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Induction of Metallothionein in the Olfactory Epithelium of Channa punctatus (Bloch) in Response to Cadmium Exposure: An Immunohistochemical Study

Induction of Metallothionein in the Olfactory Epithelium of Channa punctatus (Bloch) in Response... Induction of metallothionein (MT) in the olfactory epithelium was studied immunohistochemically in the fish Channa punctatus (Bloch) exposed to sublethal concentrations of cadmium chloride (2.5 mg/l and 5.0 mg/l). Results revealed that basal level of MT synthesis occurred in the olfactory epithelium and cadmium chloride exposure induced the synthesis of MT. Olfactory receptor cells (ORCs), supporting cells (SCs), nerve fascicles and mucous cells exhibit strong immuno-reaction whereas basal cells were found negative. Results indicated that ORCs and SCs were the sites of MT synthesis. Mucous cells accumulated Cd–MT conjugates to eliminate the metal from the olfactory system. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Proceedings of the Zoological Society Springer Journals

Induction of Metallothionein in the Olfactory Epithelium of Channa punctatus (Bloch) in Response to Cadmium Exposure: An Immunohistochemical Study

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References (19)

Publisher
Springer Journals
Copyright
Copyright © 2012 by Zoological Society, Kolkata, India
Subject
Life Sciences; Conservation Biology/Ecology; Animal Genetics and Genomics; Biodiversity; Life Sciences, general; Animal Anatomy / Morphology / Histology; Zoology
ISSN
0373-5893
eISSN
0974-6919
DOI
10.1007/s12595-012-0027-2
Publisher site
See Article on Publisher Site

Abstract

Induction of metallothionein (MT) in the olfactory epithelium was studied immunohistochemically in the fish Channa punctatus (Bloch) exposed to sublethal concentrations of cadmium chloride (2.5 mg/l and 5.0 mg/l). Results revealed that basal level of MT synthesis occurred in the olfactory epithelium and cadmium chloride exposure induced the synthesis of MT. Olfactory receptor cells (ORCs), supporting cells (SCs), nerve fascicles and mucous cells exhibit strong immuno-reaction whereas basal cells were found negative. Results indicated that ORCs and SCs were the sites of MT synthesis. Mucous cells accumulated Cd–MT conjugates to eliminate the metal from the olfactory system.

Journal

Proceedings of the Zoological SocietySpringer Journals

Published: Jun 17, 2012

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