Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/springer-journals/immunotherapy-for-rhinitis-k31DAQgP7h
References (42)
-
S. Durham, S. Ying, V. Varney, M. Jacobson, R. Sudderick, I. Mackay, A. Kay, Q. Hamid (1996)
Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma.The Journal of allergy and clinical immunology, 97 6
-
O. Linna, J. Kokkonen, M. Lukin (1992)
A 10‐year prognosis for childhood allergic rhinitisActa Pædiatrica, 81
-
U. Bødtger, L. Poulsen, H. Jacobi, H. Malling (2002)
The safety and efficacy of subcutaneous birch pollen immunotherapy – a one‐year, randomised, double‐blind, placebo‐controlled studyAllergy, 57
-
S. Voltolini, P. Modena, P. Minale, D. Bignardi, C. Troise, P. Puccinelli, S. Parmiani (2001)
Sublingual immunotherapy in tree pollen allergy. Double-blind, placebo-controlled study with a biologically standardised extract of three pollens (alder, birch and hazel) administered by a rush schedule.Allergologia et immunopathologia, 29 4
-
H-J Malling, J Abreu-Nogueira, E Alvarez-Cuesta (1998)
Local immunotherapy: position paper from EAACI & ESPACIAllergy, 53
-
Duncan Wilson, Anosh Irani, S. Walker, M. Jacobson, I. Mackay, Lawrence Schwartz, S Durham (2001)
Grass pollen immunotherapy inhibits seasonal increases in basophils and eosinophils in the nasal epitheliumClinical & Experimental Allergy, 31
-
S. Durham, S. Walker, E. Varga, M. Jacobson, F. O’Brien, W. Noble, S. Till, Q. Hamid, K. Nouri-Aria (1999)
Long-term clinical efficacy of grass-pollen immunotherapy.The New England journal of medicine, 341 7
-
R. Settipane, G. Hagy, G. Settipane (1994)
Long-term risk factors for developing asthma and allergic rhinitis: a 23-year follow-up study of college students.Allergy proceedings : the official journal of regional and state allergy societies, 15 1
-
GB Pajno, G Barberio, Fr Luca (2001)
n asthmatic children monosensitized to house dust mite by specific immunotherapy: a six-year follow-up studyClin Exp Allergy, 31
-
Duncan Wilson, K. Nouri-Aria, S. Walker, G. Pajno, F. O’Brien, M. Jacobson, I. Mackay, S Durham (2001)
Grass pollen immunotherapy: symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season.The Journal of allergy and clinical immunology, 107 6
-
H.-J. Mailing (1998)
Immunotherapy as an effective tool in allergy treatmentAllergy, 53
-
M. Lima, Duncan Wilson, L. Pitkin, A. Roberts, K. Nouri-Aria, M. Jacobson, S. Walker, Stephen Durham (2002)
Grass pollen sublingual immunotherapy for seasonal rhinoconjunctivitis: a randomized controlled trialClinical & Experimental Allergy, 32
-
J. Bousquet, R. Lockey, H. Malling (1998)
Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper.The Journal of allergy and clinical immunology, 102 4 Pt 1
-
S. Braman, A. Barrows, B. DeCotiis, G. Settipane, W. Corrao (1987)
Airway hyperresponsiveness in allergic rhinitis. A risk factor for asthma.Chest, 91 5
-
J Bousquet, RF Lockey, H-J Malling (1998)
WHO Position Paper. Allergen immunotherapy: therapeutic vaccines for allergic diseasesAllergy, 53
-
F. Purello-D’Ambrosio, S. Gangemi, R. Merendino, S. Isola, P. Puccinelli, S. Parmiani, L. Ricciardi (2001)
Prevention of new sensitizations in monosensitized subjects submitted to specific immunotherapy or not. A retrospective studyClinical & Experimental Allergy, 31
-
S. Rak, Christina Heinrich, L. Jacobsen, A. Scheynius, P. Venge (2001)
A double-blinded, comparative study of the effects of short preseason specific immunotherapy and topical steroids in patients with allergic rhinoconjunctivitis and asthma.The Journal of allergy and clinical immunology, 108 6
-
Francisque Leynadier, L. Banoun, B. Dollois, P. Terrier, M. Epstein, M. Guinnepain, D. Firon, C. Traube, R. Fadel, C. André (2001)
Immunotherapy with a calcium phosphate‐adsorbed five‐grass‐pollen extract in seasonal rhinoconjunctivitis: a double‐blind, placebo‐controlled studyClinical & Experimental Allergy, 31
-
G. Pajno, L. Morabito, G. Barberio, S. Parmiani (2000)
Clinical and immunologic effects of long‐term sublingual immunotherapy in asthmatic children sensitized to mites:a double‐blind, placebo‐controlled studyAllergy, 55
-
Durham, Varney, Gaga, Jacobson, Varga, Frew, Kay (1999)
Grass pollen immunotherapy decreases the number of mast cells in the skinClinical & Experimental Allergy, 29
-
N. Bahceciler, U. Işık, I. Barlan, M. Başaran (2001)
Efficacy of sublingual immunotherapy in children with asthma and rhinitis: A double‐blind, placebo‐controlled studyPediatric Pulmonology, 32
-
E. Madonini, G. Briatico-Vangosa, A. Pappacoda, G. Maccagni, A. Cardani, F. Saporiti (1987)
Seasonal increase of bronchial reactivity in allergic rhinitis.The Journal of allergy and clinical immunology, 79 2
-
C. Möller, S. Dreborg, H. Ferdousi, S. Halken, A. Høst, L. Jacobsen, A. Koivikko, D. Koller, B. Niggemann, L. Norberg, R. Urbanek, E. Valovirta, U. Wahn (2002)
Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study).The Journal of allergy and clinical immunology, 109 2
-
J. Bousquet, P. Cauwenberge, N. Khaltaev (2001)
Allergic rhinitis and its impact on asthma.The Journal of allergy and clinical immunology, 108 5 Suppl
-
M. Torres, C. Mayorga, L. Leyva, A. Guzmán, J. Cornejo‐García, C. Juarez, M. Blanca (2002)
Controlled administration of penicillin to patients with a positive history but negative skin and specific serum IgE testsClinical & Experimental Allergy, 32
-
Robert Ross, Harold Nelson, Ira Finegold (2000)
Effectiveness of specific immunotherapy in the treatment of allergic rhinitis: an analysis of randomized, prospective, single- or double-blind, placebo-controlled studies.Clinical therapeutics, 22 3
-
H. Malling (2002)
Is sublingual immunotherapy clinically effective?Current Opinion in Allergy and Clinical Immunology, 2
-
M. Khinchi, L. Poulsen, F. Carat, C. André, A. Hansen, H. Malling (2004)
Clinical efficacy of sublingual and subcutaneous birch pollen allergen‐specific immunotherapy: a randomized, placebo‐controlled, double‐blind, double‐dummy studyAllergy, 59
-
P. Eng, M. Reinhold, H. Gnehm (2002)
Long‐term efficacy of preseasonal grass pollen immunotherapy in childrenAllergy, 57
-
S. Guez, C. Vatrinet, R. Fadel, C. André (2000)
House‐dust‐mite sublingual‐swallow immunotherapy (SLIT) in perennial rhinitis: a double‐blind, placebo‐controlled studyAllergy, 55
-
R. Ariano, I. Spadolini, R. Panzani (2001)
Efficacy of sublingual specific immunotherapy in Cupressaceae allergy using an extract of Cupressus arizonica. A double blind study.Allergologia et immunopathologia, 29 6
-
F. Erel, M. Karaayvaz, A. Çalışkaner, M. Gerek, M. Demiriz, A. Kubar, N. Ozangüç (2000)
Effects of allergen immunotherapy on the nasal mucosa in patients with allergic rhinitis.Journal of investigational allergology & clinical immunology, 10 1
-
V. Varney, M. Gaga, A. Frew, V. Aber, A. Kay, S. Durham (1991)
Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs.British Medical Journal, 302
-
G. Pajno, G. Barberio, F. Luca, L. Morabito, S. Parmiani (2001)
Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six‐year follow‐up study.Clinical & Experimental Allergy, 31
-
R. Sly (1999)
Changing prevalence of allergic rhinitis and asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 82 3
-
O Linna, J Kokkonen, M Lukin (1992)
A 10-year prognosis for childhood allergic rhinitisActa Paedriatr, 81
-
C. Caffarelli, L. Sensi, Francesco Marcucci, G. Cavagni (2000)
Preseasonal local allergoid immunotherapy to grass pollen in children: a double‐blind, placebo‐controlled, randomized trialAllergy, 55
-
R Ariano, I Spadolini, RC Panzani (2001)
Efficacy of sublingual specific immunotherapy in Cupressaceae allergy using an extract of Cupressus arizonica: a double blind studyAllergol Immunopathol, 29
-
D. Mungan, Z. Mısırlıgil, L. Gurbuz (1999)
Comparison of the efficacy of subcutaneous and sublingual immunotherapy in mite-sensitive patients with rhinitis and asthma--a placebo controlled study.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 82 5
-
P. Wachholz, K. Nouri-Aria, Duncan Wilson, S. Walker, A. Verhoef, S. Till, S. Durham (2002)
Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1 : Th2 cytokine ratiosImmunology, 105
-
T. Quirino, E. Iemoli, E. Siciliani, S. Parmiani, F. Milazzo (1996)
Sublingual versus injective immunotherapy in grass pollen allergic patients: a double blind (double dummy) studyClinical & Experimental Allergy, 26
-
S. Walker, G. Pajno, M. Lima, Duncan Wilson, S. Durham (2001)
Grass pollen immunotherapy for seasonal rhinitis and asthma: a randomized, controlled trial.The Journal of allergy and clinical immunology, 107 1
- Publisher
- Springer Journals
- Copyright
- Copyright © 2003 by Current Science Inc.
- Subject
- Medicine & Public Health; Allergology; Pneumology/Respiratory System; Otorhinolaryngology; Infectious Diseases
- ISSN
- 1529-7322
- eISSN
- 1534-6315
- DOI
- 10.1007/s11882-003-0040-7
- Publisher site
- See Article on Publisher Site
Abstract
Allergen-specific immunotherapy in the treatment of allergic rhinitis has a well-documented clinical efficacy that indicates a statistically significant and clinically relevant reduction in symptom scores and the need for pharmacotherapy. The clinical efficacy of recently published studies is equivalent to or superior to the effect of standard antiallergic drugs. Additional advantages are related to a downregulation of the allergic phenotype with the additional induction of a Th1 cytokine profile. The immunoregulatory capacity and the global downregulation of the allergic inflammation in mucous membranes might be important factors in the capacity to ensure long-term clinical efficacy (after termination of treatment) and the preventive capacity of immunotherapy in reducing the progression of rhinitis to asthma as well as deflowering the development of new sensitizations. Subcutaneous immunotherapy is optimal in severe allergic rhinitis with signs of bronchial hyperreactivity; however, sublingual immunotherapy might be an option for patients with milder disease.
Journal
Current Allergy and Asthma Reports – Springer Journals
Published: May 27, 2003