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Multi-Objective Cognitive Model: a Supervised Approach for Multi-subject fMRI Analysis

Multi-Objective Cognitive Model: a Supervised Approach for Multi-subject fMRI Analysis In order to decode human brain, Multivariate Pattern (MVP) classification generates cognitive models by using functional Magnetic Resonance Imaging (fMRI) datasets. As a standard pipeline in the MVP analysis, brain patterns in multi-subject fMRI dataset must be mapped to a shared space and then a classification model is generated by employing the mapped patterns. However, the MVP models may not provide stable performance on a new fMRI dataset because the standard pipeline uses disjoint steps for generating these models. Indeed, each step in the pipeline includes an objective function with independent optimization approach, where the best solution of each step may not be optimum for the next steps. For tackling the mentioned issue, this paper introduces Multi-Objective Cognitive Model (MOCM) that utilizes an integrated objective function for MVP analysis rather than just using those disjoint steps. For solving the integrated problem, we proposed a customized multi-objective optimization approach, where all possible solutions are firstly generated, and then our method ranks and selects the robust solutions as the final results. Empirical studies confirm that the proposed method can generate superior performance in comparison with other techniques. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neuroinformatics Springer Journals

Multi-Objective Cognitive Model: a Supervised Approach for Multi-subject fMRI Analysis

Neuroinformatics , Volume 17 (2) – Aug 9, 2018

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References (51)

Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Biomedicine; Neurosciences; Bioinformatics; Computational Biology/Bioinformatics; Computer Appl. in Life Sciences; Neurology
ISSN
1539-2791
eISSN
1559-0089
DOI
10.1007/s12021-018-9394-9
Publisher site
See Article on Publisher Site

Abstract

In order to decode human brain, Multivariate Pattern (MVP) classification generates cognitive models by using functional Magnetic Resonance Imaging (fMRI) datasets. As a standard pipeline in the MVP analysis, brain patterns in multi-subject fMRI dataset must be mapped to a shared space and then a classification model is generated by employing the mapped patterns. However, the MVP models may not provide stable performance on a new fMRI dataset because the standard pipeline uses disjoint steps for generating these models. Indeed, each step in the pipeline includes an objective function with independent optimization approach, where the best solution of each step may not be optimum for the next steps. For tackling the mentioned issue, this paper introduces Multi-Objective Cognitive Model (MOCM) that utilizes an integrated objective function for MVP analysis rather than just using those disjoint steps. For solving the integrated problem, we proposed a customized multi-objective optimization approach, where all possible solutions are firstly generated, and then our method ranks and selects the robust solutions as the final results. Empirical studies confirm that the proposed method can generate superior performance in comparison with other techniques.

Journal

NeuroinformaticsSpringer Journals

Published: Aug 9, 2018

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