Access the full text.
Sign up today, get DeepDyve free for 14 days.
C. Lucas, A. Ledgerwood, Christopher Jeffries, P. Vernier (2010)
Late association of hyperparathyroidism in septic patients with multiple organ failure.Surgery, 148 1
A. Gurr, T. Stark, M. Pearson, G. Borkowski, S. Dazert (2009)
The ciliary beat frequency of middle ear mucosa in children with chronic secretory otitis mediaEuropean Archives of Oto-Rhino-Laryngology, 266
Bei Chen, M. Antunes, Steven Claire, J. Palmer, A. Chiu, D. Kennedy, N. Cohen (2007)
Reversal of Chronic Rhinosinusitis-Associated Sinonasal Ciliary DysfunctionAmerican Journal of Rhinology & Allergy, 21
A. Livraghi, S. Randell (2007)
Cystic Fibrosis and Other Respiratory Diseases of Impaired Mucus ClearanceToxicologic Pathology, 35
L. Nguyen, J. Manoukian, S. Sobol, T. Tewfik, B. Mazer, M. Schloss, R. Taha, Q. Hamid (2004)
Similar allergic inflammation in the middle ear and the upper airway: evidence linking otitis media with effusion to the united airways concept.The Journal of allergy and clinical immunology, 114 5
M. Maurizi, G. Paludetti, F. Ottaviani, G. Almadori, S. Falcetti (1986)
Mucociliary function and nasal resistance evaluation before and after adenoidectomy.International journal of pediatric otorhinolaryngology, 11 3
I. Sando, H. Takahashi, S. Matsune, H. Aoki (1994)
Localization of function in the eustachian tube: a hypothesis.The Annals of otology, rhinology, and laryngology, 103 4 Pt 1
B. Ulusoy, H. Arbağ, O. Sarı, Fuat Yondemli (2007)
Evaluation of the Effects of Nasal Septal Deviation and its Surgery on Nasal Mucociliary Clearance in Both Nasal CavitiesAmerican Journal of Rhinology & Allergy, 21
D. Gudis, Ke-qing Zhao, N. Cohen (2012)
Acquired cilia dysfunction in chronic rhinosinusitis, 26
M. Knowles, R. Boucher (2002)
Mucus clearance as a primary innate defense mechanism for mammalian airways.The Journal of clinical investigation, 109 5
I. Kawabata, M. Paparella (1969)
Ultrastructure of normal human middle ear mucosa. Preliminary report.The Annals of otology, rhinology, and laryngology, 78 1
C. Cingi, F. Altin, H. Çaklı, E. Entok, Kezban Gurbuz, E. Cingi (2005)
Scintigraphic evaluation of nasal mucociliary activity in unilateral chronic otitis mediaThe Journal of Laryngology & Otology, 119
I. Braverman, E. Wright, C. Wang, D. Eidelman, S. Frenkiel (1998)
Human nasal ciliary-beat frequency in normal and chronic sinusitis subjects.The Journal of otolaryngology, 27 3
M. Özkırış, S. Karaçavuş, Z. Kapusuz, L. Saydam (2013)
Comparison of two different adenoidectomy techniques with special emphasize on postoperative nasal mucociliary clearance rates: coblation technique vs. cold curettage.International journal of pediatric otorhinolaryngology, 77 3
Zheng Zhu, Ying Shan, Yang Han, L. Zhu, Z. Ma (2013)
Pathological study of otitis media with effusion after treatment with intranasal pulmonary surfactantThe Laryngoscope, 123
N. Cohen (2006)
Sinonasal Mucociliary Clearance in Health and DiseaseAnnals of Otology, Rhinology & Laryngology, 115
M. Mata, L. Milián, M. Armengot, C. Carda (2014)
Gene Mutations in Primary Ciliary Dyskinesia Related to Otitis MediaCurrent Allergy and Asthma Reports, 14
B. Button, Seiko Okada, C. Frederick, William Thelin, R. Boucher (2013)
Mechanosensitive ATP Release Maintains Proper Mucus Hydration of AirwaysScience Signaling, 6
H. Yazici, F. Soy, E. Kulduk, S. Doğan, R. Dündar, E. Sakarya, İ. Can (2014)
Comparison of nasal mucociliary clearance in adenoid hypertrophy with or without otitis media with effusion.International journal of pediatric otorhinolaryngology, 78 7
Luciana Martins, Roberto Guimarães, H. Becker, Maria Bedran, M. Medeiros, P. Camargos (2011)
Baixa prevalência de doenças do ouvido médio em pacientes com fibrose císticaJornal De Pediatria, 87
J. Fahy, B. Dickey (2010)
Airway mucus function and dysfunction.The New England journal of medicine, 363 23
R. Ranga, J. Singh, A. Gera, J. Yadav (2000)
Nasal mucociliary clearance in adenotonsillar hypertrophyThe Indian Journal of Pediatrics, 67
Zhaoxin Ma, Chunfu Dai, Shaoju Yang, Ming Li, Ling Qi (2007)
Protective effect of pulmonary surfactant on cilia of Eustachian tube in otitis media with effusion.International journal of pediatric otorhinolaryngology, 71 12
M. Maurizi, F. Ottaviani, G. Paludetti, G. Almadori, C. Zappone (1984)
Adenoid hypertrophy and nasal mucociliary clearance in children. A morphological and functional study.International journal of pediatric otorhinolaryngology, 8 1
D. Preciado, Katelyn Burgett, S. Ghimbovschi, M. Rose (2013)
NTHi induction of Cxcl2 and middle ear mucosal metaplasia in miceThe Laryngoscope, 123
M. Antunes, D. Gudis, N. Cohen (2009)
Epithelium, cilia, and mucus: their importance in chronic rhinosinusitis.Immunology and allergy clinics of North America, 29 4
Y. Orita, I. Sando, B. Hirsch, M. Miura, S. Hasebe, C. Balaban (2002)
Postnatal Development of the Eustachian Tube GlandsThe Laryngoscope, 112
A. Sahin‐Yilmaz, R. Naclerio (2011)
Anatomy and physiology of the upper airway.Proceedings of the American Thoracic Society, 8 1
Yi Li, Huizhan Liu, Jun Li, Qian Zhang, S. Gong, D. He (2014)
Morphology and Ciliary Motion of Mucosa in the Eustachian Tube of Neonatal and Adult GerbilsPLoS ONE, 9
J. Sadé (1967)
Ciliary activity and middle ear clearance.Archives of otolaryngology, 86 2
D. Arnaoutakis, William Collins (2011)
Correlation of mucociliary clearance and symptomatology before and after adenoidectomy in children.International journal of pediatric otorhinolaryngology, 75 10
M. Elsheikh, M. Mahfouz (2006)
Up‐Regulation of MUC5AC and MUC5B Mucin Genes in Nasopharyngeal Respiratory Mucosa and Selective Up‐Regulation of MUC5B in Middle Ear in Pediatric Otitis Media with EffusionThe Laryngoscope, 116
Jessica Shen, Emily Cope, Bei Chen, J. Leid, N. Cohen (2012)
Regulation of murine sinonasal cilia function by microbial secreted factorsInternational Forum of Allergy & Rhinology, 2
Y. Ohashi, Y. Nakai, S. Kihara, K. Maruoka, H. Ikeoka, Y. Uemura (1985)
The ciliary activity of the middle ear lining--functional and morphological observation.Auris, nasus, larynx, 12 Suppl 1
Gül ÖZLER, E. Akbay, Ayşe Akkoca, O. Karapınar, G. Simsek (2015)
Does menopause effect nasal mucociliary clearance time?European Archives of Oto-Rhino-Laryngology, 272
J. Kerschner, Wenzhou Hong, P. Khampang, Nikki Johnston (2014)
Differential response of gel-forming mucins to pathogenic middle ear bacteria.International journal of pediatric otorhinolaryngology, 78 8
A. Imberty, A. Varrot (2008)
Microbial recognition of human cell surface glycoconjugates.Current opinion in structural biology, 18 5
M. Wake, Lesley Smallman (1992)
Ciliary beat frequency of nasal and middle ear mucosa in children with otitis media with effusion.Clinical otolaryngology and allied sciences, 17 2
J. Kärjä, J. Nuutinen, P. Karjalainen (1983)
MUCOCILlARY FUNCTlON IN CHILDREN WITH SECRETORY OTITIS MEDIAActa Oto-laryngologica, 95
Jeffrey Shaari, J. Palmer, A. Chiu, K. Judy, A. Cohen, D. Kennedy, N. Cohen (2006)
Regional Analysis of Sinonasal Ciliary Beat FrequencyAmerican Journal of Rhinology & Allergy, 20
E. Horasanlı, A. Acar, B. Muslu, Melih Çayönü, Murat Çimencan, S. Kayabaşı (2015)
Assessment of nasal mucociliary clearance in anesthetists.Turkish journal of medical sciences, 45 1
B. Marple (2010)
Allergic Rhinitis and Inflammatory Airway Disease: Interactions within the Unified AirspaceAmerican Journal of Rhinology & Allergy, 24
SM Andreoli, RJ Schlosser, LF Wang, RM Mulligan, CM Discolo, DR White (2013)
Adenoid ciliostimulation in children with chronic otitis media. Otolaryngology–Head and NeckSurgery, 148
M. Ali, J. Wilson, M. Bennett, J. Pearson (2007)
Mucin gene expression in hypertrophic adenoidsActa Oto-Laryngologica, 127
R. DeMarco, E. Tamashiro, M. Rossato, Maria Ferreira, F. Valera, W. Anselmo-Lima (2013)
Ciliary ultrastructure in patients with chronic rhinosinusitis and primary ciliary dyskinesiaEuropean Archives of Oto-Rhino-Laryngology, 270
M. Collins, M. Church, K. Bakhshi, J. Osborne (1985)
Adenoid histamine and its possible relationship to secretory otitis mediaThe Journal of Laryngology & Otology, 99
Linbo Liu, S. Shastry, Suzanne Byan-Parker, Grace Houser, Kengyeh Chu, S. Birket, C. Fernandez, J. Gardecki, W. Grizzle, E. Wilsterman, E. Sorscher, S. Rowe, G. Tearney (2014)
An autoregulatory mechanism governing mucociliary transport is sensitive to mucus load.American journal of respiratory cell and molecular biology, 51 4
Claudia González, M. Espinosa, M. Sánchez, Karla Droguett, M. Ríos, Ximena Fonseca, M. Villalón (2013)
Epithelial Cell Culture from Human Adenoids: A Functional Study Model for Ciliated and Secretory CellsBioMed Research International, 2013
H. Stammberger (1992)
FUNCTIONAL ENDOSCOPIC SINUS SURGERYJapanese Journal of Rhinology, 31
Filiz Aydoğan, E. Aydın, G. Koca, Elçin Özgür, P. Atilla, Arzu Tüzüner, Şule Demirci, A. Tomruk, Göknur Öztürk, N. Seyhan, M. Korkmaz, S. Müftüoğlu, E. Samim (2015)
The effects of 2100‐MHz radiofrequency radiation on nasal mucosa and mucociliary clearance in ratsInternational Forum of Allergy & Rhinology, 5
S. Gizurarson (2015)
The effect of cilia and the mucociliary clearance on successful drug delivery.Biological & pharmaceutical bulletin, 38 4
Mathias Munkholm, J. Mortensen (2014)
Mucociliary clearance: pathophysiological aspectsClinical Physiology and Functional Imaging, 34
D. Passali, G. Passali, M. Lauriello, A. Romano, L. Bellussi, F. Passàli (2014)
Nasal Allergy and Otitis Media: A real correlation?Sultan Qaboos University medical journal, 14 1
Eugene Chang (2014)
New insights into the pathogenesis of cystic fibrosis sinusitisInternational Forum of Allergy & Rhinology, 4
B. Button, Liheng Cai, C. Ehre, M. Kesimer, D. Hill, J. Sheehan, R. Boucher, M. Rubinstein (2012)
A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway EpitheliaScience, 337
Janaína Oliveira-Maul, Heráclito Carvalho, D. Goto, Raphaela Maia, C. Fló, V. Barnabé, D. Franco, Simon Benabou, M. Perracini, W. Jacob-Filho, P. Saldiva, G. Lorenzi-Filho, B. Rubin, N. Nakagawa (2013)
Aging, diabetes, and hypertension are associated with decreased nasal mucociliary clearance.Chest, 143 4
N. Quaranta, C. Milella, L. Iannuzzi, M. Gelardi (2013)
A study of the role of different forms of chronic rhinitis in the development of otitis media with effusion in children affected by adenoid hypertrophy.International journal of pediatric otorhinolaryngology, 77 12
S. Andreoli, R. Schlosser, Ling-Feng Wang, R. Mulligan, C. Discolo, D. White (2013)
Adenoid Ciliostimulation in Children with Chronic Otitis MediaOtolaryngology–Head and Neck Surgery, 148
Mucociliary clearance (MCC), which exists in many systems, is the first defensive mechanism of the human body. Nasal MCC has an important role in transporting the secretions of the nasal cavity and paranasal sinuses along with the trapped inhaled pathogens to the nasopharynx. Physiologic or pathologic situations that effect nasal MCC, such as temperature, humidity, nasal obstruction, allergic rhinitis, chronic infections, etc., lead to impaired MCC and related local or circumjacent system disorders. With this perspective, when a unified airway with a multiple disease principle is considered, investigating the relationship between adenoid hypertrophy (AH), otitis media with effusion (OME) and nasal MCC is logical. In this review, histological and physiologic properties of nasal MCC and its possible role involving pathologic situations such as AH and OME is discussed together with recent literature findings.
Current Allergy and Asthma Reports – Springer Journals
Published: Oct 26, 2015
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.