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doi: 10.1684/ecn.2017.0390 Journal Identification = ECN Article Identification = 0390 Date: May 31, 2017 Time: 10:58 am 8 Eur. Cytokine Netw. Vol. 28 n 1, March 2017, 8-18 RESEARCH ARTICLE Increased serum IL-17A and Th2 cytokine levels in patients with severe uncontrolled asthma 1,2 1 3 1, 2 Takehiro Hasegawa , Hitoshi Uga , Akio Mori , Hirokazu Kurata Sysmex Corporation, Kobe, Japan Division of System Biology of Disease, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Sagamihara, Japan Correspondence: H Kurata, Sysmex Corporation, Hematology Product Engineering, 4-4-4 Takatsukadai, Nishi-Ku, Kobe 651-2271, Japan <Kurata.Hirokazu@sysmex.co.jp> Accepted for publication February 22, 2017 To cite this article: Hasegawa T, Uga H, Mori A, Kurata H. Increased serum IL-17A and Th2 cytokine levels in patients with severe uncontrolled asthma. Eur. Cytokine Netw. 2017; 28(1): 8-18 doi:10.1684/ecn.2017.0390 ABSTRACT. Asthma is a syndrome of chronic bronchial inflammation and airway remodelling. Initially, asthma has been categorized into atopic and nonatopic types, based on antigen-specific IgE levels. Moreover, recently, asthma has been classified into different endotypes based on its pathophysiology, leading to the selection of the most optimal and effective therapies. Although T
European Cytokine Network – Springer Journals
Published: Mar 1, 2017
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