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On the possibility of using multi-element phased arrays for shock-wave action on deep brain structures

On the possibility of using multi-element phased arrays for shock-wave action on deep brain... Abstract A noninvasive ultrasound surgery method that relies on using multi-element focused phased arrays is being successfully used to destroy tumors and perform neurosurgical operations in deep structures of the human brain. However, several drawbacks that limit the possibilities of the existing systems in their clinical use have been revealed: a large size of the hemispherical array, impossibility of its mechanical movement relative to the patient’s head, limited volume of dynamic focusing around the center of curvature of the array, and side effect of overheating skull. Here we evaluate the possibility of using arrays of smaller size and aperture angles to achieve shock-wave formation at the focus for thermal and mechanical ablation (histotripsy) of brain tissue taking into account current intensity limitations at the array elements. The proposed approach has potential advantages to mitigate the existing limitations and expand the possibilities of transcranial ultrasound surgery. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acoustical Physics Springer Journals

On the possibility of using multi-element phased arrays for shock-wave action on deep brain structures

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References (33)

Publisher
Springer Journals
Copyright
2017 Pleiades Publishing, Ltd.
ISSN
1063-7710
eISSN
1562-6865
DOI
10.1134/S1063771017050104
Publisher site
See Article on Publisher Site

Abstract

Abstract A noninvasive ultrasound surgery method that relies on using multi-element focused phased arrays is being successfully used to destroy tumors and perform neurosurgical operations in deep structures of the human brain. However, several drawbacks that limit the possibilities of the existing systems in their clinical use have been revealed: a large size of the hemispherical array, impossibility of its mechanical movement relative to the patient’s head, limited volume of dynamic focusing around the center of curvature of the array, and side effect of overheating skull. Here we evaluate the possibility of using arrays of smaller size and aperture angles to achieve shock-wave formation at the focus for thermal and mechanical ablation (histotripsy) of brain tissue taking into account current intensity limitations at the array elements. The proposed approach has potential advantages to mitigate the existing limitations and expand the possibilities of transcranial ultrasound surgery.

Journal

Acoustical Physics – Springer Journals

Published: Sep 1, 2017

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