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T. Sullivan, L. Yecies, G. Shatz, C. Parker, H. Wedner (1982)
Desensitization of patients allergic to penicillin using orally administered beta-lactam antibiotics.The Journal of allergy and clinical immunology, 69 3
MS Kramer (1979)
10.1001/jama.242.7.623JAMA, 242
C Roudier (1994)
10.1001/archderm.130.11.1383Arch Dermatol, 130
M Bigby (1986)
10.1001/jama.256.24.3358JAMA, 256
R. Loria, N. Finnerty, H. Wedner (1989)
Successful use of aztreonam in a patient who failed oral penicillin desensitization.The Journal of allergy and clinical immunology, 83 4
E. Ordoqui, J. Zubeldia, A. Aranzábal, M. Rubio, T. Herrero, P. Tornero, V. Rodríguez, A. Prieto, M. Baeza (1997)
Serum tryptase levels in adverse drug reactionsAllergy, 52
G. Ferguson, A. Nunn, W. Fox, A. Miller, D. Robinson, R. Tall (1971)
A second international co-operative investigation into thiacetazone side-effects. Rashes on two thiacetazone containing regimens.Tubercle, 52 3
Peter Koopmans, A. Ven, Tom Vree, J.W.M. Meer (1995)
Pathogenesis of hypersensitivity reactions to drugs in patients with HIV infection: allergic or toxic?AIDS, 9 3
M. Pirmohamed, B. Park (2001)
Genetic susceptibility to adverse drug reactions.Trends in pharmacological sciences, 22 6
JC Roujeau (1987)
10.1001/archderm.123.9.1171Arch Dermatol, 123
J. Schofield, F. Tatnall, J. Brown, D. Mccloskey, C. Navarrete, I. Leigh (1994)
Recurrent erythema multiforme: tissue typing in a large series of patientsBritish Journal of Dermatology, 131
G. Levene, H. Baker (1968)
DRUG REACTIONS II Lymphocyte Transformation in Vito and Drug HypersensitivityBritish Journal of Dermatology, 80
Caroline Roudier, E. Caumes, Olivier Rogeaux, F. Bricaire, Marc Gentilini (1994)
Adverse cutaneous reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome and Pneumocystis carinii pneumonia.Archives of dermatology, 130 11
M. Pirmohamed, A. Breckenridge, N. Kitteringham, B. Park (1998)
Fortnightly review: Adverse drug reactionsBMJ, 316
DW Bates (1995)
10.1001/jama.274.1.29JAMA, 274
J. Ring, K. Brockow, M. Ollert, R. Engst (1999)
Antihistamines in urticariaClinical & Experimental Allergy, 29
L. Wide, H. Bennich, S. Johansson (1967)
Diagnosis of allergy by an in-vitro test for allergen antibodies.Lancet, 2 7526
JohnS. Morris (1976)
INFECTIOUS-MONONUCLEOSIS RASH AFTER TALAMPICILLINThe Lancet, 307
K. Alanko, S. Stubb, K. Kauppinen (1989)
Cutaneous drug reactions: clinical types and causative agents. A five-year survey of in-patients (1981-1985).Acta dermato-venereologica, 69 3
B. Wintroub, R. Stern (1985)
Cutaneous drug reactions: pathogenesis and clinical classification.Journal of the American Academy of Dermatology, 13 2 Pt 1
K. Lanctôt, C. Naranjo (1994)
Computer‐Assisted Evaluation of Adverse Events Using a Bayesian ApproachThe Journal of Clinical Pharmacology, 34
T. Ives, E. Bentz, R. Gwyther (1992)
Dermatologic adverse drug reactions in a family medicine setting.Archives of family medicine, 1 2
PP Koopmans (1995)
10.1097/00002030-199509030-00001AIDS, 9
A. Oranje (2000)
Atopic Dermatitis (AD): Evaluation and TherapyPediatric Dermatology, 17
Jason Lazarou, B. Pomeranz, Paul Corey (1998)
Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies.JAMA, 279 15
Robert Greenberg, Timothy Berger (1990)
Nail and mucocutaneous hyperpigmentation with azidothymidine therapy.Journal of the American Academy of Dermatology, 22 2 Pt 2
R. Mulroy (1973)
Amoxycillin rash in infectious mononucleosis.British Medical Journal, 1
M. Girard (1987)
Conclusiveness of rechallenge in the interpretation of adverse drug reactions.British journal of clinical pharmacology, 23 1
D. Heimbach, L. Engrav, J. Marvin, T. Harnar, B. Grube (1987)
Toxic Epidermal Necrolysis: A Step Forward in TreatmentJAMA, 257
I. Viard, P. Wehrli, R. Bullani, P. Schneider, N. Holler, D. Salomon, T. Hunziker, J. Saurat, J. Tschopp, L. French (1998)
Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.Science, 282 5388
WL Weston (2000)
Steroids in erythema eultiforme (EM)Pediatr Dermatol, 17
J. Roujeau, R. Stern (1994)
Severe adverse cutaneous reactions to drugs.The New England journal of medicine, 331 19
T. Einarson (1993)
Drug-Related Hospital AdmissionsAnnals of Pharmacotherapy, 27
J. Camarasa (1985)
Patch test diagnosis of exfoliative dermatitis due to carbamazepineContact Dermatitis, 12
Andrew Carr, Ronald Penny, David Cooper (1993)
Efficacy and safety of rechallenge with low-dose trimethoprim-sulphamethoxazole in previously hypersensitive HIV-infected patients.AIDS, 7 1
M Pirmohamed, AM Breckenridge, NR Kitteringham, BK Park (1998)
Adverse drug reactionsBMJ, 316
L. Vaillant, I. Camenen, G. Lorette (1989)
Patch testing with carbamazepine: reinduction of an exfoliative dermatitis.Archives of dermatology, 125 2
DD Sogn (1984)
10.1016/0091-6749(84)90111-8J Allergy Clin Immunol, 74
F. Gordin, G. Simon, C. Wofsy, J. Mills (1984)
Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome.Annals of internal medicine, 100 4
K. Bauer (1993)
Coumarin-induced skin necrosis.Archives of dermatology, 129 6
R. Goulding, J. Robson, R.J.W. Bees (1953)
Intracorneal murine leprosy and its response to isoniazid.Lancet, 1 6757
Sudip Guharoy, S. Kar, James Mcgalliard (1993)
Suspected Nafcillin-Induced Interstitial NephritisAnnals of Pharmacotherapy, 27
NFJ Adkinson, EJ Middleton, CE Reed, EF Ellis (1998)
Drug allergyAllergy: Principles and Practice
O. Chosidow, J. Delchier, M. Chaumette, J. Wechsler, P. Wolkenstein, I. Bourgault, J. Roujeau, J. Revuz (1991)
Intestinal involvement in drug-induced toxic epidermal necrolysisThe Lancet, 337
R. Patterson, M. Roberts, L. Grammer (1990)
Insulin allergy: re-evaluation after two decades.Annals of allergy, 64 5
A. Konstantinow, W. Mühlbauer, B. Balda, J. Ring (2001)
[Toxic epidermal necrolysis (drug-induced Lyell's syndrome). 2. Treatment].Deutsche medizinische Wochenschrift, 126 7
R. Smith, G. Iwamoto, H. Richerson, J. Flaherty (1987)
Trimethoprim-sulfamethoxazole desensitization in the acquired immunodeficiency syndrome.Annals of internal medicine, 106 2
PC Comp (1993)
Coumarin-induced skin necrosis. Incidence, mechanisms, management and avoidanceDrug Safety, 8
G. Sacerdoti, A. Vozza, V. Ruocco (1993)
IDENTIFYING SKIN REACTIONS TO DRUGSInternational Journal of Dermatology, 32
J. Roujeau, T. Huynh, C. Bracq, J. Guillaume, J. Revuz, R. Touraine (1987)
Genetic susceptibility to toxic epidermal necrolysis.Archives of dermatology, 123 9
H. Booker (1975)
Idiosyncratic Reactions to the Antiepileptic DrugsEpilepsia, 16
D. Bates, D. Cullen, N. Laird, L. Petersen, S. Small, D. Servi, G. Laffel, B. Sweitzer, B. Shea, R. Hallisey (1995)
Incidence of Adverse Drug Events and Potential Adverse Drug Events: Implications for PreventionJAMA, 274
FE Karch (1975)
10.1001/jama.234.12.1236JAMA, 234
JF Timsit (1992)
10.1007/BF01706425Intensive Care Med, 18
D. Harle, Brian Baldo (1990)
Drugs as allergens: an immunoassay for detecting IgE antibodies to cephalosporins.International archives of allergy and applied immunology, 92 4
Todd Rm (1965)
Infant feeding with SMA. Further observations.The Lancet, 2
Belle Lee, S. Safrin (1992)
Interactions and toxicities of drugs used in patients with AIDS.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 14 3
PC Comp (1993)
10.2165/00002018-199308020-00003Drug Safety, 8
K. Alanko, S. Stubb, S. Reitamo (1987)
Topical provocation of fixed drug eruptionBritish Journal of Dermatology, 116
RH Demling (1985)
10.1056/NEJM198511283132205N Engl J Med, 313
V. Sharma, S. Dhar (1995)
Clinical Pattern of Cutaneous Drug Eruption among Children and Adolescents inPediatric Dermatology, 12
J. Veenstra, P. Veugelers, I. Keet, A. Ven, F. Miedema, J. Lange, R. Coutinho (1997)
Rapid disease progression in human immunodeficiency virus type 1-infected individuals with adverse reactions to trimethoprim-sulfamethoxazole prophylaxis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 24 5
L. Nolan, K. O'malley (1989)
Adverse drug reactions in the elderly.British journal of hospital medicine, 41 5
L Vaillant (1989)
10.1001/archderm.125.2.299bArch Dermatol, 125
G. Levene, H. Baker (1968)
Drug reactions. II. Ampicillin and infectious mononucleosis.The British journal of dermatology, 80 6
Jacques Descotes, G. Choquet-Kastylevsky (2001)
Gell and Coombs's classification: is it still valid?Toxicology, 158 1-2
Atkin Pa, Shenfield Gm (1995)
Medication-related adverse reactions and the elderly: a literature review.Adverse Drug Reactions and Toxicological Reviews, 14
KA Bauer (1993)
10.1001/archderm.129.6.766Arch Dermatol, 129
M. Kramer, J. Leventhal, T. Hutchinson, A. Feinstein (1979)
An algorithm for the operational assessment of adverse drug reactions. I. Background, description, and instructions for use.JAMA, 242 7
J Revuz (1987)
10.1001/archderm.123.9.1160Arch Dermatol, 123
DM Heimbach (1987)
10.1001/jama.257.16.2171JAMA, 257
B. Stark, H. Earl, Gary Gross, William Lumry, Edward Goodman, Timothy Sullivan (1987)
Acute and chronic desensitization of penicillin-allergic patients using oral penicillin.The Journal of allergy and clinical immunology, 79 3
S. Knowles, J. Uetrecht, N. Shear (2000)
Idiosyncratic drug reactions: the reactive metabolite syndromesThe Lancet, 356
M. Moore‐Robinson, R. Warin (1967)
Effect of salicylates in urticaria.British Medical Journal, 4
M. Bigby, S. Jick, H. Jick, K. Arndt (1986)
Drug-induced cutaneous reactions. A report from the Boston Collaborative Drug Surveillance Program on 15,438 consecutive inpatients, 1975 to 1982.JAMA, 256 24
Howard Heller (2000)
Adverse cutaneous drug reactions in patients with human immunodeficiency virus-1 infection.Clinics in dermatology, 18 4
Drugs are potent chemicals that often have effects in the body beyond the desired action. These effects may range from mild and expected side effects to dramatic and lifethreatening anaphylaxis. Adverse drug reactions account for between 2% and 6% of hospital admissions and may prevent administration of otherwise effective therapeutic agents. Cutaneous and mucocutaneous eruptions are the most common adverse reactions to oral or parenteral drug therapy, and the spectrum ranges from transitory exanthematous rash to the potentially fatal toxic epidermal necrolysis. Different mechansims, including both immunologic and nonimmunologic, are responsible for cutaneous adverse drug reaction. The treatment of cutaneous drug eruptions essentially rests on accurate history, a thorough physical examination, discontinuation of the offending drug, and supportive care. The management of a cutaneous drug eruption is very much individualized, based on the clinical setting. This review aims to provide a general approach to the patient with a presumed cutaneous drug reaction.
Current Allergy and Asthma Reports – Springer Journals
Published: Jan 1, 2002
Keywords: Adverse Drug Reaction; Urticaria; Allergy Clin Immunol; Toxic Epidermal Necrolysis; Drug Eruption
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