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Measurement error in proportional hazards models for survival data with long-term survivors

Measurement error in proportional hazards models for survival data with long-term survivors This work studies a proportional hazards model for survival data with “long-term survivors”, in which covariates are subject to linear measurement error. It is well known that the naive estimators from both partial and full likelihood methods are inconsistent under this measurement error model. For measurement error models, methods of unbiased estimating function and corrected likelihood have been proposed in the literature. In this paper, we apply the corrected partial and full likelihood approaches to estimate the model and obtain statistical inference from survival data with long-term survivors. The asymptotic properties of the estimators are established. Simulation results illustrate that the proposed approaches provide useful tools for the models considered. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Mathematicae Applicatae Sinica Springer Journals

Measurement error in proportional hazards models for survival data with long-term survivors

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References (21)

Publisher
Springer Journals
Copyright
Copyright © 2012 by Institute of Applied Mathematics, Academy of Mathematics and System Sciences, Chinese Academy of Sciences and Springer-Verlag Berlin Heidelberg
Subject
Mathematics; Applications of Mathematics; Math Applications in Computer Science; Theoretical, Mathematical and Computational Physics
ISSN
0168-9673
eISSN
1618-3932
DOI
10.1007/s10255-012-0145-7
Publisher site
See Article on Publisher Site

Abstract

This work studies a proportional hazards model for survival data with “long-term survivors”, in which covariates are subject to linear measurement error. It is well known that the naive estimators from both partial and full likelihood methods are inconsistent under this measurement error model. For measurement error models, methods of unbiased estimating function and corrected likelihood have been proposed in the literature. In this paper, we apply the corrected partial and full likelihood approaches to estimate the model and obtain statistical inference from survival data with long-term survivors. The asymptotic properties of the estimators are established. Simulation results illustrate that the proposed approaches provide useful tools for the models considered.

Journal

Acta Mathematicae Applicatae SinicaSpringer Journals

Published: Apr 29, 2012

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