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Les médicaments dits thymorégulateurs sont efficaces à la fois sur les épisodes aigus maniaco-dépressifs et dans le traitement de maintenance prophylactique, réduisant les risques de récurrence. Un nombre limité de médicaments répondent (incomplètement) à cette définition: lithium, carbamazépine, acide valproïque, quelques médicaments anticonvulsivants, en particulier la lamotrigine par son effet anti-dépresseur prévalent et les antipsychotiques atypiques. Dans la pratique courante l’association de ces différentes molécules est la règle polutôt que l’exception.
PSN – Springer Journals
Published: Dec 5, 2008
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