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Petrova et al. Clinical and Translational Allergy 2015, 5(Suppl 2):P15 http://www.ctajournal.com/content/5/S2/P15 POSTER PRESENTATION Open Access Long-term inhaled corticosteroid treatment and severe asthma in children - the impact on body height and weight 1 1 1* 1 2 Guergana Petrova , Vera Papochieva , Snezhina Lazova , Dimitrinka Miteva , Ljupco Zafirovski , 3 1 Lihnida Zafirovska-Matovska , Penka Perenovska From 2nd International Severe Asthma Forum (ISAF) Athens, Greece. 13-15 November 2014 Background or over 5 years)(p>0,1), the same results came for weight Chronic conditions such as asthma are usually stigma- (p>0,1) and BMI (p>0,1). Comparing with the control tized as one of the reasons for short stature. A wide- group, there is not a significant difference in weight spread belief also is that prolonged long-term treatment (p=0,07 asthma vs controls, p=0,15 asthma on ICS vs controls), height (p=0.06 asthma on ICS vs. controls). with corticosteroids will lead to elevated body weight and also could lead to short stature. Severe asthma patients (11 on high dose combined cor- Therefore we evaluated the height and weight status ticosteroids ± montelucast) also don’t show any signifi- in the children admitted in the hospital for asthma cant difference in height, BMI and weight compared to attack regarding the asthma severity, the natural history other asthma patients (p>0,5). Long-term not treated of asthma and inhaled corticosteroid (ICS) treatment asthmatics also don’t have any significant difference in period. anthropometric data compared to other asthmatics. Material and method Conclusion For a period of 6 months (Jan- Jun 2014) we evaluated Long-term ICS therapy or not proper treatment is not that 100 (54 boys, mean age 7,48±0.53 and 46 girls, mean determining for height and weight status in asthma age 7.66±0.64) children admitted for asthma attack. A patients. Interesting future study would determine detailed natural history, disease summary, pulmonary whether there is a correlation between different food beha- function test, bronchodilation test and anthropometric vior and exercise pattern that could lead the previously data were gathered, as well as data for a control group published data. of 132 patients with acute respiratory infections matched by age and sex. Authors’ details 1 2 UH “Alexandrovska”, Pediatric clinic, Sofia, Bulgaria. Children’s Hospital for Results Respiratory Diseases and TB, Respiratory departement, Skopje, Macedonia. Sana-Klinik, Pediatric department, Bergen, Germany. 49 asthmatic patients have been using ICS (18 for more than 5 years). There were not any significant correla- Published: 23 March 2015 tions between height, weight, BMI (SDS) and the ICS treatment period, the time without controller therapy, BDR response, birth weight, the asthma duration, family doi:10.1186/2045-7022-5-S2-P15 history or atopy status (p>0,05, r 0,01-0,2). No differ- Cite this article as: Petrova et al.: Long-term inhaled corticosteroid treatment and severe asthma in children - the impact on body height ences were found in height SDS when the kids were and weight. Clinical and Translational Allergy 2015 5(Suppl 2):P15. stratified according ICS treatment and its duration (less UH “Alexandrovska”, Pediatric clinic, Sofia, Bulgaria Full list of author information is available at the end of the article © 2015 Petrova et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Clinical and Translational Allergy – Springer Journals
Published: Mar 23, 2015
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