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Multiple Ipsilateral Breast Cancers: Current Strategies for Surgical Management

Multiple Ipsilateral Breast Cancers: Current Strategies for Surgical Management Based on historic, retrospective data, most surgeons recommend mastectomy for women with multiple ipsilateral breast cancers (MIBC) due to a perceived prohibitively high risk of local recurrence. More recent retrospective studies, however, have documented acceptable local recurrence rates in women with MIBC who have undergone breast conservation with lumpectomy and radiation therapy. The recent data suggest that earlier detection, improved margin analysis, and increased use and efficacy of targeted therapies all contribute to the decreased risk of local recurrence when compared to rates historically documented in this MIBC population. Appropriate surgical management for MIBC is of growing importance. Pre-operative identification of MIBC has increased in the past decade due to the increased use of MRI and improved mammographic and sonographic sensitivity. Review of the current literature supports the use breast conservation with one or more partial mastectomies and sentinel node biopsy in appropriately selected patients with MIBC. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Breast Cancer Reports Springer Journals

Multiple Ipsilateral Breast Cancers: Current Strategies for Surgical Management

Current Breast Cancer Reports , Volume 4 (2) – Mar 23, 2012

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Publisher
Springer Journals
Copyright
Copyright © 2012 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Internal Medicine; Surgical Oncology; Oncology
ISSN
1943-4588
eISSN
1943-4596
DOI
10.1007/s12609-012-0075-7
Publisher site
See Article on Publisher Site

Abstract

Based on historic, retrospective data, most surgeons recommend mastectomy for women with multiple ipsilateral breast cancers (MIBC) due to a perceived prohibitively high risk of local recurrence. More recent retrospective studies, however, have documented acceptable local recurrence rates in women with MIBC who have undergone breast conservation with lumpectomy and radiation therapy. The recent data suggest that earlier detection, improved margin analysis, and increased use and efficacy of targeted therapies all contribute to the decreased risk of local recurrence when compared to rates historically documented in this MIBC population. Appropriate surgical management for MIBC is of growing importance. Pre-operative identification of MIBC has increased in the past decade due to the increased use of MRI and improved mammographic and sonographic sensitivity. Review of the current literature supports the use breast conservation with one or more partial mastectomies and sentinel node biopsy in appropriately selected patients with MIBC.

Journal

Current Breast Cancer ReportsSpringer Journals

Published: Mar 23, 2012

References