Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Engel, J. Kerr, A. Schlesinger-raab, R. Eckel, H. Sauer, D. Hölzel (2003)
Quality of Life in Rectal Cancer Patients: A Four-Year Prospective StudyAnnals of Surgery, 238
Jeonghyun Kang, H. Hur, B. Min, K. Lee, N. Kim (2011)
Robotic Coloanal Anastomosis with or without Intersphincteric Resection for Low Rectal Cancer: Starting with the Perianal Approach Followed by Robotic ProcedureAnnals of Surgical Oncology, 19
N. Saitō, Y. Moriya, K. Shirouzu, K. Maeda, H. Mochizuki, K. Koda, T. Hirai, M. Sugito, Masaaki Ito, A. Kobayashi (2006)
Intersphincteric Resection in Patients with Very Low Rectal Cancer: A Review of the Japanese ExperienceDiseases of the Colon & Rectum, 49
R. Chamlou, Y. Parc, T. Simon, M. Bennis, N. Dehni, R. Parc, E. Tiret (2007)
Long-term Results of Intersphincteric Resection for Low Rectal CancerAnnals of Surgery, 246
N. Saitō, M. Sugito, Masaaki Ito, A. Kobayashi, Y. Nishizawa, Y. Yoneyama, Y. Nishizawa, Nozomi Minagawa (2009)
Oncologic Outcome of Intersphincteric Resection for Very Low Rectal CancerWorld Journal of Surgery, 33
D Karobi SK Shaffy (2014)
Psychosocial experience of the patients with colostomy/ilesotomy: a qualitative studyIndian J Soc Psychiatry, 30
E. Silberfein, K. Kattepogu, Chung-Yuan Hu, J. Skibber, M. Rodriguez-Bigas, B. Feig, P. Das, S. Krishnan, C. Crane, S. Kopetz, C. Eng, G. Chang (2010)
Long-Term Survival and Recurrence Outcomes Following Surgery for Distal Rectal CancerAnnals of Surgical Oncology, 17
G. Barisic, V. Marković, Milos Popovic, I. Dimitrijević, P. Gavrilović, Z. Krivokapic (2011)
Function after intersphincteric resection for low rectal cancer and its influence on quality of lifeColorectal Disease, 13
E. Rullier, C. Laurent, F. Brétagnol, A. Rullier, V. Vendrely, F. Zerbib (2005)
Sphincter-Saving Resection for All Rectal Carcinomas: The End of the 2-cm Distal RuleAnnals of Surgery, 241
H. Tilney, P. Tekkis (2007)
Extending the horizons of restorative rectal surgery: intersphincteric resection for low rectal cancerColorectal Disease, 10
G. Çipe, M. Muslumanoglu, E. Yardimci, N. Memmi, E. Aysan (2012)
Intersphincteric Resection and Coloanal Anastomosis in Treatment of Distal Rectal CancerInternational Journal of Surgical Oncology, 2012
Bray F Forman D (2013)
Cancer incidence in five continents, Vol
Jun Park, G. Choi, S. Jun, S. Hasegawa, Y. Sakai (2011)
Laparoscopic Versus Open Intersphincteric Resection and Coloanal Anastomosis for Low Rectal Cancer: Intermediate-Term Oncologic OutcomesAnnals of Surgery, 254
F. Brétagnol, E. Rullier, C. Laurent, F. Zerbib, Renaud Gontier, J. Saric (2004)
Comparison of Functional Results and Quality of Life Between Intersphincteric Resection and Conventional Coloanal Anastomosis for Low Rectal CancerDiseases of the Colon & Rectum, 47
L. Smith, J. Jorge, S. Wexner (1993)
Etiology and management of fecal incontinenceDiseases of the Colon & Rectum, 36
Kazutaka Yamada, Shunji Ogata, Yasumitsu Saiki, Mitsuko Fukunaga, Y. Tsuji, M. Takano (2009)
Long-Term Results of Intersphincteric Resection for Low Rectal CancerDiseases of the Colon & Rectum, 52
S. Martin, H. Heneghan, D. Winter (2012)
Systematic review of outcomes after intersphincteric resection for low rectal cancerBritish Journal of Surgery, 99
C. Laurent, T. Paumet, F. Leblanc, Q. Denost, E. Rullier (2012)
Intersphincteric resection for low rectal cancer: laparoscopic vs open surgery approachColorectal Disease, 14
D. Damodaran, R. Seshadri (2016)
Clinicopathological attributes and outcomes of treatment in young-onset rectal cancerInternational Journal of Colorectal Disease, 31
Q. Leong, Dong-Nyung Son, J. Cho, S. Baek, J. Kwak, A. Amar, S. Kim (2011)
Robot-assisted intersphincteric resection for low rectal cancer: technique and short-term outcome for 29 consecutive patientsSurgical Endoscopy, 25
E. Vidhubala, R. Ravikannan, C. Mani, R. Muthuvel, V. Surendren, F. Paul (2011)
Validation of cancer institute quality of life questionnaire version II for cancer patients in India.Indian journal of cancer, 48 4
L. Kuo, C. Hung, Chien-Hua Wu, Web Wang, K. Tam, Hung‐Hua Liang, Yu-Jia Chang, P. Wei (2011)
Oncological and functional outcomes of intersphincteric resection for low rectal cancer.The Journal of surgical research, 170 1
K. Emmertsen, S. Laurberg (2012)
Low Anterior Resection Syndrome Score: Development and Validation of a Symptom-Based Scoring System for Bowel Dysfunction After Low Anterior Resection for Rectal CancerAnnals of Surgery, 255
R. Schiessel, G. Novi, B. Holzer, H. Rosen, K. Renner, N. Hölbling, W. Feil, M. Urban (2005)
Technique and Long-Term Results of Intersphincteric Resection for Low Rectal CancerDiseases of the Colon & Rectum, 48
Ramakrishnan A S Clinicopathological attributes and outcomes of treatment in young-onset rectal cancer. Int J Color Dis e-pub ahead of print. DOI Deepak Damodaran (1007)
s00384-015-2266-y
V. Pai, Ashwin Souza, P. Patil, R. Engineer, S. Arya, A. Saklani (2015)
Intersphincteric resection and hand-sewn coloanal anastomosis for low rectal cancer: Short-term outcomes in the Indian settingIndian Journal of Gastroenterology, 34
A. Canda, C. Terzi, I. Gorken, I. Oztop, S. Sokmen, M. Fuzun (2010)
Effects of preoperative chemoradiotherapy on anal sphincter functions and quality of life in rectal cancer patientsInternational Journal of Colorectal Disease, 25
Abstract Surgery for low rectal cancer often involves a permanent stoma. Intersphincteric resection (ISR) with colo-anal anastomosis is a valuable sphincter sparing surgical procedure that avoids the need for permanent stoma in patients with low rectal cancer. The aim of this study was to analyze the long-term functional and oncological outcomes following ISR. This was a retrospective analysis of patients with low rectal cancer who underwent ISR with colo-anal anastomosis in our institution between 2007 and 2015. All patients had a diversion stoma. Bowel function outcomes were assessed prospectively using Wexner incontinence score, low anterior resection syndrome score (LARS), and the Cancer Institute Quality of Life (QoL) questionnaire. The histological reports were reviewed to assess the oncological adequacy of the surgery. Patterns of recurrence and survival were analyzed in this group of patients. Thirty-three patients who underwent an ISR were eligible for this study. Laparoscopic resection was performed in five patients. All the patients received neoadjuvant chemoradiation except the two who received short course radiation and one who did not receive any neoadjuvant treatment. The median distance from the anal verge to the distal edge of the tumor was 3 cm (range 1.5–5 cm). Distal resection margins and circumferential resection margins were negative in all the patients. The 30-day post-operative mortality rate was 3.03%. In 20 patients with a median follow-up of 48 months, the 3-year overall survival was 95%. One patient had recurrence in the para-aortic nodes. No patient had a local recurrence. Bowel function was assessed in 18 patients who had a minimum stoma free period of 1 year. After a median of 43 months following stoma closure, the median Wexner score was 3.56 (range 0–19), median LARS score was 4.78 (range 0–33), and the mean Cancer Institute QoL score was 151.56 ± 15.741. The QoL was average to very high with an overall acceptable quality of life. In this study, ISR was associated with acceptable long-term functional and oncological outcomes. It can be considered as a safe alternative to a permanent stoma in selected patients with low rectal cancer.
Indian Journal of Surgical Oncology – Springer Journals
Published: Dec 1, 2017
Keywords: surgical oncology; oncology; surgery
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.