Access the full text.
Sign up today, get DeepDyve free for 14 days.
(TaubRDufourJFClavienPAIL-6/gp130/Stat3Signaling pathways in liver diseases2005BerlinSpringer7789)
TaubRDufourJFClavienPAIL-6/gp130/Stat3Signaling pathways in liver diseases2005BerlinSpringer7789TaubRDufourJFClavienPAIL-6/gp130/Stat3Signaling pathways in liver diseases2005BerlinSpringer7789, TaubRDufourJFClavienPAIL-6/gp130/Stat3Signaling pathways in liver diseases2005BerlinSpringer7789
(2006)
Interleukin-6 transsignaling in inflammatory bowel disease
(KishimotoTAkiraSNarazakiMTagaTInterleukin-6 family of cytokines and gp 130Blood199586124312547632928)
KishimotoTAkiraSNarazakiMTagaTInterleukin-6 family of cytokines and gp 130Blood199586124312547632928KishimotoTAkiraSNarazakiMTagaTInterleukin-6 family of cytokines and gp 130Blood199586124312547632928, KishimotoTAkiraSNarazakiMTagaTInterleukin-6 family of cytokines and gp 130Blood199586124312547632928
(GoydosJSBrumfieldAMFrezzaEMarked elevation of serum interleukin-6 in patients with cholangiocarcinoma: validation of utility as a clinical markerAnn Surg199822739840410.1097/00000658-199803000-000129527063)
GoydosJSBrumfieldAMFrezzaEMarked elevation of serum interleukin-6 in patients with cholangiocarcinoma: validation of utility as a clinical markerAnn Surg199822739840410.1097/00000658-199803000-000129527063GoydosJSBrumfieldAMFrezzaEMarked elevation of serum interleukin-6 in patients with cholangiocarcinoma: validation of utility as a clinical markerAnn Surg199822739840410.1097/00000658-199803000-000129527063, GoydosJSBrumfieldAMFrezzaEMarked elevation of serum interleukin-6 in patients with cholangiocarcinoma: validation of utility as a clinical markerAnn Surg199822739840410.1097/00000658-199803000-000129527063
K. Cheng, Hui-Ling Tang, Fu-Tsan Chou, J. Chou, Chang-Hu Hsu, Cheng‐Ju Yu, S. Kao, Tsai-Chung Li (2009)
Cytokine evaluation in liver cirrhosis and hepatocellular carcinoma.Hepato-gastroenterology, 56 93
(2012)
Comp Clin Pathol
D. Papanicolaou, R. Wilder, S. Manolagas, G. Chrousos (1998)
The Pathophysiologic Roles of Interleukin-6 in Human DiseaseAnnals of Internal Medicine, 128
(JakabLKalabayLThe acute phase reaction syndrome: the acute phase reactants (a review)Acta Microbiol Immunol Hung1998454094189873946)
JakabLKalabayLThe acute phase reaction syndrome: the acute phase reactants (a review)Acta Microbiol Immunol Hung1998454094189873946JakabLKalabayLThe acute phase reaction syndrome: the acute phase reactants (a review)Acta Microbiol Immunol Hung1998454094189873946, JakabLKalabayLThe acute phase reaction syndrome: the acute phase reactants (a review)Acta Microbiol Immunol Hung1998454094189873946
Sandrine Lacour, J. Gautier, M. Pallardy, Ruth Roberts (2005)
Cytokines as potential biomarkers of liver toxicity.Cancer biomarkers : section A of Disease markers, 1 1
(SerebriakovNBNovikAAShamanskiĭSVDiagnostic and prognostic value of interleukin-6 in malignant non-Hodgkin’s lymphomasVestn Ross Akad Med Nauk19981032369846110)
SerebriakovNBNovikAAShamanskiĭSVDiagnostic and prognostic value of interleukin-6 in malignant non-Hodgkin’s lymphomasVestn Ross Akad Med Nauk19981032369846110SerebriakovNBNovikAAShamanskiĭSVDiagnostic and prognostic value of interleukin-6 in malignant non-Hodgkin’s lymphomasVestn Ross Akad Med Nauk19981032369846110, SerebriakovNBNovikAAShamanskiĭSVDiagnostic and prognostic value of interleukin-6 in malignant non-Hodgkin’s lymphomasVestn Ross Akad Med Nauk19981032369846110
(HaedoMRGerezJFuertesMRegulation of pituitary function by cytokinesHorm Res20097226627410.1159/00024592819844112)
HaedoMRGerezJFuertesMRegulation of pituitary function by cytokinesHorm Res20097226627410.1159/00024592819844112HaedoMRGerezJFuertesMRegulation of pituitary function by cytokinesHorm Res20097226627410.1159/00024592819844112, HaedoMRGerezJFuertesMRegulation of pituitary function by cytokinesHorm Res20097226627410.1159/00024592819844112
C. Eklund (2009)
Proinflammatory cytokines in CRP baseline regulation.Advances in clinical chemistry, 48
(Standards for clinical and histological diagnosis of canine and feline liver diseases2006PhiladelphiaSaunders)
Standards for clinical and histological diagnosis of canine and feline liver diseases2006PhiladelphiaSaundersStandards for clinical and histological diagnosis of canine and feline liver diseases2006PhiladelphiaSaunders, Standards for clinical and histological diagnosis of canine and feline liver diseases2006PhiladelphiaSaunders
C. Avramescu, V. Comănescu, S. Popescu, A. Turculeanu, M. Bălășoiu, C. Popescu, M. Lungulescu (2008)
Correlations among the serum levels of some interleukins and the histopathological aspects in chronic viral hepatitis C.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 49 1
C. Berasain, J. Castillo, M. Perugorria, M. Latasa, Jesús Prieto, Matías Avila (2009)
Inflammation and Liver CancerAnnals of the New York Academy of Sciences, 1155
(AvrămescuCSComănescuVPopescuSNCorrelations among the serum levels of some interleukins and the histopathological aspects in chronic viral hepatitis CRom J Morphol Embryol200849576218273504)
AvrămescuCSComănescuVPopescuSNCorrelations among the serum levels of some interleukins and the histopathological aspects in chronic viral hepatitis CRom J Morphol Embryol200849576218273504AvrămescuCSComănescuVPopescuSNCorrelations among the serum levels of some interleukins and the histopathological aspects in chronic viral hepatitis CRom J Morphol Embryol200849576218273504, AvrămescuCSComănescuVPopescuSNCorrelations among the serum levels of some interleukins and the histopathological aspects in chronic viral hepatitis CRom J Morphol Embryol200849576218273504
N. Serebriakov, A. Novik, S. Shamanskiĭ, I. Krivolapov, S. Voloshin, V. D'iakova, I. Snetkova, I. Katkova, E. Zhiburt (1998)
[Diagnostic and prognostic value of interleukin-6 in malignant non-Hodgkin's lymphomas].Vestnik Rossiiskoi akademii meditsinskikh nauk, 10
I. Benoy, R. Salgado, C. Colpaert, R. Weytjens, P. Vermeulen, L. Dirix (2002)
Serum interleukin 6, plasma VEGF, serum VEGF, and VEGF platelet load in breast cancer patients.Clinical breast cancer, 2 4
V. Wong, Jun Yu, Alfred Cheng, G. Wong, H. Chan, E. Chu, E. Ng, F. Chan, J. Sung, H. Chan (2009)
High serum interleukin‐6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis BInternational Journal of Cancer, 124
B. Barton (1997)
IL-6: insights into novel biological activities.Clinical immunology and immunopathology, 85 1
J. Rothuizen, S. Bunch, J. Charles, J. Cullen, V. Desmet, V. Szatmári, D. Twedt, T. Ingh, T. Winkle, R. Washabau (2006)
WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases
Stephan Barrientos, Olivera Stojadinović, M. Golinko, H. Brem, M. Tomic-Canic (2008)
PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healingWound Repair and Regeneration, 16
J. Dufour, P. Clavien, C. Trautwein, R. Graf (2008)
Signaling Pathways in Liver Diseases
(BerasainCCastilloJPerugorriaMJInflammation and liver cancer: new molecular linksAnn NY Acad Sci2009115520622110.1111/j.1749-6632.2009.03704.x19250206)
BerasainCCastilloJPerugorriaMJInflammation and liver cancer: new molecular linksAnn NY Acad Sci2009115520622110.1111/j.1749-6632.2009.03704.x19250206BerasainCCastilloJPerugorriaMJInflammation and liver cancer: new molecular linksAnn NY Acad Sci2009115520622110.1111/j.1749-6632.2009.03704.x19250206, BerasainCCastilloJPerugorriaMJInflammation and liver cancer: new molecular linksAnn NY Acad Sci2009115520622110.1111/j.1749-6632.2009.03704.x19250206
K. Migita, S. Abiru, Y. Maeda, M. Daikoku, Kazuyuki Ohata, Minoru Nakamura, A. Komori, K. Yano, H. Yatsuhashi, K. Eguchi, H. Ishibashi (2006)
Serum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infection.Human immunology, 67 1-2
Lajos Jakab, László Kalabay (1998)
The acute phase reaction syndrome: the acute phase reactants (a review).Acta microbiologica et immunologica Hungarica, 45 3-4
T. Kishimoto, S. Akira, M. Narazaki, T. Taga (1995)
Interleukin-6 family of cytokines and gp130.Blood, 86 4
(SalamonMSysa-JedrzejowskaALukamowiczJConcentration of selected cytokines in serum of patients with acne rosaceaPrzegl Lek20086537137419140384)
SalamonMSysa-JedrzejowskaALukamowiczJConcentration of selected cytokines in serum of patients with acne rosaceaPrzegl Lek20086537137419140384SalamonMSysa-JedrzejowskaALukamowiczJConcentration of selected cytokines in serum of patients with acne rosaceaPrzegl Lek20086537137419140384, SalamonMSysa-JedrzejowskaALukamowiczJConcentration of selected cytokines in serum of patients with acne rosaceaPrzegl Lek20086537137419140384
R. Freeman (2006)
Signaling Pathways in Liver DiseasesAmerican Journal of Transplantation, 6
(ChengKSTangHLChouFTCytokine evaluation in liver cirrhosis and hepatocellular carcinomaHepatogastroenterology2009561105111019760951)
ChengKSTangHLChouFTCytokine evaluation in liver cirrhosis and hepatocellular carcinomaHepatogastroenterology2009561105111019760951ChengKSTangHLChouFTCytokine evaluation in liver cirrhosis and hepatocellular carcinomaHepatogastroenterology2009561105111019760951, ChengKSTangHLChouFTCytokine evaluation in liver cirrhosis and hepatocellular carcinomaHepatogastroenterology2009561105111019760951
(1998)
Diagnostic and prognostic value of interleukin-6 in malignant nonHodgkin’s lymphomas
(KamimuraDIshiharaKHiranoTIL-6 signal transduction and its physiological roles: the signal orchestration modelRev Physiol Biochem Pharmacol200314913810.1007/s10254-003-0012-212687404)
KamimuraDIshiharaKHiranoTIL-6 signal transduction and its physiological roles: the signal orchestration modelRev Physiol Biochem Pharmacol200314913810.1007/s10254-003-0012-212687404KamimuraDIshiharaKHiranoTIL-6 signal transduction and its physiological roles: the signal orchestration modelRev Physiol Biochem Pharmacol200314913810.1007/s10254-003-0012-212687404, KamimuraDIshiharaKHiranoTIL-6 signal transduction and its physiological roles: the signal orchestration modelRev Physiol Biochem Pharmacol200314913810.1007/s10254-003-0012-212687404
(2005)
IL-6/gp130/Stat3 Signaling pathways in liver diseases
(MigitaKAbiruSMaedaYSerum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infectionHum Immunol200667273210.1016/j.humimm.2006.02.02516698422)
MigitaKAbiruSMaedaYSerum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infectionHum Immunol200667273210.1016/j.humimm.2006.02.02516698422MigitaKAbiruSMaedaYSerum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infectionHum Immunol200667273210.1016/j.humimm.2006.02.02516698422, MigitaKAbiruSMaedaYSerum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infectionHum Immunol200667273210.1016/j.humimm.2006.02.02516698422
James Goydos, A. Brumfield, E. Frezza, A. Booth, M. Lotze, S. Carty (1998)
Marked elevation of serum interleukin-6 in patients with cholangiocarcinoma: validation of utility as a clinical marker.Annals of surgery, 227 3
M. Haedo, J. Gerez, Mariana Fuertes, Damiana Giacomini, M. Páez-Pereda, M. Labeur, U. Renner, G. Stalla, E. Arzt (2009)
Regulation of Pituitary Function by CytokinesHormone Research in Paediatrics, 72
D. Kamimura, K. Ishihara, T. Hirano (2003)
IL-6 signal transduction and its physiological roles: the signal orchestration model.Reviews of physiology, biochemistry and pharmacology, 149
V. Matzaraki, K. Alexandraki, K. Venetsanou, C. Piperi, P. Myrianthefs, N. Malamos, T. Giannakakis, S. Karatzas, E. Diamanti-Kandarakis, G. Baltopoulos (2007)
Evaluation of serum procalcitonin and interleukin-6 levels as markers of liver metastasis.Clinical biochemistry, 40 5-6
F. Tacke, T. Luedde, C. Trautwein (2009)
Inflammatory Pathways in Liver Homeostasis and Liver InjuryClinical Reviews in Allergy & Immunology, 36
C Berasain, J Castillo, MJ Perugorria (2009)
Inflammation and liver cancer: new molecular linksAnn NY Acad Sci, 1155
Małgorzata Salamon, A. Sysa‐Jędrzejowska, J. Lukamowicz, Magdalena Lukamowicz, E. Świątkowska, A. Wozniacka (2008)
[Concentration of selected cytokines in serum of patients with acne rosacea].Przeglad lekarski, 65 9
(BartonBEIL-6: insights into novel biological activitiesClin Immunol Immunopathol199785162010.1006/clin.1997.44209325064)
BartonBEIL-6: insights into novel biological activitiesClin Immunol Immunopathol199785162010.1006/clin.1997.44209325064BartonBEIL-6: insights into novel biological activitiesClin Immunol Immunopathol199785162010.1006/clin.1997.44209325064, BartonBEIL-6: insights into novel biological activitiesClin Immunol Immunopathol199785162010.1006/clin.1997.44209325064
(WongVWYuJChengASWongGLChanHYHigh serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis BInt J Cancer20091242766277010.1002/ijc.2428119267406)
WongVWYuJChengASWongGLChanHYHigh serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis BInt J Cancer20091242766277010.1002/ijc.2428119267406WongVWYuJChengASWongGLChanHYHigh serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis BInt J Cancer20091242766277010.1002/ijc.2428119267406, WongVWYuJChengASWongGLChanHYHigh serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis BInt J Cancer20091242766277010.1002/ijc.2428119267406
(EklundCMProinflammatory cytokines in CRP baseline regulationAdv Clin Chem20094811113610.1016/S0065-2423(09)48005-319803417)
EklundCMProinflammatory cytokines in CRP baseline regulationAdv Clin Chem20094811113610.1016/S0065-2423(09)48005-319803417EklundCMProinflammatory cytokines in CRP baseline regulationAdv Clin Chem20094811113610.1016/S0065-2423(09)48005-319803417, EklundCMProinflammatory cytokines in CRP baseline regulationAdv Clin Chem20094811113610.1016/S0065-2423(09)48005-319803417
(BarrientosSStojadinovicOGolinkoMSGrowth factors and cytokines in wound healingWound Repair Regen20081658560110.1111/j.1524-475X.2008.00410.x19128254)
BarrientosSStojadinovicOGolinkoMSGrowth factors and cytokines in wound healingWound Repair Regen20081658560110.1111/j.1524-475X.2008.00410.x19128254BarrientosSStojadinovicOGolinkoMSGrowth factors and cytokines in wound healingWound Repair Regen20081658560110.1111/j.1524-475X.2008.00410.x19128254, BarrientosSStojadinovicOGolinkoMSGrowth factors and cytokines in wound healingWound Repair Regen20081658560110.1111/j.1524-475X.2008.00410.x19128254
(LacourSGautierJCPallardyMRobertsRCytokines as potential biomarkers of liver toxicityCancer Biomark20051293917192030)
LacourSGautierJCPallardyMRobertsRCytokines as potential biomarkers of liver toxicityCancer Biomark20051293917192030LacourSGautierJCPallardyMRobertsRCytokines as potential biomarkers of liver toxicityCancer Biomark20051293917192030, LacourSGautierJCPallardyMRobertsRCytokines as potential biomarkers of liver toxicityCancer Biomark20051293917192030
M. Linker‐Israeli, R. Deans, D. Wallace, J. Prehn, T. Ozeri-Chen, J. Klinenberg (1991)
Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis.Journal of immunology, 147 1
(GoldbergRBCytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complicationsJ Clin Endocrinol Metab2009943171318210.1210/jc.2008-253419509100)
GoldbergRBCytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complicationsJ Clin Endocrinol Metab2009943171318210.1210/jc.2008-253419509100GoldbergRBCytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complicationsJ Clin Endocrinol Metab2009943171318210.1210/jc.2008-253419509100, GoldbergRBCytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complicationsJ Clin Endocrinol Metab2009943171318210.1210/jc.2008-253419509100
K. Mitsuyama, M. Sata, S. Rose-John (2006)
Interleukin-6 trans-signaling in inflammatory bowel disease.Cytokine & growth factor reviews, 17 6
S Barrientos, O Stojadinovic, MS Golinko (2008)
Growth factors and cytokines in wound healingWound Repair Regen, 16
(MitsuyamaKSataMRose-JohnSInterleukin-6 trans-signaling in inflammatory bowel diseaseCytokine Growth Factor Rev20061745146110.1016/j.cytogfr.2006.09.00317045835)
MitsuyamaKSataMRose-JohnSInterleukin-6 trans-signaling in inflammatory bowel diseaseCytokine Growth Factor Rev20061745146110.1016/j.cytogfr.2006.09.00317045835MitsuyamaKSataMRose-JohnSInterleukin-6 trans-signaling in inflammatory bowel diseaseCytokine Growth Factor Rev20061745146110.1016/j.cytogfr.2006.09.00317045835, MitsuyamaKSataMRose-JohnSInterleukin-6 trans-signaling in inflammatory bowel diseaseCytokine Growth Factor Rev20061745146110.1016/j.cytogfr.2006.09.00317045835
Chun-Hsiung Chen, D. Yu, C. Chou (2009)
Biomarkers in spondyloarthropathies.Advances in experimental medicine and biology, 649
(MatzarakiVAlexandrakiKIVenetsanouKEvaluation of serum procalcitonin and interleukin-6 levels as markers of liver metastasisClin Biochem20074033634210.1016/j.clinbiochem.2006.10.02717306245)
MatzarakiVAlexandrakiKIVenetsanouKEvaluation of serum procalcitonin and interleukin-6 levels as markers of liver metastasisClin Biochem20074033634210.1016/j.clinbiochem.2006.10.02717306245MatzarakiVAlexandrakiKIVenetsanouKEvaluation of serum procalcitonin and interleukin-6 levels as markers of liver metastasisClin Biochem20074033634210.1016/j.clinbiochem.2006.10.02717306245, MatzarakiVAlexandrakiKIVenetsanouKEvaluation of serum procalcitonin and interleukin-6 levels as markers of liver metastasisClin Biochem20074033634210.1016/j.clinbiochem.2006.10.02717306245
R. Taub (2005)
IL-6/gpl30/Stat3
(2005)
IL-6/gp130/Stat3. In: Dufour JF, Clavien PA (eds) Signaling pathways in liver diseases
(TackeFLueddeTTrautweinCInflammatory pathways in liver homeostasis and liver injuryClin Rev Allergy Immunol20093641210.1007/s12016-008-8091-018600481)
TackeFLueddeTTrautweinCInflammatory pathways in liver homeostasis and liver injuryClin Rev Allergy Immunol20093641210.1007/s12016-008-8091-018600481TackeFLueddeTTrautweinCInflammatory pathways in liver homeostasis and liver injuryClin Rev Allergy Immunol20093641210.1007/s12016-008-8091-018600481, TackeFLueddeTTrautweinCInflammatory pathways in liver homeostasis and liver injuryClin Rev Allergy Immunol20093641210.1007/s12016-008-8091-018600481
(PapanicolaouDAWilderRLManolagasSCChrousosGPThe pathophysiologic roles of interleukin-6 in human diseaseAnn Intern Med199812821272137)
PapanicolaouDAWilderRLManolagasSCChrousosGPThe pathophysiologic roles of interleukin-6 in human diseaseAnn Intern Med199812821272137PapanicolaouDAWilderRLManolagasSCChrousosGPThe pathophysiologic roles of interleukin-6 in human diseaseAnn Intern Med199812821272137, PapanicolaouDAWilderRLManolagasSCChrousosGPThe pathophysiologic roles of interleukin-6 in human diseaseAnn Intern Med199812821272137
S. Kotake, Kazuto Sato, Kang-Jung Kim, N. Takahashi, N. Udagawa, I. Nakamura, A. Yamaguchi, T. Kishimoto, T. Suda, S. Kashiwazaki (1996)
Interleukin‐6 and soluble interleukin‐6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast‐like cell formationJournal of Bone and Mineral Research, 11
(Linker-IsraeliMDeansRJWallaceDJElevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesisJ Immunol19911471171232051017)
Linker-IsraeliMDeansRJWallaceDJElevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesisJ Immunol19911471171232051017Linker-IsraeliMDeansRJWallaceDJElevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesisJ Immunol19911471171232051017, Linker-IsraeliMDeansRJWallaceDJElevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesisJ Immunol19911471171232051017
(2005)
IL - 6 / gp 130 / Stat 3
(ChenCHYuDTChouCTBiomarkers in spondyloarthropathiesAdv Exp Med Biol200964912213210.1007/978-1-4419-0298-6_919731625)
ChenCHYuDTChouCTBiomarkers in spondyloarthropathiesAdv Exp Med Biol200964912213210.1007/978-1-4419-0298-6_919731625ChenCHYuDTChouCTBiomarkers in spondyloarthropathiesAdv Exp Med Biol200964912213210.1007/978-1-4419-0298-6_919731625, ChenCHYuDTChouCTBiomarkers in spondyloarthropathiesAdv Exp Med Biol200964912213210.1007/978-1-4419-0298-6_919731625
(KotakeSSatoKKimKJTakahashiNInterleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formationJ Bone Miner Res199611889510.1002/jbmr.56501101138770701)
KotakeSSatoKKimKJTakahashiNInterleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formationJ Bone Miner Res199611889510.1002/jbmr.56501101138770701KotakeSSatoKKimKJTakahashiNInterleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formationJ Bone Miner Res199611889510.1002/jbmr.56501101138770701, KotakeSSatoKKimKJTakahashiNInterleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formationJ Bone Miner Res199611889510.1002/jbmr.56501101138770701
R. Goldberg (2009)
Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications.The Journal of clinical endocrinology and metabolism, 94 9
(BenoyISalgadoRColpaertCSerum interleukin 6, plasma VEGF, serum VEGF, and VEGF platelet load in breast cancer patientsClin Breast Canc2008231131510.3816/CBC.2002.n.008)
BenoyISalgadoRColpaertCSerum interleukin 6, plasma VEGF, serum VEGF, and VEGF platelet load in breast cancer patientsClin Breast Canc2008231131510.3816/CBC.2002.n.008BenoyISalgadoRColpaertCSerum interleukin 6, plasma VEGF, serum VEGF, and VEGF platelet load in breast cancer patientsClin Breast Canc2008231131510.3816/CBC.2002.n.008, BenoyISalgadoRColpaertCSerum interleukin 6, plasma VEGF, serum VEGF, and VEGF platelet load in breast cancer patientsClin Breast Canc2008231131510.3816/CBC.2002.n.008
Cytokines are part of pathogenesis in many diseases. Their measurement could be interesting for diagnostic purposes. One cytokine which participates in different inflammatory and neoplastic diseases is interleukin-6 (IL-6). The aim of this study was to investigate the IL-6 serum concentration in dogs with different liver diseases to show if there is any association between the cytokine serum level and the disease aetiology or the degree of the disease. IL-6 was measured in dogs with acute hepatitis, chronic hepatitis of different degrees and primary and secondary liver tumours. The data were compared with clinically healthy dogs and dogs with extra-hepatic diseases. For measurement, a commercial ELISA Kit (R&D Systems) was used. Compared with clinically healthy dogs and dogs with diabetes mellitus, all dogs with an intra- or extra-hepatic inflammatory or neoplastic disease have increased serum levels of IL-6. Dogs with acute hepatitis have significantly increased IL-6 serum concentrations compared with dogs with chronic hepatitis (P < 0.05). No significant difference between mild and moderate chronic hepatitis exists (P > 0.05). Dogs with secondary liver tumours have significantly increased IL-6 serum concentrations in comparison to dogs with primary liver tumours (P < 0.01), but both groups have comparable IL-6 serum concentration to dogs with extra-hepatic tumours. Measurement of IL-6 serum concentration may help differentiate between acute and chronic hepatitis and between primary and secondary liver tumours. Further information about the aetiology of the liver disease cannot be obtained by measuring IL-6 in the serum.
Comparative Clinical Pathology – Springer Journals
Published: Nov 19, 2010
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.