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Incidental Muscle Uptake of 177Lu-DOTATATE in Peripheral Vascular Disease

Incidental Muscle Uptake of 177Lu-DOTATATE in Peripheral Vascular Disease Somatostatin receptor (SSTR)-based imaging and therapy has emerged as well-established modality in neuroendocrine tumors. However, its role in inflammation imaging is still evolving. We present a 48-year-old male with metastatic neuroendocrine tumor who underwent lutetium-177-based somatostatin receptor-based therapy. The post-therapy scan showed a focal tracer uptake in the left calf muscle in addition to the expected tracer uptake at the primary and metastatic sites. Further, cross-sectional imaging and biochemical investigations revealed peripheral vascular disease (PVD). The incidental tracer uptake in the calf on post-therapy scan potentiates the role of somatostatin receptor scintigraphy in identifying macrophage-specific inflammatory reactions. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nuclear Medicine and Molecular Imaging Springer Journals

Incidental Muscle Uptake of 177Lu-DOTATATE in Peripheral Vascular Disease

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References (10)

Publisher
Springer Journals
Copyright
Copyright © Korean Society of Nuclear Medicine 2021
ISSN
1869-3474
eISSN
1869-3482
DOI
10.1007/s13139-021-00724-4
Publisher site
See Article on Publisher Site

Abstract

Somatostatin receptor (SSTR)-based imaging and therapy has emerged as well-established modality in neuroendocrine tumors. However, its role in inflammation imaging is still evolving. We present a 48-year-old male with metastatic neuroendocrine tumor who underwent lutetium-177-based somatostatin receptor-based therapy. The post-therapy scan showed a focal tracer uptake in the left calf muscle in addition to the expected tracer uptake at the primary and metastatic sites. Further, cross-sectional imaging and biochemical investigations revealed peripheral vascular disease (PVD). The incidental tracer uptake in the calf on post-therapy scan potentiates the role of somatostatin receptor scintigraphy in identifying macrophage-specific inflammatory reactions.

Journal

Nuclear Medicine and Molecular ImagingSpringer Journals

Published: Dec 1, 2021

Keywords: Lutetium-177; DOTATATE; Neuroendocrine tumors; Peripheral vascular diseases

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