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Literature alert

Literature alert Editor James R. Baker, Jr, MD University of Michigan Medical School, 6520 MSRB 1, 1150 W Medical Center, Ann Arbor, MI 48109-0682, USA. E-mail: jbakerjr@umich.edu Asero R, Mistrello G, Roncarolo D, et al.: Allergy to nonspecific lipid transfer proteins in Rosaceae: a comparative study of different in vivo diagnostic methods. Ann Allergy Asthma Immu- nol 2001, 87:68–71. Significance: This work reinforces the difficulties in evaluating patients with oral allergy syndrome. It provides an algorithm for testing these patients based on whether they also are allergic to birch pollen. It documents the difficulty in trying to develop consistent materials for skin testing to diag- nose this important syndrome. Since the authors suggest that lipid transfer proteins are the likely antigen in this syndrome, studies with recombinant proteins should provide much better means for diagnosing these individuals. Findings: The investigators evaluated techniques for identifying patients with oral allergy syndrome. Skin testing on individuals defined with this syndrome identified different spectrums of reactivity dependent on whether or not the individuals also were allergic to birch pollen. In birch pollen– allergic patients, skin-prick tests to fresh fruits were most reliable. In contrast, in individuals without birch pollen allergy, extracts of fruit peel provided http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Allergy and Asthma Reports Springer Journals

Literature alert

Current Allergy and Asthma Reports , Volume 1 (6) – May 25, 2001
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Publisher
Springer Journals
Copyright
Copyright © 2001 by Current Science Inc.
Subject
Medicine & Public Health; Allergology; Pneumology/Respiratory System; Otorhinolaryngology; Infectious Diseases
ISSN
1529-7322
eISSN
1534-6315
DOI
10.1007/s11882-001-0056-9
Publisher site
See Article on Publisher Site

Abstract

Editor James R. Baker, Jr, MD University of Michigan Medical School, 6520 MSRB 1, 1150 W Medical Center, Ann Arbor, MI 48109-0682, USA. E-mail: jbakerjr@umich.edu Asero R, Mistrello G, Roncarolo D, et al.: Allergy to nonspecific lipid transfer proteins in Rosaceae: a comparative study of different in vivo diagnostic methods. Ann Allergy Asthma Immu- nol 2001, 87:68–71. Significance: This work reinforces the difficulties in evaluating patients with oral allergy syndrome. It provides an algorithm for testing these patients based on whether they also are allergic to birch pollen. It documents the difficulty in trying to develop consistent materials for skin testing to diag- nose this important syndrome. Since the authors suggest that lipid transfer proteins are the likely antigen in this syndrome, studies with recombinant proteins should provide much better means for diagnosing these individuals. Findings: The investigators evaluated techniques for identifying patients with oral allergy syndrome. Skin testing on individuals defined with this syndrome identified different spectrums of reactivity dependent on whether or not the individuals also were allergic to birch pollen. In birch pollen– allergic patients, skin-prick tests to fresh fruits were most reliable. In contrast, in individuals without birch pollen allergy, extracts of fruit peel provided

Journal

Current Allergy and Asthma Reports – Springer Journals

Published: May 25, 2001

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