Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Investigation of protective properties of Shigella sonnei carbohydrate biopolymers under experimental endotoxic shock models

Investigation of protective properties of Shigella sonnei carbohydrate biopolymers under... We studied tolerogenic properties of new nonpyrogenic low-endotoxic complex preparation composed of Shigella sonnei carbohydrate biopolymers under D-galactosamine and direct experimental endotoxic shock models. Pretreatment with complex preparation (exopolysaccharide + lipopolysaccharide) S. sonnei protects mice (CBA × C57B1/6)F1 against lipopolysaccharide (E. coli O:55)-mediated death. We demonstrate correlation between increasing preimmunization dose of complex preparation with rate of survival and reduction of TNF-α serum level under a direct endotoxic shock model. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Moscow University Biological Sciences Bulletin Springer Journals

Investigation of protective properties of Shigella sonnei carbohydrate biopolymers under experimental endotoxic shock models

Loading next page...
 
/lp/springer-journals/investigation-of-protective-properties-of-shigella-sonnei-carbohydrate-C4yG50pWcl

References (26)

Publisher
Springer Journals
Copyright
Copyright © 2013 by Allerton Press, Inc.
Subject
Life Sciences; Biochemistry, general; Cell Biology; Life Sciences, general; Plant Sciences; Zoology
ISSN
0096-3925
eISSN
1934-791X
DOI
10.3103/S0096392513020053
Publisher site
See Article on Publisher Site

Abstract

We studied tolerogenic properties of new nonpyrogenic low-endotoxic complex preparation composed of Shigella sonnei carbohydrate biopolymers under D-galactosamine and direct experimental endotoxic shock models. Pretreatment with complex preparation (exopolysaccharide + lipopolysaccharide) S. sonnei protects mice (CBA × C57B1/6)F1 against lipopolysaccharide (E. coli O:55)-mediated death. We demonstrate correlation between increasing preimmunization dose of complex preparation with rate of survival and reduction of TNF-α serum level under a direct endotoxic shock model.

Journal

Moscow University Biological Sciences BulletinSpringer Journals

Published: Sep 13, 2013

There are no references for this article.