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J Liu, YP Liu, SM Habeebu, CD Klaassen (1998)
Susceptibility of MT-null mice to chronic CdCl2 induced nephrotoxicity indicates that renal injury is not mediated by the Cd–MT ComplexToxicological Sciences, 46
NE Alvarado, I Quesada, K Hylland, I Marigomez, M Soto (2006)
Quantitative changes in metallothionein expression in target cell-types in the gills of turbot (Scophthalmus maximus) exposed to Cd, Cu, Zn and after a depuration treatmentAquatic Toxicology, 77
TJ Hara (1992)
Fish chemoreception
RE Dudley, LM Gammal, CD Klaassen (1985)
Cadmium induced hepatic and renal injury in chronically exposed rats: Likely role of hepatic cadmium metallothionein in nephrotoxicityToxicology and Applied Pharmacology, 77
L Hastings, JE Evans (1991)
Olfactory primary neurons as a route of entry for toxic agents into the CNSNeurotoxicology, 12
Z Dang, AC Robert, G Flik, E Sjored, SE Wendelaar Bonga (1999)
Metallothionein response in gills of Oreochromis mossambicus exposed to copper in freshwaterAmerican Journal of Physiology, 277
J Gottofrey, H Tjälve (1991)
Axonal transport of cadmium in the olfactory nerve of the pikePharmacology and Toxicology, 69
SL Starcevic, BS Zielinski (1997)
Glutathione and glutathione S-transferase in the rainbow trout olfactory mucosa during retrograde degeneration and regeneration of the olfactory nerveExperimental Neurology, 146
CD Klaassen, J Liu, S Choudhuri (1999)
Metallothionein: An intercellular protein to protect against cadmium toxicityAnnual Review of Pharmacology and Toxicology, 39
I Bremner, JH Beattie (1990)
Metallothionein and the trace mineralsAnnual Reviews of Nutrition, 10
RJ Cousins (1985)
Absorption, transport and hepatic metabolism of copper and Zn: Special reference to metallothionein and ceruloplasminPhysiological Review, 65
A Shimada, Y Nagayama, T Morita, M Yashida, JS Suzuki, M Satoh, C Tohyama (2005)
Localization and role of metallothioneins in the olfactory pathway after exposure to mercury vaporExperimental Toxicology and Pathology, 57
CD Klaassen, SZ Cagens (1981)
Metallothionein as a trap for reactive oxygen intermediatesAdvances in Experimental Medicine and Biology, 136
DK Mandal, D Roy, L Ghosh (2005)
Structural organization of the olfactory epithelium of a spotted snakehead fish, Channa punctatusActa Ichthyologica et Piscatoria, 35
SL Starcevic, BS Zielinski (1995)
Immunohistochemical localization of glutathione S-transference in rainbow trout olfactory receptor neuronsNeuroscience Letter, 183
J Tallkvist, E Persson, J Henriksson, H Tjälve (2002)
Cadmium metallothionein interaction in the olfactory pathways of rat and pikesToxicological Sciences, 67
KK Banger, JR Faster, EA Lock, CJ Reed (1994)
Immunohistochemical localization of six glutathione S-transferase within the nasal cavity of the ratArchives of Toxicology, 69
SM Hsu, L Raine, H Fanger (1981)
Use of avidin–biotin peroxidase complex (ABC) in immunoperoxidase technique: A comparison between ABC and unlabelled antibody (PAP) procedureJournal of Histochemistry and Cytochemistry, 29
PL Goering, CD Klaassen (1984)
Tolerance to cadmium induced hepatotoxicity following cadmium pre-treatmentToxicology and Applied Pharmacology, 74
Induction of metallothionein (MT) in the olfactory epithelium was studied immunohistochemically in the fish Channa punctatus (Bloch) exposed to sublethal concentrations of cadmium chloride (2.5 mg/l and 5.0 mg/l). Results revealed that basal level of MT synthesis occurred in the olfactory epithelium and cadmium chloride exposure induced the synthesis of MT. Olfactory receptor cells (ORCs), supporting cells (SCs), nerve fascicles and mucous cells exhibit strong immuno-reaction whereas basal cells were found negative. Results indicated that ORCs and SCs were the sites of MT synthesis. Mucous cells accumulated Cd–MT conjugates to eliminate the metal from the olfactory system.
Proceedings of the Zoological Society – Springer Journals
Published: Jun 17, 2012
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