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Improvement of hydrophilicity and blood compatibility on polyethersulfone membrane by adding polyvinylpyrrolidone

Improvement of hydrophilicity and blood compatibility on polyethersulfone membrane by adding... Abstract Polyethersulfone (PES) is widely used as biomaterials due to its thermal stability, mechanical strength, and chemical inertness. Nevertheless, their blood compatibility is still not adequate for hemodialysis. Moreover, it is very difficult to change the molecular structure by chemical modification due to the very stable chemical characteristics. In this study, polyvinylpyrrolidone (PVP) was used as an additive in the preparing of PES membrane in order to improve the hydrophilicity and blood compatibility. The result shows that the PVP-added PES membrane has higher water flux, water adsorption, and lower water contact angle (CA) than the pristine PES membrane. This indicates that the hydrophilicity of PES membrane was improved through adding PVP. Moreover, adding PVP as an additive could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time, thereby improving blood compatibility of PES membrane. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Fibers and Polymers Springer Journals

Improvement of hydrophilicity and blood compatibility on polyethersulfone membrane by adding polyvinylpyrrolidone

Wang, Haitao; Yu, Tian; Zhao, Chenyu; Du, Qiyun
Fibers and Polymers , Volume 10 (1): 5 – Feb 1, 2009
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References (17)

Publisher
Springer Journals
Copyright
2009 The Korean Fiber Society and Springer-Verlag Berlin Heidelberg GmbH
ISSN
1229-9197
eISSN
1875-0052
DOI
10.1007/s12221-009-0001-4
Publisher site
See Article on Publisher Site

Abstract

Abstract Polyethersulfone (PES) is widely used as biomaterials due to its thermal stability, mechanical strength, and chemical inertness. Nevertheless, their blood compatibility is still not adequate for hemodialysis. Moreover, it is very difficult to change the molecular structure by chemical modification due to the very stable chemical characteristics. In this study, polyvinylpyrrolidone (PVP) was used as an additive in the preparing of PES membrane in order to improve the hydrophilicity and blood compatibility. The result shows that the PVP-added PES membrane has higher water flux, water adsorption, and lower water contact angle (CA) than the pristine PES membrane. This indicates that the hydrophilicity of PES membrane was improved through adding PVP. Moreover, adding PVP as an additive could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time, thereby improving blood compatibility of PES membrane.

Journal

Fibers and Polymers – Springer Journals

Published: Feb 1, 2009

Keywords: Polymer Sciences

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