Nikolaos Douladiris, Emmanouil Manousakis, Nikolaos G Papadopoulos From 3rd Pediatric Allergy and Asthma Meeting (PAAM) Athens, Greece. 17-19 October 2013 Background population and 75% of them had no history of other food Wheat allergy is one of the most common food allergies in allergy. In contrast, all children with resolved wheat allergy children, yet few data are available regarding its natural had multiple food allergies. history. Conclusion Objectives The mean age of resolution of wheat allergy is approxi- To define the natural course of wheat allergy in Greek mately 11 years in this population (95% CI : 9,6-12,3). In a children and identify factors that may predict outcome. significant percentage of patients, wheat allergy persists into adolescence. Many children outgrew wheat allergy Methods with even the highest levels of specific wheat IgE. We completed a retrospective medical record review of Monosensitization to wheat appears to be a risk factor for patients from the Allergy Clinic, 2nd Pediatric Clinic, persistence. University of Athens that were diagnosed as having wheat allergy. Patients were included in the study if they Published: 28 February 2014 had a history of symptomatic reaction to wheat and or a positive wheat IgE test result. Clinical history, laboratory results, and final outcome doi:10.1186/2045-7022-4-S1-P86 were recorded for 70 patients. Resolution of wheat allergy Cite this article as: Giavi et al.: P31 - Natural history of wheat allergy in was based on food challenge results. Total IgE, wheat Greek children. Clinical and Translational Allergy 2014 4(Suppl 1):P86. IgE (f4), specific gluten IgE (f79) and the ratio f4/ lgE, (at presentation), were compared between children with active or resolved wheat allergy, 4 years after their first reaction, performing the non-parametric Mann-Whitney test. Results Submit your next manuscript to BioMed Central Rates of resolution were 20% by 5 years, 35% by 10 years and take full advantage of: (determined by Kaplan-Meier survival curves). Higher total IgE, f4, f79 or f4/IgE levels (at presentation) were • Convenient online submission not strongly associated with poorer outcomes at 4 years. • Thorough peer review f79 (p = 0.095) and f4 (p = 0.063) slightly correlated with • No space constraints or color figure charges active allergy. • Immediate publication on acceptance Median age of first reaction to wheat was 8 months. • Inclusion in PubMed, CAS, Scopus and Google Scholar History of AD was present at 96% of all children. Children • Research which is freely available for redistribution with still active wheat allergy accounted for the 72% of the Submit your manuscript at www.biomedcentral.com/submit nd Allergy Clinic, 2 Pediatric Clinic, University of Athens, Athens, Greece © 2014 Giavi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical and Translational Allergy Springer Journals

P31 - Natural history of wheat allergy in Greek children

Download PDF
1 page

Loading next page...
 
/lp/springer-journals/p31-natural-history-of-wheat-allergy-in-greek-children-6J18djTc0z

References (0)

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Springer Journals
Copyright
Copyright © 2014 by Giavi et al; licensee BioMed Central Ltd.
Subject
Medicine & Public Health; Allergology; Immunology
eISSN
2045-7022
DOI
10.1186/2045-7022-4-S1-P86
Publisher site
See Article on Publisher Site

Abstract

Giavi et al. Clinical and Translational Allergy 2014, 4(Suppl 1):P86 http://www.ctajournal.com/content/4/S1/P86 POSTER PRESENTATION Open Access P31 - Natural history of wheat allergy in Greek children Stavroula Giavi, Paraskevi Korovessi , Nikolaos Douladiris, Emmanouil Manousakis, Nikolaos G Papadopoulos From 3rd Pediatric Allergy and Asthma Meeting (PAAM) Athens, Greece. 17-19 October 2013 Background population and 75% of them had no history of other food Wheat allergy is one of the most common food allergies in allergy. In contrast, all children with resolved wheat allergy children, yet few data are available regarding its natural had multiple food allergies. history. Conclusion Objectives The mean age of resolution of wheat allergy is approxi- To define the natural course of wheat allergy in Greek mately 11 years in this population (95% CI : 9,6-12,3). In a children and identify factors that may predict outcome. significant percentage of patients, wheat allergy persists into adolescence. Many children outgrew wheat allergy Methods with even the highest levels of specific wheat IgE. We completed a retrospective medical record review of Monosensitization to wheat appears to be a risk factor for patients from the Allergy Clinic, 2nd Pediatric Clinic, persistence. University of Athens that were diagnosed as having wheat allergy. Patients were included in the study if they Published: 28 February 2014 had a history of symptomatic reaction to wheat and or a positive wheat IgE test result. Clinical history, laboratory results, and final outcome doi:10.1186/2045-7022-4-S1-P86 were recorded for 70 patients. Resolution of wheat allergy Cite this article as: Giavi et al.: P31 - Natural history of wheat allergy in was based on food challenge results. Total IgE, wheat Greek children. Clinical and Translational Allergy 2014 4(Suppl 1):P86. IgE (f4), specific gluten IgE (f79) and the ratio f4/ lgE, (at presentation), were compared between children with active or resolved wheat allergy, 4 years after their first reaction, performing the non-parametric Mann-Whitney test. Results Submit your next manuscript to BioMed Central Rates of resolution were 20% by 5 years, 35% by 10 years and take full advantage of: (determined by Kaplan-Meier survival curves). Higher total IgE, f4, f79 or f4/IgE levels (at presentation) were • Convenient online submission not strongly associated with poorer outcomes at 4 years. • Thorough peer review f79 (p = 0.095) and f4 (p = 0.063) slightly correlated with • No space constraints or color figure charges active allergy. • Immediate publication on acceptance Median age of first reaction to wheat was 8 months. • Inclusion in PubMed, CAS, Scopus and Google Scholar History of AD was present at 96% of all children. Children • Research which is freely available for redistribution with still active wheat allergy accounted for the 72% of the Submit your manuscript at www.biomedcentral.com/submit nd Allergy Clinic, 2 Pediatric Clinic, University of Athens, Athens, Greece © 2014 Giavi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Journal

Clinical and Translational Allergy – Springer Journals

Published: Feb 28, 2014

There are no references for this article.