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Cardiol Ther (2018) 7:89–99 https://doi.org/10.1007/s40119-017-0101-y ORIGINAL RESEARCH Long-Term Clinical Outcome of Early Generation Versus New-Generation Drug-Eluting Stents in 481 Patients Undergoing Rotational Atherectomy: A Retrospective Analysis . . . . Abdelhakim Allali Erik W. Holy Dmitry S. Sulimov Ralph Toelg Gert Richardt Mohamed Abdel-Wahab Received: August 7, 2017 / Published online: November 21, 2017 The Author(s) 2017. This article is an open access publication p\0.001). The Kaplan–Meier estimated rate of ABSTRACT cardiovascular events at 2 years showed a lower incidence of death (13.5% vs. 8.2%, log-rank Introduction: New-generation drug-eluting p = 0.13; adjusted HR after Cox regression stents (NG-DES) are superior to early generation analysis 0.49; 95% CI 0.26–0.92; p = 0.03) and a DES (EG-DES) in the majority of lesion and lower MACE rate (31.1% vs. 21.1%, log-rank patient subsets, but comparative data in p = 0.04; adjusted HR 0.65; 95% CI 0.42–0.98; patients with severely calcified coronary lesions p = 0.04) in the NG-DES group. are lacking. This study aims to compare clinical Conclusions: Although RA is performed in outcomes of EG-DES and NG-DES in patients more complex patients and lesions in the undergoing rotational atherectomy (RA) in cal- NG-DES era, use of NG-DES is associated with
Cardiology and Therapy – Springer Journals
Published: Nov 21, 2017
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