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Nonresponsiveness to Chemotherapy: A Formidable Surgical Challenge in Wilms’ Tumor with Intracardiac Extension

Nonresponsiveness to Chemotherapy: A Formidable Surgical Challenge in Wilms’ Tumor with... Indian J Surg Oncol (December 2013) 4(4):362–365 DOI 10.1007/s13193-013-0255-6 CASE REPORT Nonresponsiveness to Chemotherapy: A Formidable Surgical Challenge in Wilms’ Tumor with Intracardiac Extension Sandesh V. Parelkar & Dinesh Mundada & Sanjay N. Oak & Beejal V. Sanghvi & Prashant B. Joshi & Satish P. Kapadnis & D. K. Kulkarni Received: 25 March 2013 /Accepted: 25 June 2013 /Published online: 11 July 2013 Indian Association of Surgical Oncology 2013 Introduction Per-cutaneous computed tomography (CT) guided tumor biopsy revealed favorable Wilms’ tumor. With stage III dis- Intracaval tumor extension is reported in 4 % to 10 % of ease, the patient underwent 8 weeks of neoadjuvant chemo- cases, mostly into the infrahepatic portion. However it may therapy with Vincristine, adriamycin, actinomycin. A repeat rarely extend into the right atrium (1.4 %) [1]. The manage- CT scan showed no response to chemotherapy and there was ment of tumors that extend into the inferior vena cava is persistent tumor extension into the retrohepatic inferior vena determined by extent of tumor thrombus, possibility of tumor cava and right atrium. (Figs. 1b and 2b) embolus, histology type, responsiveness of the tumor to che- The child was operated with facility for Cardio-Pulmonary motherapy, and tumor http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Indian Journal of Surgical Oncology Springer Journals

Nonresponsiveness to Chemotherapy: A Formidable Surgical Challenge in Wilms’ Tumor with Intracardiac Extension

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Publisher
Springer Journals
Copyright
2013 Indian Association of Surgical Oncology
ISSN
0975-7651
eISSN
0976-6952
DOI
10.1007/s13193-013-0255-6
Publisher site
See Article on Publisher Site

Abstract

Indian J Surg Oncol (December 2013) 4(4):362–365 DOI 10.1007/s13193-013-0255-6 CASE REPORT Nonresponsiveness to Chemotherapy: A Formidable Surgical Challenge in Wilms’ Tumor with Intracardiac Extension Sandesh V. Parelkar & Dinesh Mundada & Sanjay N. Oak & Beejal V. Sanghvi & Prashant B. Joshi & Satish P. Kapadnis & D. K. Kulkarni Received: 25 March 2013 /Accepted: 25 June 2013 /Published online: 11 July 2013 Indian Association of Surgical Oncology 2013 Introduction Per-cutaneous computed tomography (CT) guided tumor biopsy revealed favorable Wilms’ tumor. With stage III dis- Intracaval tumor extension is reported in 4 % to 10 % of ease, the patient underwent 8 weeks of neoadjuvant chemo- cases, mostly into the infrahepatic portion. However it may therapy with Vincristine, adriamycin, actinomycin. A repeat rarely extend into the right atrium (1.4 %) [1]. The manage- CT scan showed no response to chemotherapy and there was ment of tumors that extend into the inferior vena cava is persistent tumor extension into the retrohepatic inferior vena determined by extent of tumor thrombus, possibility of tumor cava and right atrium. (Figs. 1b and 2b) embolus, histology type, responsiveness of the tumor to che- The child was operated with facility for Cardio-Pulmonary motherapy, and tumor

Journal

Indian Journal of Surgical OncologySpringer Journals

Published: Dec 1, 2013

Keywords: surgical oncology; oncology; surgery

References