Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Multiparametric MRI: Local Staging of Prostate Cancer

Multiparametric MRI: Local Staging of Prostate Cancer Purpose of ReviewTo highlight the recent evidence about the use of mp-MRI in the local staging of prostate cancer, enhancing the potential benefits compared to the known and more invasive canonical staging methods.Recent FindingsMultiparametric magnetic resonance (mp-MRI) plays a key role not only in diagnosis, but also in local staging of prostate cancer, as it can assess with high accuracy the extracapsular extension of the tumor, invasion of seminal vesicles, the involvement of lymph nodes and the presence of possible bone metastases.SummaryProstate cancer is currently the most common male cancer in Europe and it is associated with a high mortality rate, which is why it is necessary to make an early and accurate diagnosis. Firstly, it is important to distinguish between a disease confined to the gland and a disease with a loco regional or remote extension, since neoplastic staging is the starting point for risk stratification, prognosis and therapeutic planning. According to the PI-RADS guidelines v 2.1 the main mp-MRI sequences necessary to obtain a complete and accurate resonance imaging are the T2-weighted sequences (T2WI), which represent the pivotal morphological sequences for local staging, together with the diffusion-weighted imaging (DWI) and dynamic sequences acquired after intravenous contrast medium administration (DCE). However, due to some limitations, mp-MRI does not have the same diagnostic power in the evaluation of lymph nodes, for which the gold standard remains the extended pelvic nodal dissection (ePLND), nor in the detection of distant metastases. For this last aspect, the next generation imaging foresees the use of whole-body MRI (WB-MRI), especially for the high accuracy in the early detection of local and remote bone metastases. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Radiology Reports Springer Journals

Multiparametric MRI: Local Staging of Prostate Cancer

Download PDF
11 pages

Loading next page...
 
/lp/springer-journals/multiparametric-mri-local-staging-of-prostate-cancer-xbLZ8BYj78

References (56)

Publisher
Springer Journals
Copyright
Copyright © Springer Science+Business Media, LLC, part of Springer Nature 2020
eISSN
2167-4825
DOI
10.1007/s40134-020-00374-y
Publisher site
See Article on Publisher Site

Abstract

Purpose of ReviewTo highlight the recent evidence about the use of mp-MRI in the local staging of prostate cancer, enhancing the potential benefits compared to the known and more invasive canonical staging methods.Recent FindingsMultiparametric magnetic resonance (mp-MRI) plays a key role not only in diagnosis, but also in local staging of prostate cancer, as it can assess with high accuracy the extracapsular extension of the tumor, invasion of seminal vesicles, the involvement of lymph nodes and the presence of possible bone metastases.SummaryProstate cancer is currently the most common male cancer in Europe and it is associated with a high mortality rate, which is why it is necessary to make an early and accurate diagnosis. Firstly, it is important to distinguish between a disease confined to the gland and a disease with a loco regional or remote extension, since neoplastic staging is the starting point for risk stratification, prognosis and therapeutic planning. According to the PI-RADS guidelines v 2.1 the main mp-MRI sequences necessary to obtain a complete and accurate resonance imaging are the T2-weighted sequences (T2WI), which represent the pivotal morphological sequences for local staging, together with the diffusion-weighted imaging (DWI) and dynamic sequences acquired after intravenous contrast medium administration (DCE). However, due to some limitations, mp-MRI does not have the same diagnostic power in the evaluation of lymph nodes, for which the gold standard remains the extended pelvic nodal dissection (ePLND), nor in the detection of distant metastases. For this last aspect, the next generation imaging foresees the use of whole-body MRI (WB-MRI), especially for the high accuracy in the early detection of local and remote bone metastases.

Journal

Current Radiology Reports – Springer Journals

Published: Nov 4, 2020

There are no references for this article.