Access the full text.
Sign up today, get DeepDyve free for 14 days.
(Wang, W., Song, H.S., Keller, P.W., Alvarado-Facundo, E., Vassell, R., and Weissa, C.D., Conformational stability of the hemagglutinin of H5N1 influenza A viruses influences susceptibility to broadly neutralizing stem antibodies, J. Virol., 2018, vol. 92, no. 12.)
Wang, W., Song, H.S., Keller, P.W., Alvarado-Facundo, E., Vassell, R., and Weissa, C.D., Conformational stability of the hemagglutinin of H5N1 influenza A viruses influences susceptibility to broadly neutralizing stem antibodies, J. Virol., 2018, vol. 92, no. 12.Wang, W., Song, H.S., Keller, P.W., Alvarado-Facundo, E., Vassell, R., and Weissa, C.D., Conformational stability of the hemagglutinin of H5N1 influenza A viruses influences susceptibility to broadly neutralizing stem antibodies, J. Virol., 2018, vol. 92, no. 12., Wang, W., Song, H.S., Keller, P.W., Alvarado-Facundo, E., Vassell, R., and Weissa, C.D., Conformational stability of the hemagglutinin of H5N1 influenza A viruses influences susceptibility to broadly neutralizing stem antibodies, J. Virol., 2018, vol. 92, no. 12.
(Pleshka, S., Stein, M., Schoop, R., and Hudson, J.B., Anti-viral properties and more of action of standardized echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV), Virol. J., 2009, vol. 6, artic. no. 197.)
Pleshka, S., Stein, M., Schoop, R., and Hudson, J.B., Anti-viral properties and more of action of standardized echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV), Virol. J., 2009, vol. 6, artic. no. 197.Pleshka, S., Stein, M., Schoop, R., and Hudson, J.B., Anti-viral properties and more of action of standardized echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV), Virol. J., 2009, vol. 6, artic. no. 197., Pleshka, S., Stein, M., Schoop, R., and Hudson, J.B., Anti-viral properties and more of action of standardized echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV), Virol. J., 2009, vol. 6, artic. no. 197.
(2017)
Linear polysialoside outperforms dendritic analogs for inhibition of influenza virus infection in vitro and in vivoBiomaterials, 138
(2018)
Scanning microcalorimetry at high pressure: A new method for studying conformational and phase changesUsp. Biol. Khim., 58
(2015)
Investigation of the antiviral activity of polyelectrolytes against the influenza virusVopr. Virusol., 60
(1983)
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysJ. Immunol. Methods, 65
(2012)
Thermal stability of structurally different viruses with proven or potential relevance to food safetyJ. Appl. Microbiol., 112
(2010)
Influenza virus variation in susceptibility to inactivation by pomegranate polyphenols is determined by envelope glycoproteinsAntiviral Res., 88
(1966)
Improvement of the microtiter hemagglutination methodTransfusion, 8
(2006)
Quantitation of flaviviruses by fluorescent focus assayJ. Virol. Methods, 134
Polyelectrolytes currently play an increasingly important role in antivirus therapy. Antiviral activity towards influenza virus, measles virus, herpes simplex virus type 1, and cytomegalovirus was demonstrated for the 6000 Da polyelectrolyte polyallylamine. A nontoxic polyallylamine concentration of 30 µM at which the compound retains its antiviral effect towards measles and influenza viruses but lacks any toxic effect on human cells was previously determined. It is well known, at the same time, that simultaneous virus exposure to physical environmental factors and chemical substances causes a more significant decrease in virus infectivity. Temperature is among these physical factors since thermal exposure causes virus inactivation. Analysis of virus thermal inactivation parameters is of high practical importance when it comes to the development of vaccines against influenza virus and to the study of how virus particles infectivity decreases on various surfaces. In this view, the study of kinetic and thermodynamical characteristics of influenza virus thermal inactivation in the presence of the antiviral preparation polyallylanime is of particular interest. The paper reports that thermal inactivation of influenza virus in the temperature range of 38–60°C in the presence of polyallylamine follows the first-order reaction kinetics. Thermodynamic parameters of influenza virus thermal inactivation evidence that influenza virus surface proteins are involved in the inactivation process as a result of their interaction with polyallylamine. The obtained results show that polyallylamine may be used to accelerate thermal inactivation of the influenza virus.
Moscow University Biological Sciences Bulletin – Springer Journals
Published: May 18, 2021
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.