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Mechanical properties and cytotoxicity of PLA/PCL films

Mechanical properties and cytotoxicity of PLA/PCL films Thermodynamically immiscible poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) were blended and solution-cast by adding the 3% compatibilizer (tributyl citrate, TBC) of the PCL weight. In the PLA/PCL composition range of 99/1–95/5 wt%, mechanical properties of the PLA/PCL films with TBC were always superior to those of the films without TBC. The tensile strength of 42.9 ± 3.5 MPa and the elongation at break of 10.3 ± 2.7% were observed for the 93/7 PLA/PCL films without TBC, indicating that PCL addition is effective for strength and ductility. However, the tensile strength of 54.1 ± 3.4 MPa and the elongation at break of 8.8 ± 1.8% were found for the 95/5 PLA/PCL with TBC, indicating that the effect of co-addition of PCL and TBC on mechanical properties of the films is more pronounced. No cytotoxicity was observed for the PLA/PCL films regardless of TBC addition. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Biomedical Engineering Letters Springer Journals

Mechanical properties and cytotoxicity of PLA/PCL films

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References (15)

Publisher
Springer Journals
Copyright
Copyright © 2018 by Korean Society of Medical and Biological Engineering and Springer-Verlag GmbH Germany, part of Springer Nature
Subject
Engineering; Biomedical Engineering; Biological and Medical Physics, Biophysics; Biomedicine, general; Medical and Radiation Physics
ISSN
2093-9868
eISSN
2093-985X
DOI
10.1007/s13534-018-0065-4
Publisher site
See Article on Publisher Site

Abstract

Thermodynamically immiscible poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) were blended and solution-cast by adding the 3% compatibilizer (tributyl citrate, TBC) of the PCL weight. In the PLA/PCL composition range of 99/1–95/5 wt%, mechanical properties of the PLA/PCL films with TBC were always superior to those of the films without TBC. The tensile strength of 42.9 ± 3.5 MPa and the elongation at break of 10.3 ± 2.7% were observed for the 93/7 PLA/PCL films without TBC, indicating that PCL addition is effective for strength and ductility. However, the tensile strength of 54.1 ± 3.4 MPa and the elongation at break of 8.8 ± 1.8% were found for the 95/5 PLA/PCL with TBC, indicating that the effect of co-addition of PCL and TBC on mechanical properties of the films is more pronounced. No cytotoxicity was observed for the PLA/PCL films regardless of TBC addition.

Journal

Biomedical Engineering LettersSpringer Journals

Published: Apr 4, 2018

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