Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Investigation of possible high-energy phosphate concentration changes in the visual cortex for different stimulus frequencies

Investigation of possible high-energy phosphate concentration changes in the visual cortex for... Purpose Many works have reported changes in the visual cortex regarding stimulation with different flickering frequencies using various neuroimaging techniques. Also, many phosphorus functional magnetic resonance spectroscopy ( P-fMRS) studies have reported high-energy phosphate (HEP) changes in the visual cortex during visual stimulation at 8 Hz, compared with rest periods. However, there have been no studies attempting to measure HEP changes during visual stimulation with different flickering frequencies. The aim of this work was to use the P-fMRS technique to assess possible HEP changes during visual stimulation experiments with stimuli flickering at 4 Hz or 8 Hz, and compare the results obtained with the different frequencies. Methods Nineteen subjects participated in the study. Experiments consisted of P-fMRS acquisitions in a 3T magnetic reso- nance scanner while subjects underwent a five blocks Rest/Stimulus protocol, with stimuli flickering at either 4 Hz or 8 Hz. We assessed pH; the alpha and gamma peaks of adenosine tri-phosphate (α-ATP and γ-ATP); the ratios phosphocreatine/inorganic phosphate (Pi), and of the metabolites phosphocreatine, Pi, glycerophosphocholine, phosphoethanolamine, and glycerophosphoethanolamine with respect to α-ATP and γ-ATP; and the linewidth of the phosphocreatine peak. Results pH was stable along acquisitions for both 4 Hz and 8 Hz. No http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Biomedical Engineering Springer Journals

Investigation of possible high-energy phosphate concentration changes in the visual cortex for different stimulus frequencies

Download PDF
9 pages

Loading next page...
 
/lp/springer-journals/investigation-of-possible-high-energy-phosphate-concentration-changes-cNLXPJ4src

References (41)

Publisher
Springer Journals
Copyright
Copyright © 2019 by Sociedade Brasileira de Engenharia Biomedica
Subject
Engineering; Biomedical Engineering and Bioengineering; Biomaterials; Biomedical Engineering/Biotechnology
ISSN
2446-4732
eISSN
2446-4740
DOI
10.1007/s42600-019-00023-0
Publisher site
See Article on Publisher Site

Abstract

Purpose Many works have reported changes in the visual cortex regarding stimulation with different flickering frequencies using various neuroimaging techniques. Also, many phosphorus functional magnetic resonance spectroscopy ( P-fMRS) studies have reported high-energy phosphate (HEP) changes in the visual cortex during visual stimulation at 8 Hz, compared with rest periods. However, there have been no studies attempting to measure HEP changes during visual stimulation with different flickering frequencies. The aim of this work was to use the P-fMRS technique to assess possible HEP changes during visual stimulation experiments with stimuli flickering at 4 Hz or 8 Hz, and compare the results obtained with the different frequencies. Methods Nineteen subjects participated in the study. Experiments consisted of P-fMRS acquisitions in a 3T magnetic reso- nance scanner while subjects underwent a five blocks Rest/Stimulus protocol, with stimuli flickering at either 4 Hz or 8 Hz. We assessed pH; the alpha and gamma peaks of adenosine tri-phosphate (α-ATP and γ-ATP); the ratios phosphocreatine/inorganic phosphate (Pi), and of the metabolites phosphocreatine, Pi, glycerophosphocholine, phosphoethanolamine, and glycerophosphoethanolamine with respect to α-ATP and γ-ATP; and the linewidth of the phosphocreatine peak. Results pH was stable along acquisitions for both 4 Hz and 8 Hz. No

Journal

Research on Biomedical Engineering – Springer Journals

Published: Nov 9, 2019

There are no references for this article.