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Indian J Surg Oncol (December 2013) 4(4):362–365 DOI 10.1007/s13193-013-0255-6 CASE REPORT Nonresponsiveness to Chemotherapy: A Formidable Surgical Challenge in Wilms’ Tumor with Intracardiac Extension Sandesh V. Parelkar & Dinesh Mundada & Sanjay N. Oak & Beejal V. Sanghvi & Prashant B. Joshi & Satish P. Kapadnis & D. K. Kulkarni Received: 25 March 2013 /Accepted: 25 June 2013 /Published online: 11 July 2013 Indian Association of Surgical Oncology 2013 Introduction Per-cutaneous computed tomography (CT) guided tumor biopsy revealed favorable Wilms’ tumor. With stage III dis- Intracaval tumor extension is reported in 4 % to 10 % of ease, the patient underwent 8 weeks of neoadjuvant chemo- cases, mostly into the infrahepatic portion. However it may therapy with Vincristine, adriamycin, actinomycin. A repeat rarely extend into the right atrium (1.4 %) [1]. The manage- CT scan showed no response to chemotherapy and there was ment of tumors that extend into the inferior vena cava is persistent tumor extension into the retrohepatic inferior vena determined by extent of tumor thrombus, possibility of tumor cava and right atrium. (Figs. 1b and 2b) embolus, histology type, responsiveness of the tumor to che- The child was operated with facility for Cardio-Pulmonary motherapy, and tumor
Indian Journal of Surgical Oncology – Springer Journals
Published: Dec 1, 2013
Keywords: surgical oncology; oncology; surgery
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