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Intraoperative Intraarterial Urokinase in Early Postoperative Stroke following Carotid Endarterectomy: A Useful Adjunct

Intraoperative Intraarterial Urokinase in Early Postoperative Stroke following Carotid... Intraoperative Intraarterial Urokinase in Early Postoperative Stroke following Carotid Endarterectomy: A Useful Adjunct Gerrit B. Winkelaar, MD, Anthony J. Salvian, MD, Peter D. Fry, MD, John D.S. Reid, MD, Philip A. Teal, MD, David C. Taylor, MD, and York N. Hsiang, MD, Vancouver, Canada The purpose of this study was to determine the efficacy of intraoperative intraarterial urokinase (UK) in patients who suffered an acute stroke immediately following carotid endarterectomy (CEA). From January 1995 to March 1998, 823 carotid endarterectomies were performed. The subsequent results showed that intraarterial UK in the setting of early post-CEA neurologic events appears to be safe and may be a useful adjunct to re-exploration in improving neurologic outcomes. (Ann Vasc Surg 1999;13:566-570.) ing the outcome of these individuals are of great INTRODUCTION importance to surgeons performing CEA. Several randomized trials have conclusively dem- Because of the promising results of trials demon- onstrated that carotid endarterectomy (CEA) is a strating improved outcome with the use of throm- 7,8 beneficial procedure in the prevention of stroke bolytic therapy in acute ischemic stroke, we have both for symptomatic and asymptomatic carotid also used thrombolysis for the post-CEA stroke pa- 1,2 stenosis. However, in order to provide the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Vascular Surgery Springer Journals

Intraoperative Intraarterial Urokinase in Early Postoperative Stroke following Carotid Endarterectomy: A Useful Adjunct

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References (19)

Publisher
Springer Journals
Copyright
Copyright © 1999 by Annals of Vascular Surgery Inc.
Subject
Medicine & Public Health; Abdominal Surgery
ISSN
0890-5096
eISSN
1615-5947
DOI
10.1007/s100169900299
pmid
10541607
Publisher site
See Article on Publisher Site

Abstract

Intraoperative Intraarterial Urokinase in Early Postoperative Stroke following Carotid Endarterectomy: A Useful Adjunct Gerrit B. Winkelaar, MD, Anthony J. Salvian, MD, Peter D. Fry, MD, John D.S. Reid, MD, Philip A. Teal, MD, David C. Taylor, MD, and York N. Hsiang, MD, Vancouver, Canada The purpose of this study was to determine the efficacy of intraoperative intraarterial urokinase (UK) in patients who suffered an acute stroke immediately following carotid endarterectomy (CEA). From January 1995 to March 1998, 823 carotid endarterectomies were performed. The subsequent results showed that intraarterial UK in the setting of early post-CEA neurologic events appears to be safe and may be a useful adjunct to re-exploration in improving neurologic outcomes. (Ann Vasc Surg 1999;13:566-570.) ing the outcome of these individuals are of great INTRODUCTION importance to surgeons performing CEA. Several randomized trials have conclusively dem- Because of the promising results of trials demon- onstrated that carotid endarterectomy (CEA) is a strating improved outcome with the use of throm- 7,8 beneficial procedure in the prevention of stroke bolytic therapy in acute ischemic stroke, we have both for symptomatic and asymptomatic carotid also used thrombolysis for the post-CEA stroke pa- 1,2 stenosis. However, in order to provide the

Journal

Annals of Vascular Surgery – Springer Journals

Published: May 1, 2014

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