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X. Yi, Huajian Gao (2017)
Kinetics of receptor-mediated endocytosis of elastic nanoparticles.Nanoscale, 9 1
E. Kihlström, L. Nilsson (2009)
Endocytosis of Salmonella typhimurium 395 MS and MR10 by HeLa cells.Acta pathologica et microbiologica Scandinavica. Section B, Microbiology, 85B 5
M. Marsh (2001)
Clathrin-coated Vesicles and Receptor-mediated Endocytosis
Xinyu Tan, J. Heureaux, Allen Liu (2015)
Cell spreading area regulates clathrin-coated pit dynamics on micropatterned substrate.Integrative biology : quantitative biosciences from nano to macro, 7 9
A. Diz-Muñoz, D. Fletcher, O. Weiner (2013)
Use the force: membrane tension as an organizer of cell shape and motility.Trends in cell biology, 23 2
B. Chithrani, A. Ghazani, W. Chan (2006)
Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells.Nano letters, 6 4
S. Dmitrieff, F. Nédélec (2015)
Membrane Mechanics of Endocytosis in Cells with TurgorPLoS Computational Biology, 11
D. Raucher, M. Sheetz (1999)
Membrane Expansion Increases Endocytosis Rate during MitosisThe Journal of Cell Biology, 144
Tetsuro Tanaka, S. Shiramoto, M. Miyashita, Y. Fujishima, Y. Kaneo (2004)
Tumor targeting based on the effect of enhanced permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis (RME).International journal of pharmaceutics, 277 1-2
F. David, S. Leibler (1991)
Vanishing tension of fluctuating membranesJournal De Physique Ii, 1
C. Choi, C. Alabi, P. Webster, Mark Davis (2009)
Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticlesProceedings of the National Academy of Sciences, 107
J. Goldstein, R. Anderson, Michael Brown (1979)
Coated pits, coated vesicles, and receptor-mediated endocytosisNature, 279
Jiashu Sun, Lu Zhang, Jiuling Wang, Qiang Feng, Dingbin Liu, Qifang Yin, Dongyan Xu, Yujie Wei, Baoquan Ding, Xinghua Shi, Xingyu Jiang (2015)
Tunable Rigidity of (Polymeric Core)–(Lipid Shell) Nanoparticles for Regulated Cellular UptakeAdvanced Materials, 27
R. Hochmuth, C. Evans, H. Wiles, J. Mccown (1983)
Mechanical measurement of red cell membrane thickness.Science, 220 4592
(1994)
On peeling an adherent cell from a surface
D. Loerke, Marcel Mettlen, D. Yarar, K. Jaqaman, H. Jaqaman, G. Danuser, S. Schmid (2009)
Cargo and Dynamin Regulate Clathrin-Coated Pit MaturationPLoS Biology, 7
T. Brett, L. Traub (2006)
Molecular structures of coat and coat-associated proteins: function follows form.Current opinion in cell biology, 18 4
Xinyue Liu, Yunqiao Liu, X. Gong, Huaxiong Huang (2018)
A Numerical Study of Passive Receptor-Mediated Endocytosis of Nanoparticles: The Effect of Mechanical PropertiesComputer Modeling in Engineering & Sciences
E. Irajizad, Nikhil Walani, S. Veatch, Allen Liu, A. Agrawal (2017)
Clathrin polymerization exhibits high mechano-geometric sensitivity.Soft matter, 13 7
Jian Liu, M. Kaksonen, D. Drubin, G. Oster (2006)
Endocytic vesicle scission by lipid phase boundary forcesProceedings of the National Academy of Sciences, 103
Vincent Moy, E. Florin, H. Gaub (1994)
Intermolecular forces and energies between ligands and receptors.Science, 266 5183
X. Yi, Xinghua Shi, Huajian Gao (2011)
Cellular uptake of elastic nanoparticles.Physical review letters, 107 9
T. Kirchhausen, D. Owen, S. Harrison (2014)
Molecular structure, function, and dynamics of clathrin-mediated membrane traffic.Cold Spring Harbor perspectives in biology, 6 5
S. Boulant, C. Kural, Jean-Christophe Zeeh, Florent Ubelmann, T. Kirchhausen (2011)
Actin dynamics counteract membrane tension during clathrin-mediated endocytosisNature cell biology, 13
M. Ehrlich, W. Boll, A. Oijen, R. Hariharan, K. Chandran, M. Nibert, T. Kirchhausen (2004)
Endocytosis by Random Initiation and Stabilization of Clathrin-Coated PitsCell, 118
Ori Avinoam, Martin Schorb, C. Beese, J. Briggs, M. Kaksonen (2015)
Endocytic sites mature by continuous bending and remodeling of the clathrin coatScience, 348
A. Jin, K. Prasad, Paul Smith, E. Lafer, R. Nossal (2006)
Measuring the elasticity of clathrin-coated vesicles via atomic force microscopy.Biophysical journal, 90 9
M. Oh, F. Kuhr, F. Byfield, I. Levitan (2012)
Micropipette aspiration of substrate-attached cells to estimate cell stiffness.Journal of visualized experiments : JoVE, 67
(1993)
Principles of Molecular Virology: Trends in Biochemical Sciences
T. Wileman, C. Harding, P. Stahl (1985)
Receptor-mediated endocytosis.The Biochemical journal, 232 1
J. Heuser (1980)
Three-dimensional visualization of coated vesicle formation in fibroblastsThe Journal of Cell Biology, 84
AL Schwartz P Stahl (1986)
Receptor-mediated endocytosisJ. Clin. Invest., 77
S. Schmid (1997)
Clathrin-coated vesicle formation and protein sorting: an integrated process.Annual review of biochemistry, 66
Xin-sheng Wu, Sharon Elias, Huisheng Liu, J. Heureaux, Peter Wen, Allen Liu, M. Kozlov, Ling-Gang Wu (2017)
Membrane Tension Inhibits Rapid and Slow Endocytosis in Secretory Cells.Biophysical journal, 113 11
Stephanie Tortorella, T. Karagiannis (2014)
Transferrin Receptor-Mediated Endocytosis: A Useful Target for Cancer TherapyThe Journal of Membrane Biology, 247
Aubrey Weigel, M. Tamkun, D. Krapf (2013)
Quantifying the dynamic interactions between a clathrin-coated pit and cargo moleculesProceedings of the National Academy of Sciences, 110
Yifan Cheng, O. Zak, P. Aisen, S. Harrison, T. Walz (2004)
Structure of the Human Transferrin Receptor-Transferrin ComplexCell, 116
P. Decuzzi, M. Ferrari (2007)
The role of specific and non-specific interactions in receptor-mediated endocytosis of nanoparticles.Biomaterials, 28 18
(2005)
Mechanics of receptor-mediated endocytosis.Proceedings of the National Academy of Sciences of the United States of America, 102 27
R. Skalak, A. Tozeren, R. Zarda, S. Chien (1973)
Strain energy function of red blood cell membranes.Biophysical journal, 13 3
T. Chou (2007)
Stochastic entry of enveloped viruses: fusion versus endocytosis.Biophysical journal, 93 4
W. Helfrich (1973)
Elastic Properties of Lipid Bilayers: Theory and Possible ExperimentsZeitschrift für Naturforschung C, 28
Abstract In this study, a three-dimensional mathematical model was used to study the contribution of clathrins during the process of cellular uptake of spherical nanoparticles under different membrane tensions. The clathrin-coated pit (CCP) that forms around the inward budding of the cell membrane was modeled as a vesicle with bending rigidity. An optimization algorithm was proposed for minimizing the total energy of the system, which comprises the deforming nanoparticle, receptor–ligand bonds, cell membrane, and CCP, in which way, the profile of the system is acquired. The results showed that the CCP enable full wrapping of the nanoparticles at various membrane tensions. When the cell membrane tension increases, the total deformation energy also increases, but the ratio of CCP bending to the minimum value of the total energy of the system decreases. The results also showed that the diameter of the endocytic vesicles determined by the competition between the stretching of the cell membrane and confinement of the coated pits are much larger than the nanoparticles, which is quit different as the results in passive endocytosis that is not facilitated by the CCPs. The present results indicate that variations of tension on cell membranes constitutes a biophysical marker for understanding the size distribution of CCPs observed in experiments. The present results also suggest that the early abortion of endocytosis is related to that the receptor–ligand bonds cannot generate adequate force to wrap the nanoparticles into the cell membrane before the clathrins respond to support the endocytic vesicles. Correspondingly, late abortion may relate to the inability of CCPs to confine the nanoparticles until the occurrence of the necking stage of endocytosis.
"Acta Mechanica Sinica" – Springer Journals
Published: Jun 1, 2019
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