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- Publisher
- Springer Journals
- Copyright
- Copyright © 2019 by The Chinese Society of Theoretical and Applied Mechanics and Springer-Verlag GmbH Germany, part of Springer Nature
- Subject
- Engineering; Theoretical and Applied Mechanics; Classical and Continuum Physics; Engineering Fluid Dynamics; Computational Intelligence
- ISSN
- 0567-7718
- eISSN
- 1614-3116
- DOI
- 10.1007/s10409-019-00878-7
- Publisher site
- See Article on Publisher Site
Abstract
Hemodynamics plays a crucial role in the development and progression of coronary atherosclerosis, which is prone to occur in branch bifurcation. An individual aortic-coronary artery model and three changed bifurcation angle models are constructed by Mimics and Freeform based on computed tomography angiography. The influence of different coronary bifurcation angles between left main (LM), left anterior descending (LAD), and left circumflex (LCX) on the blood flow field and related hemodynamic parameters are studied. It is shown that a wider bifurcation angle between LAD and LCX can cause a wider low-wall shear stress area, leading to atherosclerosis. Similarly, a decreased angle between LM and LAD is predisposed to prevent atherosclerosis. The results help to better understand the hemodynamic causes of atherosclerosis with various bifurcation angles in coronary arteries and to provide guidance for clinical assessment and prevention.
Journal
Acta Mechanica Sinica – Springer Journals
Published: Jun 24, 2019